Review quiz on chlamydiae and rickettsiae
Motile
Gram positive
Obligate extracellular pathogens
Biphasic morphology
Contain murein
Contain mycolic acid
Has LPS
No cytoplasmic membrane
Rickettsia
Chlamydia
Mycoplasma
A & B
A variant of the rickettsia bacteria
May be present with N. gonorrhea infection
Occurs in children and may lead to blindness
Common cause of pneumonia
Rickettsia
Neisseria
Chlamydiae
Clostridium
Previous rickettsial infection
C. trachomatis infection
M. tuberculosis infection
Previous C. pneumoniae infection
Have a 2-form developmental cycle
Spread by arthropod vectors
Affect blood vessels
Murein in cell walls
Developmental form of Rickettsia
Noninfectious and found intracellularly in repiratory and GI mucosa
Metabolically active and does not attach to epithelium
Forms fused inclusions except for C. pneumonia
Developmental form of rickettsia
Lives outside of inclusions by binding epithelial cells
Replicates by binary fission
Are infectious
Straw like appendages similar to type III secretion system
Transform into elementary body and escape phagosome
Release siderophores and hydrilipases
None of the above
RBs are smaller and consume less nutrients
Produce protease to delay cell death
Intracellular invasion reduces inflammation
All of the above
Cell mediated host response to serovars
Bacterial release of protease that cause cell lysis
Reiter's syndrome in women
Serovars are immobile and no exudate is present
C. pneumoniae
Rickettsia
LGV biovariant
All of the above
C. Trachomatis
C. Pneumoniae
Rickettsia
Q fever
Direct fluorescent assay
Culture from exudate
Nucleic amplification of urine
A & C
All of the above
True
False
Azythromizin 7 days
Doxycycline 7 days
Erythromycin
3 weeks of therapy
Disseminate via the lymphatic system
Avoid being engulfed by cells
Multiply in the lumen of the blood vessels
Attach to cell membrane of vascular endothelium
Release pore forming toxins
Type III secretion system
No cellular damage
Remain extracellularly
Affects the appearance of the skin
Multiply in phagosomes
Affects blood vessels
Can be cleared by strong host defense
Lyme disease
Typhus fever
Q fever
Rickettsia
Typhus fever
Q fever
Ehrliciosis
Anaplasmosis
E. chaffeensis
E. ewingii
Anaplasma phagocytophilum
A & B
B & C
Fever
Rash
Tick bite
High titers
Tetracylcine
Doxycycline
Fluoroquinolones
Trimethoprim
Wait!
Here's an interesting quiz for you.