Mt4l4 Elhm Pathology Course (Exam 1)
.
- 1.Which of the following factors participates in the Formation of inflammatory fluid exudate:
- A.
Increased intravascular osmotic pressure
- B.
Lncreased vascular permeability
- C.
Decreased osmotic pressure of the interstitial tissue
- D.
Vasoconstriction
- E.
All of the above
- 2.Which oF the following is an effect of chemical mediators :
- A.
Increased vascular permeability
- B.
Chemolaxis
- C.
Fever
- D.
All of the above
- E.
None of the above
- 3.Which of the following is true about vascular stasis in acute inflammation:
- A.
Lt is mainly induced by vasoconstriction.
- B.
Lt mainly occurs after emigration of leucocytes
- C.
Lt may lead to thrombosis
- D.
AII of the above
- E.
None of the above
- 4.Which of the following statements is true about the cellular phase of acute inflammation:
- A.
Opsonins play an important role in the process of pavementing
- B.
Neutrophils and monocytes emigrate at the same time.
- C.
Emigration of leucocytes is followed by Ieucopenia
- D.
Giant cells are formed by fusion of neutrophils
- E.
Bacilli are more chernotactic to macrophages while cocci mainly attract neutrophils
- 5.Which of the following is true about fibrin:
- A.
Deposition of fibrin in inflammatory conditions is known as fibrosis
- B.
Fibrin plays important functions in inflammation & repair
- C.
Cellulitis is characterized by excess fibrin deposition
- D.
All of the above
- E.
None of the abovE
- 6.Which cf the following is true about chemotaxis:
- A.
This is diversion cf Ieucocytes out of the axial column of blood prior to their emigration
- B.
Typhoid bacilli are strongly chemotactic to neutrophils.
- C.
Complement components are important chemotactic factors
- D.
AlI of the above
- E.
None of the above
- 7.Which of the following statements is true for neutrophils:
- A.
They are the first cells to emigrate in acute inflammation
- B.
They are the most predominant cells in chronic inflammation.
- C.
The most important chemotactic factors for neutrophiis are derived from bacilii.
- D.
They efficiently engulf foreign bodies
- E.
They can give rise to giant cells
- 8.Which of the following is not a feature of acute inflammation:
- A.
Persistent vasoconstriction
- B.
Vasodilatation
- C.
Lncreased vascular permeability
- D.
Emigration of leucocytes
- E.
Vascular stasis.
- 9.Which of the following is not a function of fibrin:
- A.
Opsonization
- B.
Sealing of bleeding vessels
- C.
Facilitation of movement of inflammatory cells
- D.
Localization of inflammatory fields
- E.
Facilitation of movement of fibroblasts during repair
- 10.Which of the following cells engulf fibrin:
- A.
Neutrophils
- B.
Eosinophils
- C.
Macrophages
- D.
Lymphocytes
- E.
Plasma cells
- 11.Which of the following is true about activation of phospholipase C of phagocytic cells:
- A.
Lt provides the phagocytic cells with phospholipids
- B.
Lt provides the phagocytic cells with energy
- C.
Lt hydrolyses the release of calcium and enhances cell Mobility.
- D.
AIl of the above
- E.
None of the above.
- 12.Which of the following statements is true for hepatic steatosis :
- A.
May be caused by alcohol intake
- B.
May occur in cases of hepatitis C
- C.
May be followed by cirrhosis.
- D.
All of the above
- E.
None of the above
- 13.The following are features of apoptosis except:
- A.
Lt is always caused by irrità nts such as anoxia, bacteriai infections and alcohol.
- B.
Lt is characterized by fragmentation of nuclear DNA.
- C.
It is characterized by formation of cell membrane blebs.
- D.
Lt is characterized by transformation cf the affected cell into apoptotic bodies.
- E.
Phagocytosis of the apoptotic bodies is common.
- 14.Caseous necrosis is characterized by all of the following features except:
- A.
Cheese-like material
- B.
Commonly seen in tuberculous Iesions.
- C.
The structural outlines of the necrotic cells are preserved.
- D.
Lt represents partially iiquified coagulative necrosis.
- E.
Microscopically appears as amorphous eosinophilic granular debris.
- 15.AII of the following changes can be seen in necrotic cells except::
- A.
Pyknosis
- B.
Karyorrhexis
- C.
Mitosis
- D.
Karyolysis
- E.
Cytomegaly
- 16.Which of the following conditions is characterized by liquefactive necrosis
- A.
Lung infarction
- B.
Cerebral infarction
- C.
Pulmonary tuberculosis
- D.
AlI of the above
- E.
None of the above
- 17.Which of the following statements is true for dystrophic calcification :
- A.
It is due to hypercalcemia
- B.
Lt affects healthy tissues
- C.
Lt can be seen in tubeculosis.
- D.
Lt cormmonly occurs in teeth and bone
- E.
Lt is more common in arterial lhan venous thrombi
- 18.Which of the following statements is true for metastatic calcification
- A.
Lt may occur in cases of hyperparathyroidism.
- B.
It is seen in metastatic tumors.
- C.
Calcified thrombi represent a type of metastatic calcitication
- D.
All of the above
- E.
None of the above
- 19.Which of the following statements is not true tor amyloidosis:
- A.
Amyloid is predominantly a fibril protein.
- B.
Macrophages may play an important role in systemic amyloidosis
- C.
Sudan lll and osmic acid can specifically stain amyloid
- D.
Amyloid is mainly deposited within the walls of small blood vessels
- E.
Amyloidosis may Iead to Addison's disease.
- 20.The following are causes of systemic amyloidosis except:
- A.
Acute suppurations
- B.
Tuberculosis
- C.
Ulcerative colitis.
- D.
Rheumatoid arthritis
- E.
Mlultiple myeloma.
- 21.Which of the following types of amyloid affection produces the most serious effects:
- A.
Amyloid sago spleen
- B.
Hepatic amyloidosis
- C.
Renal amyloidosis
- D.
Amyloid diffuse spleen
- E.
Cutaneous amyloidosis
- 22.In all of the following conditions the amyloid fibril protein is AA except:
- A.
Ulcerative colitis
- B.
Multiple myeloma
- C.
Tuberculosis
- D.
Chronic Iung abscess
- E.
Hodgkin's disoase.
- 23.Which of the following is true about amyloid deposited within m medullary carcinoma of thyroid:
- A.
The amyloid protein is secreted by macrophages within the thyroid gland.
- B.
The amyloid protein is produced by tumor cells .
- C.
Lt may be accompanied by renal or hepatic amyloidosis.
- D.
The amyloid protein is AL
- E.
None of the above
- 24.Which of the following conditions associated with abnormal melanin deposition :
- A.
Neurofibromatosis
- B.
Brown atrophy of the heart
- C.
Melanosis coli
- D.
Leukoderma
- E.
All of the above
- 25.If the following features of the acute inflammatory reaction were placed in chronological order which would come fourth as regard vascular phase ?
- A.
Arteriolar contraction
- B.
Blood flow slows.
- C.
Dilatation of arterioles.
- D.
Emigration of leucocytes from blood vessels.
- E.
Protein rich fluid escapes from blood vessels.
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