Pg Blazer - Online Test Series 24 - Pathology

10 Questions | By Pgblazer | Updated: Mar 19, 2022 | Attempts: 1495

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Subject wise MCQ test - Pathology. For more online practice tests, go to PG Blazer Online Test Series

Questions and Answers

1.

Which of the following pigments are involved in free radical injury
- A.
  
  Lipofuscin
- B.
  
  Melanin
- C.
  
  Bilirubin
- D.
  
  Hematin
2.

Why fetal cells continue to divide but terminally differentiated adult cells do not divide
- A.
  
  There are many cyclin inhibitors which prevent cells from entering into S phase in adult
- B.
  
  Phosphatase is absent in fetal cells
- C.
  
  Proteinase is absent in fetal cells
- D.
  
  Absence of CD kinase
3.

Toll like receptors, recognize bacterial products and stimulates immune response by,
- A.
  
  Perforin and granzyme mediated apoptosis
- B.
  
  FADD ligand apoptosis
- C.
  
  Transcription of nuclear factor mediated by NFKB which recruits cytokines
- D.
  
  Cyclin
4.

C-C beta chemokine includes
- A.
  
  LL-8
- B.
  
  Eotaxin
- C.
  
  Lymphotactin
- D.
  
  Fractalkine
5.

In acute inflammation due to the contraction of endothelial cell cytoskeleton, which of the following results
- A.
  
  Delayed transient increase in permeability
- B.
  
  Early transient increase
- C.
  
  Delayed permanent increase
- D.
  
  Early permanent increase
6.

Most pathognomonic sign of irreversible cell injury
- A.
  
  Amorphous densities in mitochondria
- B.
  
  Swelling of the cell membrane
- C.
  
  Ribosomes detached from endoplasmic reticulum
- D.
  
  Clumping of nuclear chromatin
7.

The most common gene defect in idiopathic steroid resistant nephrotic syndrome
- A.
  
  ACE
- B.
  
  NPHS 2
- C.
  
  HOX 1
- D.
  
  PAX
8.

An undifferentiated malignant tumour on immunohistochemical stain shows cytoplasmic positivity of most of the tumor cells for cytokeratin. The most probable diagnosis of the tumor is:
- A.
  
  Sarcoma
- B.
  
  Lymphoma
- C.
  
  Carcinoma
- D.
  
  Malignant Melanoma
9.

A 50-year-old male presented with signs and symptoms of restrictive heart disease. A right ventricular endo-myocardial biospy revealed deposition of extracellular eosionophilic hyaline material. On transmission electron microscopy, this material is most likely to reveal the presence of:
- A.
  
  Non branching filaments of indefinitive length
- B.
  
  Cross banded fibres with 67 m periodicity
- C.
  
  Weber Palade bodies
- D.
  
  Concentric whorls of lamellar structures
10.

Sections from a solid-cystic uniliateral ovarian tumor in a 30-year old female show a tumor composed of diffuse sheets of small cells with doubtful nuclear grooving and scanty cytoplasm. No Call-Exner bodies are seen. The ideal immunohistochemistry panel would include:
- A.
  
  Vimentin, epithelial membrane antigen, inhibin, CD99
- B.
  
  Desmin, S-100 protein, smooth muscle antigen, cytokeratin
- C.
  
  Chromogranin, CD45, CD99, CD20
- D.
  
  CD 3, chromagranin, CD 45, synaptophysin