Chapter 4 Physiological Psychology Mid-term Study Quiz
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Psychopharmacology
- 1.Carrots, when eaten in high enough quantities, will turn your skin orange (it's true!). However, they're not considered drugs, why not?
- A.
They're not exogenous.
- B.
The effect requires too high a dosage.
- C.
The effect doesn't actually change how the bodily cells function, only how they appear
- D.
They are a drug, most people just don't view them like that
- 2.___________ is the study of what the body does to a drug.
- A.
Pharmacokinetics
- B.
Pharmacodynamics
- C.
Psychopharmacology
- D.
Psychopharmodynamics
- 3.Which of the following is the slowest drug absorption?
- A.
Intravenous
- B.
Intramuscular
- C.
Oral administration
- D.
Inhalation
- 4.A low therapeutic index is an indicator that ____________.
- A.
Care must be given to prescribing because the margin of safety is small.
- B.
The drug is incredibly safe because the median lethal dose is relatively low
- C.
The drug is incredibly safe because the median lethal dose is relatively high
- D.
The drug is not very effective
- 5.____________ is a phenomena where drugs bind with proteins in the blood.
- A.
Inactivation
- B.
Depot binding
- C.
Covalent binding
- D.
Ionic binding
- 6.A drug with high affinity generally requires ________.
- A.
A higher dose
- B.
A lower dose
- C.
A same size dose as it would with a low affinity
- D.
The drug to be administered intravenously
- 7.____________ is the study of what a drug does to the body.
- A.
Pharmacokinetics
- B.
Pharmacodynamics
- C.
Therapeutic Index
- D.
Drug distribution
- 8.Enzymes in the __________ deactivate drugs in the body.
- A.
Kidney
- B.
Liver
- C.
Stomach
- D.
Pancreas
- 9.
- A.
You can attach chemicals in a more dense form onto a lipid-soluble drug than a water-soluble drug
- B.
The immune system would recognize water-soluble drugs as invaders and fight them
- C.
The blood brain barrier is only a barrier for water-soluble molecules so lipid soluble drugs pass through
- D.
Water-soluble drugs would alter the pH value of the bloodstream and therefore have significant side effects compared to lipid-soluble drugs.
- 10.____________ is an example of drug tolerance.
- A.
Having to down 6 Smirnoff Twists to get buzzed when 2 used to be enough
- B.
Feeling the opposite of drunk and strongly desiring more alcohol
- C.
Feeling really sick after just one shot of tequila (and it just so happens you got really drunk and threw up after having tequila last week-end)
- D.
Feeling drunk even though your friend slipped you O'Doul's (non-alcoholic beer) as a prank
- 11.__________ is an example of drug withdrawal.
- A.
Having to down 6 Smirnoff Twists to get buzzed when 2 used to be enough
- B.
Feeling the opposite of drunk and strongly desiring more alcohol
- C.
Feeling really sick after just one shot of tequila (and it just so happens you got really drunk and threw up after having tequila last week-end)
- D.
Feeling drunk even though your friend slipped you O'Doul's (non-alcoholic beer) as a prank
- 12.__________ is an example of drug sensitization.
- A.
Having to down 6 Smirnoff Twists to get buzzed when 2 used to be enough
- B.
Feeling the opposite of drunk and strongly desiring more alcohol
- C.
Feeling really sick after just one shot of tequila (and it just so happens you got really drunk and threw up after having tequila last week-end)
- D.
Feeling drunk even though your friend slipped you O'Doul's (non-alcoholic beer) as a prank
- 13.___________ is an example of placebo effect.
- A.
Having to down 6 Smirnoff Twists to get buzzed when 2 used to be enough
- B.
Feeling the opposite of drunk and strongly desiring more alcohol
- C.
Feeling really sick after just one shot of tequila (and it just so happens you got really drunk and threw up after having tequila last week-end)
- D.
Feeling drunk even though your friend slipped you O'Doul's (non-alcoholic beer) as a prank
- 14.A drug that attaches itself to a postsynaptic binding site and opens the corresponding ion channel is an example of a ________________.
- A.
Direct agonist
- B.
Direct antagonist
- C.
Indirect antagonist
- D.
Receptor blocker
- 15.A drug that attaches itself to a postsynaptic binding site but does not open the corresponding ion channel is an example of a ________________.
- A.
Direct agonist
- B.
Direct antagonist
- C.
Indirect antagonist
- D.
Drug mimic
- 16.A drug that engages in noncompetitive binding, thereby preventing the ion channel from opening, is an example of a _____________
- A.
Direct agonist
- B.
Direct antagonist
- C.
Indirect antagonist
- D.
Drug mimic
- 17.A hetereoreceptor is said to have _____________.
- A.
The ability to depot bind
- B.
The ability to activate enzymatic deactivation
- C.
Low specificity
- D.
High specificity
- 18.Autoreceptors are different from normal postsynaptic receptors because _______________.
- A.
They do not require neurotransmitters to activate; they activate automatically.
- B.
They are activated by neurotransmitters within the cell
- C.
They react to hormones, not neurotransmitters
- D.
They activate AChE to destroy ACh
- 19.Drug tolerance is an example of _____________.
- A.
The body down-regulating
- B.
The body up-regulating
- C.
The body attaining lower specificity
- D.
The body attaining higher affinity
- 20.The primary excitatory neurotransmitter in the brain is ____________.
- A.
GABA
- B.
Seretonin
- C.
Acetylcholine
- D.
Glutamate
- 21.The primary inhibitory neurotransmitter in the brain is ___________.
- A.
GABA
- B.
Seretonin
- C.
Acetylcholine
- D.
Glutamate
- 22.__________ can alter the action of systems of neurons that transmit information using glutamate or GABA.
- A.
M-system
- B.
Norepineprhine
- C.
A neuromodulator
- D.
D-system
- 23.The primary neurotransmitter secreted by efferent CNS cells is _____________.
- A.
GABA
- B.
Seretonin
- C.
Acetylcholine
- D.
Glutamate
- 24.When released in the brain, Acetylcholine usually results in ___________.
- A.
Facilitory effects
- B.
Inhibitory effects
- C.
Activation of autoreceptors
- D.
Activation of heteroreceptors
- 25.AChE's primary function in the body is to ______________.
- A.
Synthesize more ACh
- B.
Serve as a binding receptor to ACh
- C.
Destroy ACh during enzymatic deacitvation
- D.
Serve as a catecholamine
- 26.Nicotinic receptors are _______________ for ACh, and muscarinic receptors are ___________ for ACh.
- A.
Metabotropic antagonist; metabotropic agonists
- B.
Metabotropic agonist; ionotropic agonists
- C.
Ionotropic antagonist; metabotropic antagonist
- D.
Ionotropic agonists; metabotropic agonist
- 27.Which of the following is a monamine but not a catecholamine?
- A.
Dopamine
- B.
Seretonin
- C.
Epinephrine
- D.
Norepinephrine
- 28.Which of the following correctly describes the synthesis of norepinephrine?
- A.
Tyrosine -> 5HTP -> Serotonin -> Norepinephrine
- B.
Tryptophan -> 5HTP -> Epinephrine -> Norepinephrine
- C.
Tryptophan -> L-DOPA -> Dopamine -> Norepinephrine
- D.
Tyrosine -> L-DOPA -> Dopamine -> Norepinephrine
- 29._________ is involved in movement, attention, learning, and addiction.
- A.
Dopamine
- B.
Seretonin
- C.
Epinephrine
- D.
Norepinephrine
- 30._________ is involved in the sympathetic division of the autonomic nervous system.
- A.
Dopamine
- B.
Seretonin
- C.
Epinephrine
- D.
Norepinephrine
- 31.Which of the following correctly describes the synthesis of serotonin?
- A.
Tryptophan -> L-DOPA -> Serotonin
- B.
Tryptophan -> 5HTP -> Serotonin
- C.
Tyrosine -> 5HTP -> Serotonin
- D.
Tyrosine -> L-DOPA -> Serotonin
- 32.98% of the serotonin in the body can be found in _____________.
- A.
The brain
- B.
The heart
- C.
The bloodstream
- D.
The gut
- 33.___________, originating in the _________ does forms synapses.
- A.
D System; dorsal raphe nucleus
- B.
V System; ventral raphe nucleus
- C.
M System; median raphe nucleus
- D.
C System; caudal raphe nucleus
- 34.Prozac is an example of a drug that serves a reuptake inhibitor of ____________. It is used to treat depression, some types of anxiety disorders, and obsessive-compulsive disorder.
- A.
Dopamine
- B.
Seretonin
- C.
Epinephrine
- D.
Norepinephrine
- 35.Which of these is not true about GABA?
- A.
It is the principal inhibitory neurotransmitter in the brain
- B.
Tetanus toxin is a GABA antagonist by inhibiting its release
- C.
Parkinson's Disease involves degeneration of GABA cells in basal ganglia
- D.
Strychnine is a GABA antagonist by blocking its receptors
- 36.____________ is an inhibitory neurotransmitter in the spinal cord and lower portions of the brain.
- A.
GABA
- B.
Glycine
- C.
Glutamate
- D.
Choline
- 37.Similar to ____________, tetanus toxin and strychnine serve as antagonists toward glycine.
- A.
Dopamine
- B.
GABA
- C.
Glutamate
- D.
Choline
- 38.After a cell releases peptides, what occurs?
- A.
Reuptake cycle
- B.
Enzymatic deactivation
- C.
AChE destroys the peptides
- D.
Nothing
- 39.Which of the following is not a common side effect of THC (despite the best efforts of an old nun to persuade me she commonly experiences it, funny story, ask me sometime)?
- A.
Analgesia
- B.
Sedation
- C.
Distorted perception of the passage of time
- D.
Vivid visual hallucinations
- 40.What is anandamide and where is it stored?
- A.
Natural analgesic; liver
- B.
Peptide neurotransmitter; synaptic vesicles
- C.
Natural ligand for THC receptor; not stored at all
- D.
Predecessor to formation of epinephrine; formed from enzymatic deactivation of norepinephrine
- 41.Which of the following is not a drug that causes sedation?
- A.
Barbiturates
- B.
Dopamine receptor blockers
- C.
Ethyl Alcohol
- D.
Benzodiazepines
- 42.Which of the following is not a drug that causes excitation?
- A.
Nicotine
- B.
Amphetamine
- C.
Methylenedioxymethamphetamine (MDMA)
- D.
Cocaine
- 43.Which of the following is not a drug that modifies perception or produces hallucinations?
- A.
PCP
- B.
THC
- C.
Mescaline
- D.
Opiates
- 44.Which of the following is not a psychotherapeutic drug?
- A.
Adenosine agonist
- B.
Inhibitors of serotonin or norepinephrine re-uptake
- C.
Lithium carbonate
- D.
Monoamine oxidase inhibitors
- 45.Which of the following is not an analgesic drug?
- A.
Opiates
- B.
Antidepressant drugs
- C.
Aspirin
- D.
Opium
- 46.Barbiturates facilitate ________ binding, and are therefore said to _______ it's affinity.
- A.
GABA; decrease
- B.
GABA; increase
- C.
Glutamate; decrease
- D.
Glutamate; increase
- 47.Valium, a benzodiazepine, has the behavior effect of ___________.
- A.
Reducing anxiety but suppressing dreaming (bad sleep medication)
- B.
Reducing anxiety and facilitating sleep
- C.
Making the individual happier but suppressing dreaming (bad sleep medication)
- D.
Making the individual happier and facilitating sleep
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