Review Of Radiopharmaceutical Use In Medicine
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The following learning assessment is for the maiCE article Review of Radiopharmaceutical Use in Medicine. First, view the CE article by clicking here. Then, complete the assessment by entering your name and email and selecting "Start" below. This CE activity is worth 1. 5 Category A CE credits (RCEEM AHRA), accepted by the ARRT and the NMTCB. A score of 75% or greater must be scored to obtain credit. Your Certificate of CE Completion will be emailed to the address you use to register this test. Your name will appear on your Certificate of CE Completion as you enter it below. Please include the full name you would like on your certificat
- 1.According to the Nuclear Regulatory Commission, approximately what proportion of patients in U.S. hospitals will require radioisotopes in their course of diagnostics and treatment?
- A.
1/2
- B.
1/3
- C.
1/4
- D.
1/5
- 2.Which of the following is not used to produce radioisotopes?
- A.
Cyclotrons
- B.
Radioisotope generators
- C.
Gamma cameras
- D.
Nuclear reactors
- 3.How is the commonly used isotope Tc-99m produced?
- A.
Cyclotron
- B.
Gamma camera
- C.
Radioisotope generator
- D.
Linear accelerator
- 4.How is the positron emitter fluorine-18 produced?
- A.
Cyclotron
- B.
Gamma camera
- C.
Radioisotope generator
- D.
Linear accelerator
- 5.How is molybdenum-99 produced?
- A.
Cyclotron
- B.
Gamma camera
- C.
Radioisotope generator
- D.
Nuclear reactor
- 6.Why is molybdenum-99m important in nuclear medicine?
- A.
It is the most widely used isotope in nuclear medicine
- B.
It is the daughter-isotope of the most widely used isotope in nuclear medicine
- C.
It is the parent-isotope of the most widely used isotope in nuclear medicine
- 7.How is lack of blood perfusion visualized in nuclear medicine imaging?
- A.
“hot” spots/increased activity
- B.
“cold” spots/lack of activity
- C.
Presentation depends on the isotope used
- D.
Presentation depends on the organ being imaged
- 8.How can images taken hours after a patient has been injected under stress conditions depict blood perfusion to the heart at stress?
- A.
Images can only depict blood perfusion to the heart under resting conditions
- B.
Computer programs calculate the estimated blood perfusion under stress conditions
- C.
The radiopharmaceutical localized in the heart indicative of blood flow at the time of injection
- 9.What isotopes is not commonly used for imaging blood perfusion to the heart?
- A.
Tl-201
- B.
Tc-99m
- C.
I-131
- D.
Rb-82
- 10.Why does MAA localize in the capillaries of the lung?
- A.
It consists of particles that are too large to travel further than the lung capillaries
- B.
It is inhaled
- C.
It doesn’t localize in the capillaries of the lung
- D.
The pharmaceutical has an affinity for lung tissue
- 11.Why are radioisotopes Tc99m-labeled ECD and hexamethylpropylene HMPAO preferred for evaluation of brain death?
- A.
They have a short half-life
- B.
They are brain specific agents which allows for delayed imaging
- C.
They have few side effects which allows for delayed imaging
- D.
They have a long half-life which allows for delayed imaging
- 12.What characteristic of F-18 FDG makes it useful in tumor imaging?
- A.
The glucose component
- B.
The fluorine component
- C.
The phosphate component
- D.
The short half-life
- 13.Why does the above characteristic make F-18 FDG useful in tumor imaging?
- A.
Tumors are hypometabolic and require less fluorine than most normal tissues
- B.
Tumors are hypometabolic and require less sugar than most normal tissues
- C.
Tumors are hypermetabolic and require more fluorine than most normal tissues
- D.
Tumors are hypermetabolic and require more sugar than most normal tissues
- 14.How are radioisotopes employed for infection detection?
- A.
By tagging red blood cells with radioactivity
- B.
By tagging somatostatin receptors with radioactivity
- C.
By tagging white blood cells with radioactivity
- D.
By inhaling radioactive gas
- 15.Why is F-18 flurodeoxyglucose useful in imaging neuronal activity in the brain?
- A.
Because the brain uses fluorine for energy
- B.
Because the brain uses glucose for energy
- C.
Because diseased brain tissue requires an excess of glucose
- D.
Because diseased brain tissue requires an excess of fluorine
- 16.Gastrointestinal bleeding can be detected using nuclear medicine imaging regardless of whether or not the patient is actively bleeding at the time of radiotracer injection.
- A.
True
- B.
False
- 17.When is quantification of lung function useful?
- A.
To evaluate for pulmonary embolism
- B.
To evaluate for COPD
- C.
To assess lung function pre or post surgery
- D.
All of the above
- 18.What is often administered to patients during imaging of bladder-emptying in renal scintigraphy?
- A.
A sedative
- B.
A diuretic
- C.
IV saline
- D.
An anesthetic
- 19.A region of interest is drawn around what organ to assess biliary function?
- A.
Liver
- B.
Stomach
- C.
Intestine
- D.
Gallbladder
- 20.Why is sulfur colloid preferred in gastric emptying studies?
- A.
It’s easy to digest
- B.
It’s tasteless
- C.
It is not absorbed by surrounding tissues
- D.
It’s easily absorbed by surrounding tissues
- 21.What is the route of administration for a lymphoscintigraphy study?
- A.
Subcutaneously
- B.
Intravenously
- C.
Orally
- D.
None of the above
- 22.How do therapeutic radioisotopes generally compare to diagnostic radioisotopes?
- A.
They have a longer half-life
- B.
They have a higher energy
- C.
They have a shorter half-life
- D.
A & b
- E.
B & c
- 23.What kind of radioactivity is emitted by I-131?
- A.
Gamma
- B.
Beta
- C.
Positron
- D.
A & b
- E.
B & c
- 24.What is the most commonly used palliative treatment for bone metastasis in the United States?
- A.
P-32
- B.
Sr-89
- C.
Sm-153
- D.
I-131
- 25.What do the pharmaceuticals I-131 tositumomab and Y-90 ibritumomab have in common?
- A.
They can both be imaged for evaluation of biodistribution
- B.
They both target the CD20 antigen on B-lymphocytes
- C.
They both are used to treat Non-Hodgkin’s Lymphoma
- D.
A & b
- E.
B & c
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