Micro - Chlamydiae And Rickettsiae
Review quiz on chlamydiae and rickettsiae
- 1.Which of the following describes both chlamydiae and rickettsiae
- A.
Motile
- B.
Gram positive
- C.
Obligate extracellular pathogens
- D.
Biphasic morphology
- 2.Which of the following describes the membranes and cell wall of chlamydiae?
- A.
Contain murein
- B.
Contain mycolic acid
- C.
Has LPS
- D.
No cytoplasmic membrane
- 3.Which of the following bacteria are auxotropic and need ATP and amino acids from their host
- A.
Rickettsia
- B.
Chlamydia
- C.
Mycoplasma
- D.
A & B
- 4.Lymphogranuloma venereum can be described as which of the following
- A.
A variant of the rickettsia bacteria
- B.
May be present with N. gonorrhea infection
- C.
Occurs in children and may lead to blindness
- D.
Common cause of pneumonia
- 5.Trachoma, an ocular disease affecting children and a possible cause of blindness is linked to which of the following bacteria?
- A.
Rickettsia
- B.
Neisseria
- C.
Chlamydiae
- D.
Clostridium
- 6.A patient presents with coronary artery disease. Which of the following findings may be expected?
- A.
Previous rickettsial infection
- B.
C. trachomatis infection
- C.
M. tuberculosis infection
- D.
Previous C. pneumoniae infection
- 7.Which of the following similarities exist between rickettsia and chlamydiae
- A.
Have a 2-form developmental cycle
- B.
Spread by arthropod vectors
- C.
Affect blood vessels
- D.
Murein in cell walls
- 8.Which of the following describes an Elementary body?
- A.
Developmental form of Rickettsia
- B.
Noninfectious and found intracellularly in repiratory and GI mucosa
- C.
Metabolically active and does not attach to epithelium
- D.
Forms fused inclusions except for C. pneumonia
- 9.Which of the following describes a reticulate body?
- A.
Developmental form of rickettsia
- B.
Lives outside of inclusions by binding epithelial cells
- C.
Replicates by binary fission
- D.
Are infectious
- 10.Chlamydiae obtain nutrients through which of the following methods?
- A.
Straw like appendages similar to type III secretion system
- B.
Transform into elementary body and escape phagosome
- C.
Release siderophores and hydrilipases
- D.
None of the above
- 11.Which of the following methods are used by the Chlamydia in persistence phase?
- A.
RBs are smaller and consume less nutrients
- B.
Produce protease to delay cell death
- C.
Intracellular invasion reduces inflammation
- D.
All of the above
- 12.C. trachomatis damage is linked to which of the following?
- A.
Cell mediated host response to serovars
- B.
Bacterial release of protease that cause cell lysis
- C.
Reiter's syndrome in women
- D.
Serovars are immobile and no exudate is present
- 13.Herpes like lesions are most likely due to which of the followin
- A.
C. pneumoniae
- B.
Rickettsia
- C.
LGV biovariant
- D.
All of the above
- 14.Which bacteria infects cells involved in atherogenesis?
- A.
C. Trachomatis
- B.
C. Pneumoniae
- C.
Rickettsia
- D.
Q fever
- 15.Which of the following methods can sufficiently diagnose C. trachomatis
- A.
Direct fluorescent assay
- B.
Culture from exudate
- C.
Nucleic amplification of urine
- D.
A & C
- E.
All of the above
- 16.C. Pneumoniae can be distinguished from M. Pneumoniae because M. Pneumoniae is positive for cold agglutinins
- A.
True
- B.
False
- 17.A Pt. with non-flulike symptoms reports to the ER for C. pneumonia. After running routine tests you find out she is pregnant, What is the best drug therapy?
- A.
Azythromizin 7 days
- B.
Doxycycline 7 days
- C.
Erythromycin
- D.
3 weeks of therapy
- 18.After a host is inoculated by a tick bite, which of the following actions are taken by Rickettsia?
- A.
Disseminate via the lymphatic system
- B.
Avoid being engulfed by cells
- C.
Multiply in the lumen of the blood vessels
- D.
Attach to cell membrane of vascular endothelium
- 19.Which of the following describes rickettsia ability to infect endothelial cells?
- A.
Release pore forming toxins
- B.
Type III secretion system
- C.
No cellular damage
- D.
Remain extracellularly
- 20.Which of the following separates rickettsia from chlamydia
- A.
Affects the appearance of the skin
- B.
Multiply in phagosomes
- C.
Affects blood vessels
- D.
Can be cleared by strong host defense
- 21.Pt. presents with R. prowazekii infection. Which of the following disease may they develop?
- A.
Lyme disease
- B.
Typhus fever
- C.
Q fever
- D.
Rickettsia
- 22.Which of the following does not need a living vector for transmission?
- A.
Typhus fever
- B.
Q fever
- C.
Ehrliciosis
- D.
Anaplasmosis
- 23.Which of the following infects neutrophils
- A.
E. chaffeensis
- B.
E. ewingii
- C.
Anaplasma phagocytophilum
- D.
A & B
- E.
B & C
- 24.Which of the following would rule out Q fever
- A.
Fever
- B.
Rash
- C.
Tick bite
- D.
High titers
- 25.The drug of choice for rickettsial infections is which of the following?
- A.
Tetracylcine
- B.
Doxycycline
- C.
Fluoroquinolones
- D.
Trimethoprim
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