NCLEX Pharmacology Quiz 6 (10 Items)

10 Questions | By Santepro | Last updated: Mar 21, 2022 | Total Attempts: 1491

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All questions are shown, but the results will only be given after you’ve finished the quiz. You are given 1 minute per question, a total of 10 minutes in this quiz.

Questions and Answers

1.

The primary complication of a central venous access device (CVAD) is:
- A.
  
  Thrombus formation in the vein.
- B.
  
  Pain and discomfort.
- C.
  
  Infection.
- D.
  
  Occlusion of the catheter as the result of an intra-lumen clot.
2.

Nurse Blessy is doing some patient education related to a patient’s central venous access device. Which of the following statements will the nurse make to the patient?
- A.
  
  “These type of devices are essentially risk free.”
- B.
  
  “These devices seldom work for more than a week or two necessitating replacement.”
- C.
  
  “The dressing should only the changed by your doctor.”
- D.
  
  “Heparin in instilled into the lumen of the catheter to decrease the risk of clotting.”
3.

The chemotherapeutic DNA alkylating agents such as nitrogen mustards are effective because they:
- A.
  
  Cross-link DNA strands with covalent bonds between alkyl groups on the drug and guanine bases on DNA.
- B.
  
  Have few. if any. side effects.
- C.
  
  Are used to treat multiple types of cancer.
- D.
  
  Are cell cycle-specific agents.
4.

Hormonal agents are used to treat some cancers. An example would be:
- A.
  
  Thyroxine to treat thyroid cancer.
- B.
  
  ACTH to treat adrenal carcinoma.
- C.
  
  Estrogen antagonists to treat breast cancer.
- D.
  
  Glucagon to treat pancreatic carcinoma.
5.

Chemotherapeutic agents often produce a certain degree of myelosuppression including leukopeniA. Leukopenia does not present immediately but is delayed several days to weeks because:
- A.
  
  The patient’s hemoglobin and hematocrit are normal.
- B.
  
  Red blood cells are affected first.
- C.
  
  Folic acid levels are normal.
- D.
  
  The current white cell count is not affected by chemotherapy.
6.

Currently. there is no way to prevent myelosuppression. However. there are medications available to elicit a more rapid bone marrow recovery. An example is:
- A.
  
  Epoetin alfa (Epogen. Procrit).
- B.
  
  Glucagon.
- C.
  
  Fenofibrate (Tricor).
- D.
  
  Lamotrigine (Lamictal).
7.

Estrogen antagonists are used to treat estrogen hormone-dependent cancer. such as breast carcinomA. Androgen antagonists block testosterone stimulation of androgen-dependent cancers. An example of an androgen-dependent cancer would be:
- A.
  
  Prostate cancer.
- B.
  
  Thyroid cancer.
- C.
  
  Renal carcinoma.
- D.
  
  Neuroblastoma.
8.

Serotonin release stimulates vomiting following chemotherapy. Therefore. serotonin antagonists are effective in preventing and treating nausea and vomiting related to chemotherapy. An example of an effective serotonin antagonist antiemetic is:
- A.
  
  Ondansetron (Zofran).
- B.
  
  Fluoxetine (Prozac).
- C.
  
  Paroxetine (Paxil).
- D.
  
  Sertraline (Zoloft).
9.

Methotrexate. the most widely used antimetabolite in cancer chemotherapy does not penetrate the central nervous system (CNS). To treat CNS disease this drug must be administered:
- A.
  
  Intravenously.
- B.
  
  Subcutaneously.
- C.
  
  Intrathecally.
- D.
  
  By inhalation.
10.

Methotrexate is a folate antagonist. It inhibits enzymes required for DNA base synthesis. To prevent harm to normal cells. a fully activated form of folic acid known as leucovorin (folinic acid; citrovorum factor) can be administered. Administration of leucovorin is known as:
- A.
  
  Induction therapy.
- B.
  
  Consolidation therapy.
- C.
  
  Pulse therapy.
- D.
  
  Rescue therapy.