Diffuse Liver Pathology- Cirrhosis

25 Questions | Total Attempts: 285

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Liver Pathology Quizzes & Trivia

Questions and Answers
  • 1. 
    Cirrhosis is a chronic degenerative disease in which normal liver cells are damaged and are then replaced by ___________ _______________ or ____________ and regenerative ________________.
  • 2. 
    The fibrosis and nodule formation causes ______________ of the normal liver architecture which interferes with ______________ _______________ through the liver, leading to progressive loss of liver function.
  • 3. 
    Cirrhosis is created by three pathologic mechanism including __________ _____________, ____________ and _____________.
  • 4. 
    The disease that leads to cirrhosis ____________ and ___________ liver cells, then try to repair themselves causing __________ ___________ to form, which is ______________.
  • 5. 
    The liver cells that do not die ____________ in an attempt to replace the cells that have died. This results in clusters of newly formed liver cells, or ________________ ________________, with the scar tissue.
  • 6. 
    Cirrhosis is the ____th leading cause of death in the US
  • 7. 
    The primary cause of cirrhosis in the US is long term ______________.
  • 8. 
    Chronic liver infections, such as hepatitis b and particularly hepatitis c, are commonly linked to ____________.
  • 9. 
    Cirrhosis may also be caused by...
    • A. 

      Chronic biliary obstruction

    • B. 

      Liver injury

    • C. 

      Reactions to prescription meds

    • D. 

      Exposure to toxic substances

    • E. 

      Repeated episodes of heart failure with liver congestion

  • 10. 
    Symptoms and lab values depend of the _________ and ____________ of the disease.
  • 11. 
    In early stages, patients may present with...
    • A. 

      Dull abdominal pain (due to hepatomegaly)

    • B. 

      Fatigue

    • C. 

      Weight loss

    • D. 

      Diarrhea

    • E. 

      Red palms

  • 12. 
    As the disease progresses and complications develop, patients may also present with...
    • A. 

      Jaundice

    • B. 

      Spider angiomata

    • C. 

      Ascites

    • D. 

      Splenomegaly

    • E. 

      Itching

  • 13. 
    The itching associated with cirrhosis is due to ______________.
  • 14. 
    Splenomegaly associated with cirrhosis is due to blood back up through where?
  • 15. 
    Clinically, the lab values that will be elevated are
    • A. 

      AST and ALT with AST

    • B. 

      AST and ALT with AST>ALT

    • C. 

      ALP

    • D. 

      Bilirubin

    • E. 

      Prothrombin time

    • F. 

      Decreased albumin

    • G. 

      Increased albumin

  • 16. 
    One complication of cirrhosis is portal ______________.
  • 17. 
    Portal hypertension causes __________________ of the umbilical vein ( __________________ _________________)
  • 18. 
    Another complication of cirrhosis is esophageal varices, collateral flow from _______________ portal venous pressure, which may cause ______________ bleeding.
  • 19. 
    Another complication of cirrhosis is ascites, caused by the decreased levels of _____________.
  • 20. 
    Portal hypertension is characterized by:
    • A. 

      Recannalized ligamentum teres

    • B. 

      Hepatopedal flow

    • C. 

      Hepatofugal flow

    • D. 

      Splenomegaly

  • 21. 
    Sonographically, cirrhosis _______________ in appearance during disease progression.
  • 22. 
    Sono appearance-Early features include ___________________ and __________________ echogenicity of the liver parenchyma.
  • 23. 
    Sono appearance-In early stages, it is difficult to differentiate between other ______________ disease processes.
  • 24. 
    Sono appearance of late stage cirrhosis may include:
    • A. 

      Atrophic liver, especially the right lobe

    • B. 

      Atrophic liver, especially the caudate lobe

    • C. 

      Caudate lobe hypertrophy

    • D. 

      Surface nodularity seen when ascites is present

    • E. 

      Coarse echotexture

    • F. 

      Findings related to PHTN

    • G. 

      Splenomegaly

    • H. 

      Ascites

    • I. 

      Hepatoma

    • J. 

      Increased echogenicity

    • K. 

      Decreased echogenicity

  • 25. 
    Sono appearance-The liver is heterogenous due to ______________ and ________________ _________________.
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