Pg Blazer - Online Test Series 24 - Pathology
Subject wise MCQ test - Pathology. For more online practice tests, go to PG Blazer Online Test Series
- 1.Which of the following pigments are involved in free radical injury
- A.
Lipofuscin
- B.
Melanin
- C.
Bilirubin
- D.
Hematin
- 2.Why fetal cells continue to divide but terminally differentiated adult cells do not divide
- A.
There are many cyclin inhibitors which prevent cells from entering into S phase in adult
- B.
Phosphatase is absent in fetal cells
- C.
Proteinase is absent in fetal cells
- D.
Absence of CD kinase
- 3.Toll like receptors, recognize bacterial products and stimulates immune response by,
- A.
Perforin and granzyme mediated apoptosis
- B.
FADD ligand apoptosis
- C.
Transcription of nuclear factor mediated by NFKB which recruits cytokines
- D.
Cyclin
- 4.C-C beta chemokine includes
- A.
LL-8
- B.
Eotaxin
- C.
Lymphotactin
- D.
Fractalkine
- 5.In acute inflammation due to the contraction of endothelial cell cytoskeleton, which of the following results
- A.
Delayed transient increase in permeability
- B.
Early transient increase
- C.
Delayed permanent increase
- D.
Early permanent increase
- 6.Most pathognomonic sign of irreversible cell injury
- A.
Amorphous densities in mitochondria
- B.
Swelling of the cell membrane
- C.
Ribosomes detached from endoplasmic reticulum
- D.
Clumping of nuclear chromatin
- 7.The most common gene defect in idiopathic steroid resistant nephrotic syndrome
- A.
ACE
- B.
NPHS 2
- C.
HOX 1
- D.
PAX
- 8.An undifferentiated malignant tumour on immunohistochemical stain shows cytoplasmic positivity of most of the tumor cells for cytokeratin. The most probable diagnosis of the tumor is:
- A.
Sarcoma
- B.
Lymphoma
- C.
Carcinoma
- D.
Malignant Melanoma
- 9.A 50-year-old male presented with signs and symptoms of restrictive heart disease. A right ventricular endo-myocardial biospy revealed deposition of extracellular eosionophilic hyaline material. On transmission electron microscopy, this material is most likely to reveal the presence of:
- A.
Non branching filaments of indefinitive length
- B.
Cross banded fibres with 67 m periodicity
- C.
Weber Palade bodies
- D.
Concentric whorls of lamellar structures
- 10.Sections from a solid-cystic uniliateral ovarian tumor in a 30-year old female show a tumor composed of diffuse sheets of small cells with doubtful nuclear grooving and scanty cytoplasm. No Call-Exner bodies are seen. The ideal immunohistochemistry panel would include:
- A.
Vimentin, epithelial membrane antigen, inhibin, CD99
- B.
Desmin, S-100 protein, smooth muscle antigen, cytokeratin
- C.
Chromogranin, CD45, CD99, CD20
- D.
CD 3, chromagranin, CD 45, synaptophysin
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