Carbohydrate Metabolism Lecture Questions

8 Questions | Total Attempts: 3051

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Carbohydrate Metabolism Lecture Questions

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Questions and Answers
  • 1. 
    The primary source of energy (ATP) under conditions of oxygen limitation in tissues is?
    • A. 

      The Alanine Cycle

    • B. 

      The Kreb’s Cycle (TCA)

    • C. 

      Oxidative Phosphorylation

    • D. 

      Glycolysis

    • E. 

      The Cori Cycle

  • 2. 
    The most important allosteric regulator of glycolysis is fructose 1,6-bisphosphate?
    • A. 

      True

    • B. 

      False

  • 3. 
    Gluconeogenesis is most important?
    • A. 

      After exercise

    • B. 

      After meals

    • C. 

      After prolonged fasting

    • D. 

      Between lunch and dinner.

    • E. 

      With anaerobic conditions

  • 4. 
    An important allosteric regulator of gluconeogenesis is fatty-acyl-CoA?
    • A. 

      True

    • B. 

      False

  • 5. 
    Number of hepatic translocases and/or enzymes which could be responsible for an observed failure of a patient to convert cytosolic glucose-6-phosphate into intracellular free glucose?
    • A. 

      1

    • B. 

      2

    • C. 

      3

    • D. 

      4

    • E. 

      5

  • 6. 
    High free fatty acids are a hallmark of metabolic syndrome, a common precondition of Type II diabetes. High circulating fatty acids chronically cause modified phosphorylation on the intracellular domain of the insulin receptor, with reduced PI3K and reduced GLUT4 activity. How is low GLUT4 activity relevant to diabetes?
    • A. 

      It causes retinopathy

    • B. 

      It prevents glucose utilization by cells

    • C. 

      It stimulates fructose uptake by cells

    • D. 

      It leads to hyper-stimulation of glycolysis

    • E. 

      It leads to a common foot infection

  • 7. 
    Ischemic tissues have an increased rate of glycolysis. Most of this is not fueled by extracellular supply of glucose, but rather by locally stored glycogen that is degraded in response to ischemia. This response depends on the activation of glycogen phosphorylase by:
    • A. 

      ATP

    • B. 

      AMP

    • C. 

      Low pH

    • D. 

      Carbon Dioxide

    • E. 

      Glucose 6-phosphate

  • 8. 
    Several inborn errors of carbohydrate metabolism can cause fasting hypoglycemia. The most severe fasting hypoglycemia has to be expected in deficiencies of:
    • A. 

      Phosphofructokinase

    • B. 

      Aldolase

    • C. 

      Glycogen phosphorylase

    • D. 

      Fructose-1,6-bisphosphatase

    • E. 

      Glucose-6-phosphatase

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