Micro - Chlamydiae And Rickettsiae

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Review quiz on chlamydiae and rickettsiae


Questions and Answers
  • 1. 
    Which of the following describes both chlamydiae and rickettsiae
    • A. 

      Motile

    • B. 

      Gram positive

    • C. 

      Obligate extracellular pathogens

    • D. 

      Biphasic morphology

  • 2. 
    Which of the following describes the membranes and cell wall of chlamydiae?
    • A. 

      Contain murein

    • B. 

      Contain mycolic acid

    • C. 

      Has LPS

    • D. 

      No cytoplasmic membrane

  • 3. 
    Which of the following bacteria are auxotropic and need ATP and amino acids from their host
    • A. 

      Rickettsia

    • B. 

      Chlamydia

    • C. 

      Mycoplasma

    • D. 

      A & B

  • 4. 
    Lymphogranuloma venereum can be described as which of the following
    • A. 

      A variant of the rickettsia bacteria

    • B. 

      May be present with N. gonorrhea infection

    • C. 

      Occurs in children and may lead to blindness

    • D. 

      Common cause of pneumonia

  • 5. 
    Trachoma, an ocular disease affecting children and a possible cause of blindness is linked to which of the following bacteria?
    • A. 

      Rickettsia

    • B. 

      Neisseria

    • C. 

      Chlamydiae

    • D. 

      Clostridium

  • 6. 
    A patient presents with coronary artery disease. Which of the following findings may be expected?
    • A. 

      Previous rickettsial infection

    • B. 

      C. trachomatis infection

    • C. 

      M. tuberculosis infection

    • D. 

      Previous C. pneumoniae infection

  • 7. 
    Which of the following similarities exist between rickettsia and chlamydiae
    • A. 

      Have a 2-form developmental cycle

    • B. 

      Spread by arthropod vectors

    • C. 

      Affect blood vessels

    • D. 

      Murein in cell walls

  • 8. 
    Which of the following describes an Elementary body?
    • A. 

      Developmental form of Rickettsia

    • B. 

      Noninfectious and found intracellularly in repiratory and GI mucosa

    • C. 

      Metabolically active and does not attach to epithelium

    • D. 

      Forms fused inclusions except for C. pneumonia

  • 9. 
    Which of the following describes a reticulate body?
    • A. 

      Developmental form of rickettsia

    • B. 

      Lives outside of inclusions by binding epithelial cells

    • C. 

      Replicates by binary fission

    • D. 

      Are infectious

  • 10. 
    Chlamydiae obtain nutrients through which of the following methods?
    • A. 

      Straw like appendages similar to type III secretion system

    • B. 

      Transform into elementary body and escape phagosome

    • C. 

      Release siderophores and hydrilipases

    • D. 

      None of the above

  • 11. 
    Which of the following methods are used by the Chlamydia in persistence phase?
    • A. 

      RBs are smaller and consume less nutrients

    • B. 

      Produce protease to delay cell death

    • C. 

      Intracellular invasion reduces inflammation

    • D. 

      All of the above

  • 12. 
    C. trachomatis damage is linked  to which of the following?
    • A. 

      Cell mediated host response to serovars

    • B. 

      Bacterial release of protease that cause cell lysis

    • C. 

      Reiter's syndrome in women

    • D. 

      Serovars are immobile and no exudate is present

  • 13. 
    Herpes like lesions are most likely due to which of the followin
    • A. 

      C. pneumoniae

    • B. 

      Rickettsia

    • C. 

      LGV biovariant

    • D. 

      All of the above

  • 14. 
    Which bacteria infects cells involved in atherogenesis?
    • A. 

      C. Trachomatis

    • B. 

      C. Pneumoniae

    • C. 

      Rickettsia

    • D. 

      Q fever

  • 15. 
    Which of the following methods can sufficiently diagnose C. trachomatis
    • A. 

      Direct fluorescent assay

    • B. 

      Culture from exudate

    • C. 

      Nucleic amplification of urine

    • D. 

      A & C

    • E. 

      All of the above

  • 16. 
    C. Pneumoniae can be distinguished from  M. Pneumoniae because M. Pneumoniae is positive for cold agglutinins
    • A. 

      True

    • B. 

      False

  • 17. 
    A Pt. with non-flulike symptoms reports to the ER for  C. pneumonia. After running routine tests you find out she is pregnant, What is the best drug therapy?
    • A. 

      Azythromizin 7 days

    • B. 

      Doxycycline 7 days

    • C. 

      Erythromycin

    • D. 

      3 weeks of therapy

  • 18. 
    After a host is inoculated by a tick bite, which of the following actions are taken by Rickettsia?
    • A. 

      Disseminate via the lymphatic system

    • B. 

      Avoid being engulfed by cells

    • C. 

      Multiply in the lumen of the blood vessels

    • D. 

      Attach to cell membrane of vascular endothelium

  • 19. 
    Which of the following describes rickettsia ability to infect endothelial cells?
    • A. 

      Release pore forming toxins

    • B. 

      Type III secretion system

    • C. 

      No cellular damage

    • D. 

      Remain extracellularly

  • 20. 
    Which of the following separates rickettsia from chlamydia
    • A. 

      Affects the appearance of the skin

    • B. 

      Multiply in phagosomes

    • C. 

      Affects blood vessels

    • D. 

      Can be cleared by strong host defense

  • 21. 
    Pt. presents with R. prowazekii infection. Which of the following disease may they develop?
    • A. 

      Lyme disease

    • B. 

      Typhus fever

    • C. 

      Q fever

    • D. 

      Rickettsia

  • 22. 
    Which of the following does not need a living vector for transmission?
    • A. 

      Typhus fever

    • B. 

      Q fever

    • C. 

      Ehrliciosis

    • D. 

      Anaplasmosis

  • 23. 
    Which of the following infects neutrophils
    • A. 

      E. chaffeensis

    • B. 

      E. ewingii

    • C. 

      Anaplasma phagocytophilum

    • D. 

      A & B

    • E. 

      B & C

  • 24. 
    Which of the following would rule out Q fever
    • A. 

      Fever

    • B. 

      Rash

    • C. 

      Tick bite

    • D. 

      High titers

  • 25. 
    The drug of choice for rickettsial infections is which of the following?
    • A. 

      Tetracylcine

    • B. 

      Doxycycline

    • C. 

      Fluoroquinolones

    • D. 

      Trimethoprim

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