Liver Pathology MCQs Quiz With Answers

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Liver Pathology MCQs Quiz With Answers - Quiz

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The liver is an essential organ that performs many major bodily functions. It's a crucial metabolic organ. Our liver pathology MCQs quiz with answers will test your knowledge of hepatic functioning. The liver is a delicate organ with intricate hormonal pathways that are crucial for basic functioning. Do you have a good grasp of your concepts? Our quiz questions are presented in a simple, easy-to-understand MCQ format. You will be given four choices and have to pick the correct answer. Make sure to read all the questions carefully. Keep learning and have fun!


Questions and Answers
  • 1. 

    Which liver disease classification is characterized by liver malfunction due to a blockage in bile ducts and is treated surgically.?

    • A.

      Obstructive

    • B.

      Diffuse

    • C.

      Hepatocellular

    • D.

      None of the above

    Correct Answer
    A. Obstructive
    Explanation
    Obstructive liver disease is characterized by liver malfunction caused by a blockage in the bile ducts. This blockage prevents the normal flow of bile, leading to a buildup of bile in the liver. Surgical intervention is often required to remove the blockage and restore proper bile flow. Diffuse liver disease refers to conditions that affect the entire liver, while hepatocellular liver disease involves damage to the liver cells themselves. None of these classifications specifically involve a blockage in the bile ducts, making obstructive the correct answer.

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  • 2. 

    Which obstruction level will lead to only intrahepatic ducts dilating?

    • A.

      A

    • B.

      B

    • C.

      C

    Correct Answer
    A. A
    Explanation
    Obstruction level A will lead to only intrahepatic ducts dilating.

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  • 3. 

    What level of obstruction would a lesion distal to cystic duct and head of pancreas be classified as?

    • A.

      A

    • B.

      B

    • C.

      C

    • D.

      None of the above

    Correct Answer
    C. C
    Explanation
    A lesion distal to the cystic duct and head of the pancreas would be classified as none of the above. This means that it does not fall into any of the given categories A, B, or C. The question does not provide any specific classification for this type of lesion, suggesting that it may have unique characteristics or require a different classification system altogether.

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  • 4. 

    What does pruritus mean?

    • A.

      Nausea

    • B.

      Malaise

    • C.

      Itching

    • D.

      Numbness

    Correct Answer
    C. Itching
    Explanation
    Pruritus refers to itching, which is a sensation that causes the desire to scratch. It is a common symptom of various skin conditions, allergies, and certain systemic diseases. Nausea is a feeling of sickness in the stomach, malaise is a general feeling of discomfort or unease, and numbness refers to a loss of sensation. Therefore, the correct answer is itching.

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  • 5. 

    Stones in common bile duct and stricture of the common bile duct may cause

    • A.

      Proximal biliary duct obstruction

    • B.

      Distal biliary duct obstruction

    • C.

      Both

    • D.

      None of the above

    Correct Answer
    B. Distal biliary duct obstruction
    Explanation
    Stones in the common bile duct can cause a blockage in the distal part of the biliary duct, leading to distal biliary duct obstruction. Similarly, a stricture (narrowing) of the common bile duct can also result in a blockage in the distal part of the duct. Therefore, both stones in the common bile duct and a stricture of the duct can cause distal biliary duct obstruction.

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  • 6. 

    An obstruction proximal to cystic duct can be caused by

    • A.

      Metastatic tumor invasion of porta hepatis

    • B.

      Lymph nodes

    • C.

      CBD stones

    • D.

      Pancreatic head mass

    • E.

      A and b

    • F.

      A and d

    Correct Answer
    E. A and b
    Explanation
    An obstruction proximal to the cystic duct can be caused by metastatic tumor invasion of porta hepatis and lymph nodes. This means that if there is a tumor that has spread to the porta hepatis or the lymph nodes in the area, it can block the flow of bile through the cystic duct. This can lead to symptoms such as jaundice and abdominal pain. CBD stones and a pancreatic head mass can also cause obstructions, but they are not included in the given answer.

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  • 7. 

    Patient with congestive heart failure presents with hepatomegaly and slilghtly elevated lab values. Ultrasound findings: dilation of IVC, SMV, HV, PV and splenic veins. What is your diagnosis?

    • A.

      Cirrhosis

    • B.

      Glycogen storage disease

    • C.

      Hepatatis

    • D.

      Passive hepatic congestion

    Correct Answer
    D. Passive hepatic congestion
    Explanation
    The given ultrasound findings of dilation of the IVC, SMV, HV, PV, and splenic veins suggest a diagnosis of passive hepatic congestion. Passive hepatic congestion occurs when there is impaired blood flow out of the liver, leading to an accumulation of blood within the hepatic veins and subsequent hepatomegaly. This can be seen in conditions such as congestive heart failure, where the heart's pumping ability is compromised, causing blood to back up into the liver. The slightly elevated lab values further support this diagnosis.

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  • 8. 

    Common Duct Stricture is common in patients with

    • A.

      Hepatatis B

    • B.

      Fatty liver

    • C.

      Post cholecystectomy

    • D.

      Pancreatic head mass

    Correct Answer
    C. Post cholecystectomy
    Explanation
    Common duct stricture refers to the narrowing or obstruction of the common bile duct, which carries bile from the liver and gallbladder to the small intestine. Post-cholecystectomy refers to the period after the surgical removal of the gallbladder. It is a common complication of cholecystectomy, and it can lead to the development of common duct stricture. Therefore, post-cholecystectomy is a likely cause of common duct stricture.

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  • 9. 

    Hepatatis B

    • A.

      Due to fecal contamination

    • B.

      Half of cases develop into chronic hepatitis

    • C.

      Due to blood transfusions or sexual contact

    • D.

      Lasts

    Correct Answer
    C. Due to blood transfusions or sexual contact
    Explanation
    Hepatitis B is a viral infection that can be transmitted through blood transfusions or sexual contact. It is not primarily caused by fecal contamination. Approximately half of the cases of Hepatitis B progress to chronic hepatitis, which means the infection persists for a long period of time. The duration of the infection can vary from person to person.

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  • 10. 

    Hepatatis B is predisposed by Hepatatis D

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    Hepatatis D is predisposed by B

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  • 11. 

    Acute hepatatis

    • A.

      Decrease in liver echogenicity

    • B.

      Increase in liver chogenicity

    • C.

      No increase in liver size

    • D.

      Can lead to cirrhosis and liver failure

    • E.

      All of the above

    Correct Answer
    A. Decrease in liver echogenicity
    Explanation
    Acute hepatitis refers to inflammation of the liver. One of the characteristic features of acute hepatitis is a decrease in liver echogenicity, which means that the liver appears less bright on imaging studies such as ultrasound. This decrease in echogenicity is due to the infiltration of inflammatory cells and edema in the liver tissue. The other options mentioned, such as an increase in liver chogenicity, no increase in liver size, and the potential complications of cirrhosis and liver failure, are not specifically associated with acute hepatitis.

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  • 12. 

    Chronic hepatatis

    • A.

      Fatty changes and fibrosis

    • B.

      Coarse hepatic texture

    • C.

      Hepatomegaly

    • D.

      Gallbladder wall thickening

    • E.

      A and b

    • F.

      All of the above

    Correct Answer
    E. A and b
    Explanation
    The given answer, "a and b," is correct because chronic hepatitis can lead to both fatty changes and fibrosis in the liver. Fatty changes refer to the accumulation of fat within liver cells, while fibrosis is the formation of scar tissue in the liver. Both of these conditions can contribute to a coarse hepatic texture and hepatomegaly (enlarged liver). Additionally, chronic hepatitis can also cause gallbladder wall thickening. Therefore, all of the mentioned symptoms are associated with chronic hepatitis.

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  • 13. 

    Check the lab values associated with hepatatis

    • A.

      Increase in AST

    • B.

      Bilirubin decrease

    • C.

      Increase in ALT, then falls rapidly after several days

    • D.

      Lekopenia

    • E.

      Bilirubin increase

    • F.

      Decrease in AST

    Correct Answer(s)
    A. Increase in AST
    C. Increase in ALT, then falls rapidly after several days
    D. Lekopenia
    E. Bilirubin increase
    Explanation
    The correct answer is a combination of lab values associated with hepatitis. In hepatitis, there is typically an increase in AST and ALT, which are liver enzymes. The levels of these enzymes may initially rise and then fall rapidly after several days. Additionally, hepatitis can cause leukopenia, which is a decrease in white blood cell count. Finally, there is an increase in bilirubin, which is a yellow pigment produced by the liver and is elevated in liver diseases.

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  • 14. 

    Which symptom is not associated with an extrahepatic lesion?

    • A.

      Discontinuity of liver capsule

    • B.

      External bulging of the liver capsule

    • C.

      Anterior displacement of right kidney

    • D.

      Anteriormedial shift of IVC

    • E.

      Internal invagination of the liver capsule

    Correct Answer
    B. External bulging of the liver capsule
    Explanation
    An extrahepatic lesion refers to a condition or abnormality that occurs outside of the liver. The symptoms associated with an extrahepatic lesion include discontinuity of the liver capsule, anterior displacement of the right kidney, anteriormedial shift of the IVC, and internal invagination of the liver capsule. However, external bulging of the liver capsule is not typically associated with an extrahepatic lesion. This means that the correct answer is "external bulging of the liver capsule."

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  • 15. 

    Which is not a sign of an intrahepatic mass?

    • A.

      Formation of a triangular fat wedge

    • B.

      Displacement of hepatci vascular

    • C.

      External bulging ofthe liver capsule

    • D.

      Posterior displacement of the IVC

    Correct Answer
    A. Formation of a triangular fat wedge
    Explanation
    The formation of a triangular fat wedge is not a sign of an intrahepatic mass. Intrahepatic masses typically present with displacement of hepatic vasculature, external bulging of the liver capsule, and posterior displacement of the IVC. However, the formation of a triangular fat wedge is not typically associated with an intrahepatic mass.

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  • 16. 

    A patient with a fever, vomiting, and RUQ pain presents to the ER. LFT are elevated and the patient has increased WBC. Sonographic exam reveals a 2 cm round, echogenic lesion in the right lobe.

    • A.

      Focal nodular hyperplasia

    • B.

      Pyogenic abscess

    • C.

      Cholangiocarcinoma

    • D.

      Bacterial hepatatis

    Correct Answer
    B. Pyogenic abscess
    Explanation
    The given clinical presentation of fever, vomiting, RUQ pain, elevated LFTs, increased WBC count, and a 2 cm round, echogenic lesion in the right lobe on sonographic exam is consistent with a pyogenic abscess. Pyogenic abscesses are commonly caused by bacterial infections and can result in localized inflammation and collection of pus in the liver. The symptoms and imaging findings described align with this diagnosis. Focal nodular hyperplasia is a benign liver lesion that typically does not present with fever or other symptoms. Cholangiocarcinoma is a malignant tumor of the bile ducts and would not typically present with acute symptoms. Bacterial hepatitis may present with similar symptoms, but the presence of a distinct lesion on imaging suggests a localized abscess rather than diffuse liver inflammation.

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  • 17. 

    Candidiasis Infection usually affecs

    • A.

      Patients with metastatic liver lesions

    • B.

      Hepatatis B patients

    • C.

      Patients with cirrhosis

    • D.

      Immunocompromised patients

    Correct Answer
    D. Immunocompromised patients
    Explanation
    Immunocompromised patients are more susceptible to Candidiasis infection. This is because their weakened immune system cannot effectively fight off the Candida fungus, which is responsible for causing the infection. Immunocompromised individuals include those with HIV/AIDS, undergoing chemotherapy, organ transplant recipients, and individuals with certain autoimmune diseases. These patients have a reduced ability to mount an immune response, making them more vulnerable to infections like Candidiasis.

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  • 18. 

    Pain, diarrhea and black tarry stool are GI symptoms of

    • A.

      Amoebic abscess

    • B.

      Pyogenic abscess

    • C.

      Acute hepatatis

    • D.

      Echinococcal cyst

    Correct Answer
    A. Amoebic abscess
    Explanation
    The correct answer is amoebic abscess. Pain, diarrhea, and black tarry stool are common gastrointestinal symptoms associated with amoebic abscess. Amoebic abscess is caused by the parasite Entamoeba histolytica, which can infect the liver and form abscesses. The infection can lead to abdominal pain, diarrhea, and the passage of black tarry stool due to bleeding in the gastrointestinal tract. Pyogenic abscess, acute hepatitis, and echinococcal cyst may also cause gastrointestinal symptoms, but they are not specifically associated with black tarry stool.

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  • 19. 

    Schistosomiasis is transmitted through ingested water

    • A.

      True

    • B.

      False

    Correct Answer
    B. False
    Explanation
    not transmitted through ingested water. amebic abscess is transmitted through ingested water.

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  • 20. 

    Autosomal recessive genetic disorder of carbohydrate metabolism. Most common type is Von Gierke's disease.

    • A.

      Glycogen storage disease

    • B.

      Hemochromatosis

    • C.

      Hemagioma

    • D.

      Cirrhosis

    Correct Answer
    A. Glycogen storage disease
    Explanation
    Glycogen storage disease is the correct answer because it is an autosomal recessive genetic disorder that affects carbohydrate metabolism. The most common type of this disease is Von Gierke's disease. In this condition, the body is unable to break down glycogen properly, leading to a buildup of glycogen in the liver and muscles. This can result in symptoms such as low blood sugar, enlarged liver, and growth delays. Therefore, glycogen storage disease is the most appropriate answer based on the given information.

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Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Aug 19, 2023
    Quiz Edited by
    ProProfs Editorial Team
  • Nov 02, 2010
    Quiz Created by
    Dearmelina
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