Quiz 2 Practical Kinetics II ( Lab 5 & 7)

5 Questions | Total Attempts: 82

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Quiz 2 Practical Kinetics II ( Lab 5 & 7)

Group of MUST Pharmacy Pharmacokinetics Practical Quiz 2


Questions and Answers
  • 1. 
    A women 50 kg given IV two compartment 2 mg/kg and conc. of elemination is 5 mg/l the conc. of distribution when volume of central compartment equal 10 mg/l is
    • A. 

      3 mg/l

    • B. 

      5 mg/l

    • C. 

      0 mg/l

    • D. 

      20 mg/l

  • 2. 
    • A. 

      1.2/hr

    • B. 

      0.9/hr

    • C. 

      1.046/hr

    • D. 

      0.9/min

  • 3. 
    A  Single IV dose of new Antibiotic was given to 50 kg women at dose level 20 mg/kg. Urine and Blood samples were removed periodically and examined for parent drug found elemination rate constant equal 0.679 hr-1 at 10 hours the rate of drug accumulation in the urine when total amount of drug excreted in urine is 0.9 g
    • A. 

      0.687 mg/l

    • B. 

      6.87 mg/l

    • C. 

      0.687 mg/hr

    • D. 

      6.87 X 10-4 mg/hr

  • 4. 
    A drug follows two compartment open model was given IV and the following data are obtained the dose was given 1 gm Calculate the rate of elemination constant(Kel) :
    • A. 

      0,25 hr-1

    • B. 

      0.24 hr-1

    • C. 

      0.52 hr-1

    • D. 

      0.14 hr-1

  • 5. 
    A drug follows two compartment open model was given IV at plasma drug  concentration 15 mg/l and after 3 hrs if found plasma concentration 10 mg/l when conc. of distribution equal 2.5 mg/l and β equal 0.109 hr-1 ,so slope of distribution equal
    • A. 

      0.43 hr-1

    • B. 

      0.31 hr-1

    • C. 

      0.12 hr-1

    • D. 

      0.25 hr-1