T-cells are is a type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity. A molecule that is capable of binding to an antibody or to an antigen receptor on a T-cell is defined as an antigen. What do you know about how an antigen gets recognized by a T-lymphocyte? Take up the quiz to find out.
True
False
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True
False
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Of a pathogen-derived peptide assembling in a MHC molecule complex so that it can be displayed on the cell surface
Of pathogen derived peptides being degraded
Of removing cells that are self-reactive
Of allowing cells to proliferate
None of the above
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HLA A
HLA B
HLA C
HLA D
A, B and C
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8-10 amino acids
23-90 amino acids
1 amino acid
Highly specific
None of the above
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Alpha domains
Beta domains
Zeta domains
No domains
Both a and b
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True
False
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Made of only DNA
Created when a B-chain is nonproductive
The combination of peptide and MHC molecule on a cell surface
Carried throughout the blood by a protein carrier
Needed to bind to a B-cell
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Valpha domain
Vbeta domain
Vlamda domain
Both a and b
Vdelta domain
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Nonproductive
Self-reactive
Membrane bound
Released into the cytoplasm
Immature
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Nonproductive alpha chain
CDR loop that is mutated
Single binding site for antigen
Noncoding region
Immature chain
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True
False
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Virus infection
Bacteria infection
Sprained ankle
Inflammation
Cancer
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True
False
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True
False
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Help other cells to respond to extracellular sources of infection
Kill viral infected cells
Degrade peptides of pathogens
Select cells for apoptosis
Both b and c
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True
False
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Heart
Bone marrow
Thyroid
Lymph node
Thymus
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Cross deletion
Double presentation
Cross presentation
Substitution
Hypermutation
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The nuceloid region
The major histocompatibility complex
The germinal center
The terminal center
The RNA region
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True
False
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Antibody processing
Antigen processing
Antigen editing
Antigen deletion
Antigen proliferation
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Help other cells respond to extracellular sources of infection
Degrade peptides from pathogens
Deliver pathogens to primary lymph nodes
Kill viral infected cells
Kill bacterial infected cells
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Proteosomes
Immunosupressors
DNA recombinase
TAP
RAG 1
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True
False
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The involution of the thymus
B-cell variation
T-cell overload
Tissue incompatibility and transplant rejection
Organ acceptance
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True
False
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HLA-DO
HLA-DM
HLA-M
HLA-P
HLA-J
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Dendritic
Macrophages
B cells
T cells
All of the above
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True
False
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HLA C
HLA E
HLA B
HLA G
Both E and G
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True
False
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Gene families
Genetic polymorphism
Both a and b
None of the above
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True
False
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T-cell receptor
B-cell receptor
MHC receptor
MHC II receptor
Both a and b
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Increasing the potential of combinations of gene segments
Extra N nucleotides added at the junction between the two D segments
Both a and b
Deleting variable segments
Adding J gene segments
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True
False
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Chromosome 14
Chromosome 21
Chromosome 13
Chromosome 87
None of the above
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Gene rearrangements that generate V-region sequence
Changes in mRNA splicing
Both a and b
Changes in tRNA splicing
None of the above
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They are deleted
They are done fighting infection
They die
They dont have an invarient chain
They leave the ER
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1
2
4
8
22
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Genes are turned on by MHC class II transactivator
CIITA is induced by IFN-y
LMP2 and LMP7 replace proteasome subunits
All of the above
None of the above
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Peptide-binding motif
MHC restriction
Anchor residues
Balancing selection
None of the above
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True
False
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8-10 amino acids
4-9 amino acids
13-25 amino acids
90-999 amino acids
35-67 amino acids
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Aid in the loading of peptides in MHC class I molecules
Aid in the deletion of peptides in MHC class II molecules
Are not involved in MHC class I and II molecules
Deliver a chain of events benefiting apoptosis
Remove exons
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CD8 T cells about the presence of extracellular infection
CD4 T cells about the presence of intracellular infection
CD8 T cells about the presence of intracellular infection
CD4 T cells about the presence of extracellular infection
None of the above
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Chromosome 6
Chromosome 89
Chromosome 13
Chromosome 23
Chromosome 11
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