Pg Blazer - Online Test Series 10 - Pathology

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Quizzes Created: 37 | Total Attempts: 137,285
| Attempts: 2,169
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  • 1/10 Questions

    Finding on histopathological examination in liver in case of malaria is :

    • Microabscess formation
    • Kupffer‘s cell hyperplasia with macrophage infiltration around periportal area laden with pigments.
    • Non caseating granuloma
    • Non specific finding of neutrophilic infiltration
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About This Quiz

MCQ's in pathology. For more practice tests, go to PG Blazer Online Test Series

Medical Test Quizzes & Trivia

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  • 2. 

    True about Apoptosis are all except :

    • Inflammation is present

    • Chromosomal breakage

    • Clumping of chromatin

    • Cell shrinkage

    Correct Answer
    A. Inflammation is present
    Explanation
    Inflammation is absent in apoptosis. It is seen only in necrosis.

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  • 3. 

    Brain natriuretic peptide is degraded by

    • Neutral endopeptidase

    • Elastase

    • Collagenase

    • Omapatrilat

    Correct Answer
    A. Neutral endopeptidase
    Explanation
    BNP is degraded by neutral endopeptidase. Omapatrilat inhibits neutral endopeptidase. Hence it is useful in treatment of heart failure.

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  • 4. 

    Most common gene defect in Idiopathic Steroid Resistant Nephrotic Syndrome

    • ACE

    • NPHS 2

    • HOX ll

    • PAX

    Correct Answer
    A. NPHS 2
    Explanation
    NPHS 2 gene coding for the protein podocin (located in the slit diaphragm) is mutated in steroid resistant nephrotic syndrome.

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  • 5. 

    A diabetic patient is undergoing dialysis. Aspiration done around the knee joint would show,

    • Aβ2 microglobulin

    • AA

    • AL

    • Lactoferrin

    Correct Answer
    A. Aβ2 microglobulin
    Explanation
    Patients undergoing long term dialysis is prone to development of amyloidosis. The type of amyloid protein that gets deposited in this condition is Aβ2 microglobulin.

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  • 6. 

    What is the best method for confirming amyloidosis :

    • Colonoscopy

    • Sigmoidoscopy

    • Rectal biopsy

    • Tongue biopsy

    Correct Answer
    A. Rectal biopsy
    Explanation
    Sensitivity for diagnosis of amyloidosis in various biopsy sites:
    Rectal / gingival - 80%
    Abdominal fat aspirate - 70-80%
    Bone marrow - 50%

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  • 7. 

    All are B cell marker except :

    • CD-19

    • CD-21

    • CD-15

    • CD-22

    Correct Answer
    A. CD-15
    Explanation
    CD-15 is seen in neutrophils, eosinophils and monocytes.
    B cell markers are : CD 19, CD 20, CD 21, CD 22

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  • 8. 

    Michaelis Gutmann bodies are seen in

    • Xanthogranulomatous pyelonephritis

    • Malakoplakia

    • Nail patella syndrome

    Correct Answer
    A. Malakoplakia
    Explanation
    Michaelis-Gutmann bodies are concentrically layered basophilic inclusions found in the urinary tract. The size ranges from 2 to 10 μm in diameter. They are believed to be remnants of phagosomes mineralized by iron and calcium deposits. Histologic identification of M-G bodies are pathognomonic of malakoplakia.

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  • 9. 

    Non specific esterase is positive in all the categories of AML except

    • M3

    • M4

    • M5

    • M6

    Correct Answer
    A. M6
    Explanation
    Non specific esterase is characteristically seen in M4 and M5. It is also seen in some cases of M3 and M7.

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  • 10. 

    Least affected in Graft – Versus host reaction:

    • Skin

    • G.I.T

    • Liver

    • Lung

    Correct Answer
    A. Lung
    Explanation
    Any organ can be affected in GVH reaction. The most important is the involvement of immune system, skin, liver and intestines.

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  • Current Version
  • Mar 19, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Jun 14, 2011
    Quiz Created by
    Pgblazer
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