This USMLE Microbiology Exam Practice Test assesses key knowledge in medical microbiology, focusing on diseases, bacterial characteristics, and clinical scenarios. It prepares learners for real-world medical challenges and USMLE certification.
Protein A-mediated opsonization block
Bacterial and human epitope homology
Immune complex deposition
Exotoxin-induced T-cell receptor activation
Coronary artery aneurysm formation
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Dental extraction
Skin biopsy
Sinus drainage
Nasal polypectomy
Cystoscopy
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A 34-year-old female with known mitral stenosis develops low-grade fevers and negative blood cultures
A 45-year-old male complains of fatigue and exertional dyspnea three weeks after tooth extraction
A 62-year-old female has a persistent fever after being diagnosed with colon cancer
A 64-year-old male with repeatedly negative blood cultures has small mitral vegetation on transesophageal echocardiogram
A 29-year-old male with a persistent fever has tricuspid vegetations and tricuspid regurgitation on transthoracic echocardiogram
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Glomerulonephritis
Sarcoidosis
Erythema nodosum
Migratory polyarthritis
Anterior uveitis
Dental caries
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Endothelial surface glycoproteins
Subendothelial collagen
Subendothelial glycosaminoglycans
Circulating heparins
Fibrin-platelet aggregates
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Expensive antibiotic requirement
Nephritic disease
Deaths caused by diarrhea
Bronchial asthma hospitalizations
Cardiac surgeries
Vaccination needs
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Penicillin G
Nafcillin
Vancomycin
Ciprofloxacin
Erythromycin
Ceftriaxone
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Catalase negative
Coagulase negative
Mannitol fermenting
Novobiocin resistance
Yellow pigment production
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LgA against adhesion proteins
Opsonizing lgM
Complement-fixing lgM
Immobilizing lgG
LgG against circulating proteins
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Prevent viral attachment to target cells
Inhibit viral protease activity
Incorporate into newly replicated viral DNA
Prevent virion release from infected cells
Up-regulate interferon synthesis in infected cells
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Catalase positivity
Growth in 6.5% NaCl
Bile solubility
Bacitracin sensitivity
Optochin sensitivity
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Gardnerella vaginalis
Neisseria gonorrhoeae
Trichomonas vaginalis
Treponema pallidum
Herpes simplex virus
Molluscum contagiosum
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Antigenic mimicry
Low molecular weight
Non-protein structure
Antigenic variation
Local immunosuppression
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Enrichment
Differential
Synthetic
Selective
Reducing
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Joint pain and eye redness
Fatigue and heart murmurs
Face puffiness and dark urine
Bilateral facial nerve palsy
Abdominal pain and jaundice
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Decreased thickness of the vaginal epithelium
Decreased glycogen concentration in the vaginal epithelium
Decreased number of Gram-positive bacteria in the vagina
Increased alkaline secretions by the cervical mucosa
Depressed T-lymphocyte response to mucosal stimuli
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Capsule
Heat-labile enterotoxin
O antigen
Fimbrial antigen
Lipid A
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Mast cells and eosinophils
Basophils and macrophages
Neutrophils and B lymphocytes
Macrophages and T lymphocytes
Platelets and mast cells
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Small intestine
Colon
Urinary tract
Biliary tree
Lungs
Oropharynx
Skin
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Capsule
Heat-stable exotoxin
O antigen
Fimbrial antigen
Lipid A
Flagellar antigen
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Escherichia coli
Pseudomonas aeruginosa
Klebsiella pneumoniae
Staphylococcus saprophyticus
Enterococcus cloacae
Ureaplasma urealyticum
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Endometrial hyperplasia
Hydatidiform mole
Ovarian cancer
Polycystic ovary syndrome
Infertility
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Coagulase positive
Hemolytic
Novobiocin resistant
DNase positive
Yellow pigment producer
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Hyaluronate
Protein M
Streptolysin O
DNase
Streptokinase
Teichoic acid
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Haemophilus ducreyi
K!ebsiella inguinale
Herpes simplex virus
Treponema pallidum
Chlamydia trachomatis
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Methotrexate therapy
Proper sore throat treatment
Timely vaccination
Barrier contraception
Avoiding intravenous drug abuse
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Klebsiella pneumoniae
Samonella typhi
Salmonella enteritidis
Campylobacter jejuni
Shigella dysenteriae
Proteus mirabilis
Yersinia enterocolitica
Haemophilus influenzae
Vibrio cholerae
Streptococcus pyogenes
Streptococcus pneumoniae
Escherichia coli
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Ulcer exudate microscopy after Gram staining
Ulcer exudate microscopy with darkfield illumination
Ulcer exudate cultures on enrichment media
Blood cultures on differential media
Antitoxin detection in the serum
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Intestinal invasion
'Stacked-brick' intestinal adhesion
Shiga-like toxin
Cholera-like toxin
Endotoxin release
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Escherichia coli
Klebsiella pneumoniae
Salmonela typhi
Salmonella enteritidis
Campylobacter fetus
Proteus mirabilis
Yersinia enterocolitica
Haemophilus inffuenzae
Helicobacter pylori
Vibrio cholerae
Streptococcus pyogenes
Streptococcus pneumoniae
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Exotoxin formed prior to ingestion
Exotoxin formed after ingestion
Endotoxin
Bacterial invasion of gut mucosa
Parasitic infection
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Cell-mediated immunity
Mucosal lgA antibodies
Gastric acidity
Intestinal biomass
Rapid gastrointestinal transit
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Mitochondrial energy production
Cytoskeleton integrity
Apical ion transport
Ribosomal protein synthesis
Cell membrane integrity
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Patients previously exposed to the bacteria
Patients with chronic pancreatitis
Patients on omeprazole treatment
Patients with chronic hepatitis
Patients with peptic ulcer disease
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Bronchiectasis
Pulmonary fibrosis
Congenital heart disease
Chronic hepatitis
Duodenal ulcer
Acute pancreatitis
Chronic diarrhea
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Exotoxin production
Mucosal invasion
Intestinal colonization
Bacteremia
Proliferation in lymph nodes
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Staphylococcus aureus
Shigella
Campylobacter
Bacillus cereus
Vibrio parahemolyticus
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Stool for bacterial toxins
Blood for liver enzymes
Blood for viral titers
Urine for glucose and ketones
Urine for amino acids
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Activate adenylate cyclase
Activate guanylate cyclase
Inactivate ribosomal subunits
Inactivate EF-2
Disrupt the cellular cytoskeleton
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Shigella dysenteriae
Salmonela typhi
Pseudomonas aeruginosa
Proteus mirabilis
Vibrio cholerae
Clostridium difficile
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Recent travel to Mexico
Missed vaccination
Antibiotic therapy
Gastritis prophylaxis
Consumption of home-canned foods
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Shigella nexneri
Vibrio cholerae
Vibrio parahaemolyticus
Clostridium perfringens
Enterotoxigenic E coli
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Mucus and some epithelial cells
Many leukocytes, neutrophils predominant
Many leukocytes, eosinophils predominant
Many leukocytes, lymphocytes predominant
Many erythrocytes and some leukocytes
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Aplastic anemia
Coronary artery aneurysm
Encephalitis
Orchitis
Rheumatic fever
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Transformation permitting capsule formation
Bacterial conjugation permitting pili expression
Phage conversion permitting exotoxin production
Chromosomal mutation permitting endotoxin production
Environmental influences permitting toxin synthesis
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Widespread T-cell activation
Blockade of neurotransmitter release
Activation of electrolyte transport
Impairment of protein synthesis
Cellular membrane disruption
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Antibiotic therapy
Active immunization
Passive immunization
Adequate hydration
Anti-inflammatory medications
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Pseudomonas aeruginosa
Staphyllococcus aureus
Clostridium difficile
Clostridium botulinum
Bordetella pertussis
Vibrio cholerae
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