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Advanced Immunology and Immunopathology Quiz

Advanced Immunology And Immunopathology Quiz

Explore the complex world of immune system responses and disorders in our Immunology\/immunopathology quiz. Assess your understanding of key immunological concepts and their pathological implications, crucial for students and...

Questions: 28 | Attempts: 10 | Last updated: Aug 4, 2025

Sample Question
What is responsible for the immediate reaction to a bee sting and what is responsible for the delayed response?

*PREFORMED ANTIBODY(IGE) is the cause of Rapid reaction after exposure.*IgE cross linking on mast cells after re-exposure to presensitized antigen >Degranulation of mast cells>Histamine release(PRE-formed, just like ArylsuflatASE(Neutralizes leukotrienes) and HistaminASE(neutralizes histamine) from eosinophils along with serotonin).*But Delayed response is due to Leukotrienes(Arachidonic acid metabolite) released from mast cells(DE NOVO synthesized not preformed- other late phase recatants are also de novo synthesized like PAF and PG) and BOY THEY WILL ASK about delayed response(6-24 hours after repeat exposure).**Note Trypatase is a marker of Mast cell degranulation.

*Leukotrienes are responsible for the immediate reaction and histamine is responsible for the delayed response.

*IgG antibodies are responsible for the immediate reaction and cytokines are responsible for the delayed response.

*Histamine release is responsible for the immediate reaction and prostaglandins are responsible for the delayed response.