Molecular Genetics: Eukaryotic Protein Synthesis

17 Questions | Total Attempts: 56

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Molecular Genetics: Eukaryotic Protein Synthesis

Questions based on Lecture 1. Of Molecular Genetics: Protein Synthesis with Dr Sealy-Lewis.


Questions and Answers
  • 1. 
    Which stage of protein synthesis makes promoting Eukarotic genes in Prokaryotes difficult?
    • A. 

      Transcription

    • B. 

      Intiation

    • C. 

      Elongation

    • D. 

      Termination

  • 2. 
    Prokaryotic intiation phase requires?
    • A. 

      5'Cap

    • B. 

      Removal of Introns

    • C. 

      Removal of Extrons

    • D. 

      Shine-Dalgarno sequence

    • E. 

      Addition of Poly AAA tail

  • 3. 
    Eukaryotic intiation phase requires?
    • A. 

      Shine-Dalgarno Sequence

    • B. 

      Removal of Introns

    • C. 

      5' Cap

    • D. 

      Removal of Exons

    • E. 

      Addition of Poly AAA tail

  • 4. 
    What are the functions of the 5' Cap?
    • A. 

      Regulation of nuclear export

    • B. 

      Prevention of degradation by exonucleases

    • C. 

      Promotion of translation

    • D. 

      Promotion of 5' intron excision

    • E. 

      Tag for degradation

    • F. 

      Ligation of exons

    • G. 

      Promotion of degradation by exonucleases

  • 5. 
    Intiation in prokaryotes requires only 3 factors whereas eukaryotes use 13?
    • A. 

      True

    • B. 

      False

  • 6. 
    AUG is the triplet code for Cysteine?
    • A. 

      True

    • B. 

      False

  • 7. 
    What are the stop codons?
    • A. 

      UAG

    • B. 

      UAA

    • C. 

      UGA

    • D. 

      AUG

    • E. 

      AAG

  • 8. 
    What is the start codon?
    • A. 

      AUG - Methionine

    • B. 

      ACA - Proline

    • C. 

      AGU - Serine

    • D. 

      AAU - Asparagine

  • 9. 
    Elongation requires GTP?
    • A. 

      True

    • B. 

      False

  • 10. 
    Imet stands for?
    • A. 

      Intiator methionine

    • B. 

      Inducer methionine

    • C. 

      Indigo methionine

  • 11. 
    Which of the following is a prokaryotic inhibitor?
    • A. 

      Cycloheximide

    • B. 

      Ricin

    • C. 

      Abrin

    • D. 

      Streptomycin

  • 12. 
    Which of the following is an Eukaryotic inhibitor?
    • A. 

      Ricin

    • B. 

      Erythromycin

    • C. 

      Tetracyclin

    • D. 

      Streptomycin

  • 13. 
    Polycistronic mRNA is mRNA that encodes for multiple different proteins. 
    • A. 

      True

    • B. 

      False

  • 14. 
    Ubiquitin tagging prevents degradation by proteosomes?
    • A. 

      True

    • B. 

      False

  • 15. 
    Which of the following statements are true regarding the start codon?
    • A. 

      It is found in the Kozak sequence

    • B. 

      It is the first codon in the scanning process

    • C. 

      It codes for Methionine

    • D. 

      It codes for Amber

    • E. 

      It can be up to 1000 bases from the cap

  • 16. 
    Ribosomes are made of ________
    • A. 

      60s + 40s subunits

    • B. 

      40s + 40s subunits

    • C. 

      20s + 40s subunits

  • 17. 
    Scanning is the process by which ___________
    • A. 

      The 40s subunit finds the stop codon

    • B. 

      The 40s subunit finds the start codon

    • C. 

      The 40s subunit finds an ATP source

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