Quiz For Lecture 3 - Components Of The Adaptive Immune System

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  • 1/18 Questions

    B-lymphocytes mature and differentiate in the Thymus.

    • True
    • False
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About This Quiz

Quiz to consolidate learning from Lecture 2 - Components of the Innate Immune Sytem. As ever dont worry if you get the wrong answer, simply revisit the Lecture and see if you can improve youre knowledge. Take the quiz as many times as you like. Good luck!

Immune System Quizzes & Trivia

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  • 2. 

    Cell type that is a terminally differentiated B-cell.

    • Mast Cell

    • Plasma Cell

    • Macrophage

    • Natural Killer Cell

    Correct Answer
    A. Plasma Cell
    Explanation
    A Mast Cell is a terminally differentiated Basophil.
    A macrophage is a terminally differentiated Monocyte.
    The NKC is the only cell type of the lymphoid lineage to belong to the innate immune system.

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  • 3. 

    The most prevalent immunoglobulin in serum, is also a good opsonizer and can cross the placenta.

    • IgA

    • IgE

    • IgG

    • IgM

    Correct Answer
    A. IgG
    Explanation
    IgG is also a good opsonizer.

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  • 4. 

    The cytokine IL-4, as produced by T-helper T cells acts as a growth factor for B lymphocytes – encourages differentiation into plasma cells.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    IL-4, produced by T-helper T cells, functions as a growth factor for B lymphocytes and promotes their differentiation into plasma cells. This means that IL-4 stimulates the growth and development of B cells, leading to their transformation into plasma cells, which are responsible for producing antibodies. Therefore, the statement is true.

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  • 5. 

    Immunoglobulin whose levels rise in response to parasitic infections and is described as being a mediator of Type 1 hypersensitivity reactions.

    • IgA

    • IgE

    • IgG

    • IgM

    Correct Answer
    A. IgE
    Explanation
    IgE also interacts with basophils and mast cells, causing their degranulation and release of inflammatory mediators leading to immediate hypersensitivity (allergic) reactions.

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  • 6. 

    Immunoglobulin class that is resistant to enzymatic breakdown and is found in saliva and breast milk.

    • IgA

    • IgE

    • IgG

    • IgM

    Correct Answer
    A. IgA
    Explanation
    IgA is also found on mucosal surfaces and is known to activate the Alternative Pathway of the complement system

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  • 7. 

    B-lymphocytes differentiate into mast cells.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    B-lymphocytes can differentiate into plasma or memory B-cells.

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  • 8. 

    The first immunoglobulin to be produced during an immune response that forms large pentamere structures.

    • IgA

    • IgE

    • IgG

    • IgM

    Correct Answer
    A. IgM
    Explanation
    IgM is also the main immunoglobulin involved in the activation of the complement system

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  • 9. 

    Cell type which act as antibody factories to give a faster, bigger antibody response to subsequent exposure to the same pathogen.

    • T-lymphocytes

    • Plasma cells

    • Neutrophils

    • Basophils

    Correct Answer
    A. Plasma cells
    Explanation
    T-lymphocytes don’t produce antibodies at all.
    Neutrophils are phagocytes and form part of the innate immune system.
    Basophils are implicated in the inflammatory response and form part of the innate immune system.

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  • 10. 

    The cytokine IL-2, as produced by Helper (CD4+) T cells stimulates differentiation of Cytotoxic (CD8+) T-cells, Regulatory T cells, and Natural Killer cells.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    IL-2, produced by Helper T cells, is a cytokine that plays a crucial role in the immune response. It stimulates the differentiation of various immune cells, including Cytotoxic T cells, Regulatory T cells, and Natural Killer cells. This stimulation is necessary for the immune system to effectively eliminate pathogens and maintain immune homeostasis. Therefore, the statement that IL-2 stimulates the differentiation of these cells is true.

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  • 11. 

    The Adaptive Immune System includes the cells of the myeloid lineage; being granulocytes and agranulocytes.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    The Adaptive Immune System includes the cells of the lymphoid lineage, being the B & T-lymphocytes, but NOT the Natural Killer Cell (NKC).

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  • 12. 

    Lymphocytes are the effector cells of the Innate immune system.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Lymphocytes are one of the effector cells of the Adaptive immune system.

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  • 13. 

    Protein family to which antibody and B –Cell Receptors belong. Are the antigen binding molecules of B-cells.

    • The complement system

    • Major Histocompatibility Complex (MHC)

    • Immunoglobulin

    Correct Answer
    A. Immunoglobulin
    Explanation
    The complement system is a system of blood proteins that form an enzymatic cascade, opsonizing pathogens for phagocytosis.
    Major Histocompatibility Complex (MHC) is a cell surface molecule which mediates interactions of leucocytes.

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  • 14. 

    Each chain in a B-Cell Receptor (BCR) is linked by a Hydrogen bond.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    Each chain is linked by a disulphide bridge.

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  • 15. 

    1. The cytokine IL-10, as produced by T-helper 2 cells inhibits macrophage activation.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    The Cytotoxic (CD8+) T-cell secretes the cytokine IL-10 which inhibits the action of Natural Killer Cells (NKC).

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  • 16. 

    The Cytotoxic (CD8+) T-cell secretes the cytokine IL-10 which enhances the action of Natural Killer Cells (NKC).

    • True

    • False

    Correct Answer
    A. False
    Explanation
    The Cytotoxic (CD8+) T-cell secretes the cytokine IL-10 which inhibits the action of Natural Killer Cells (NKC).

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  • 17. 

    T-cells originate in the Thymus as a T cell progenitor (precursor) from which other T cells derive.

    • True

    • False

    Correct Answer
    A. False
    Explanation
    T-cells originate in the Bone Marrow like all the cells of the immune system, and only migrate to the Thymus to differentiate and mature; hence T (Thymus) lymphocyte.

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  • 18. 

    The cytokine IL-10, as produced by T-helper 2 cells inhibits macrophage activation.

    • True

    • False

    Correct Answer
    A. True
    Explanation
    The statement is true because IL-10, which is produced by T-helper 2 cells, indeed inhibits macrophage activation. IL-10 is an anti-inflammatory cytokine that plays a crucial role in regulating the immune response. It acts by suppressing the production of pro-inflammatory cytokines and inhibiting the activation of macrophages, which are key players in the immune response. By inhibiting macrophage activation, IL-10 helps to control and dampen the immune response, preventing excessive inflammation and tissue damage.

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  • Current Version
  • Mar 22, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Dec 01, 2011
    Quiz Created by
    SwanseaGEMStuden
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