Cytoskeleton And Muscle Biochemistry

18 Questions | Total Attempts: 99

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Skeleton Quizzes & Trivia

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Questions and Answers
  • 1. 
    Which is a microfilament?
    • A. 

      Actin

    • B. 

      Vimentin

    • C. 

      Keratin

    • D. 

      Desmin

  • 2. 
    Which is NOT a molecular motor ?
    • A. 

      Dynein

    • B. 

      Actin

    • C. 

      Myosin

    • D. 

      Dynamin

  • 3. 
    Which component of cytoskeleton is defective in kartageners syndrome ?
    • A. 

      Dynein

    • B. 

      Actin

    • C. 

      Myosin

    • D. 

      Dynamin

  • 4. 
    Which component of cytoskeleton is defective in epidermolysis bullosa ?
    • A. 

      Desmin

    • B. 

      Vimentin

    • C. 

      Keratin

    • D. 

      Dynamin

  • 5. 
    Hutchinson-Gilford progeria syndrome is due to mutation of 
    • A. 

      Keratin A

    • B. 

      Keratin B

    • C. 

      Lamin A

    • D. 

      Lamin B

  • 6. 
    Griseofulvin is a tubulin inhibitor
    • A. 

      True

    • B. 

      False

  • 7. 
    Microfilaments are dynamic structures which undergo rapid assembly and disassembly.
    • A. 

      True

    • B. 

      False

  • 8. 
    TRUE about positive end of actin filament
    • A. 

      Addition and dissociation of actin monomers are slow at +Ve end

    • B. 

      ATP binding promotes the addition of actin monomers

    • C. 

      ADP binding promotes the addition of actin monomers

    • D. 

      None

  • 9. 
    Calcium binding motif present in calmodulin is known as
    • A. 

      Rossman fold

    • B. 

      EF hand

    • C. 

      Zinc finger

    • D. 

      Actin fold

  • 10. 
    Calcium binding results in a conformational change in troponin complex that pulls tropomyosin from the actin binding sites of myosin.
    • A. 

      True

    • B. 

      False

  • 11. 
    Sarcomere is a segment between 
    • A. 

      H and I bands

    • B. 

      Two I bands

    • C. 

      Two Z disk

    • D. 

      None

  • 12. 
    Myosin binding sites on actin are blocked by Troponin
    • A. 

      True

    • B. 

      False

  • 13. 
    TRUE about A band
    • A. 

      Consists only of thin filaments

    • B. 

      Contains the entire length of a single thick filament

    • C. 

      I band is a component of A band

    • D. 

      None

  • 14. 
    Kinesin is involved in retrograde trasport. Dynein is involved in anterograde transport.
    • A. 

      True

    • B. 

      False

  • 15. 
    Flagella is not found in humans.
    • A. 

      True

    • B. 

      False

  • 16. 
    Length of actin and myosin doesn't change during muscle contraction
    • A. 

      True

    • B. 

      False

  • 17. 
    Troponin C binds to 
    • A. 

      2 calcium

    • B. 

      3 calcium

    • C. 

      4 calcium

    • D. 

      5 calcium

  • 18. 
    Malignant hyperthermia is due to mutation of 
    • A. 

      RYR1

    • B. 

      ATPase 7A

    • C. 

      ATPase 7B

    • D. 

      None