Lipid Metabolism Biochemistry MCQ Quiz With Answers

Reviewed by Farah Naz
Farah Naz, MBBS, Medicine |
Medical Expert
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Farah holds a Bachelor of Medicine and Bachelor of Surgery (MBBS) from Dow University of Health Sciences. She gained valuable experience through internships in Radiology, Cardiology, and Neurosurgery, and has contributed to two research publications in medical journals. Passionate about healthcare education, Farah excels in crafting medical content, including articles, literature reviews, and e-learning courses. Leveraging her expertise, she meticulously reviews medical science quizzes, ensuring accuracy and educational value for aspiring healthcare professionals.
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Lipid Metabolism Biochemistry MCQ Quiz With Answers - Quiz

Do you know about the process of lipid metabolism and how it occurs? Give this lipid metabolism biochemistry MCQ quiz your time and check your knowledge about the same topic. Lipids are energy-rich organic and non-polar molecules. Lipid metabolism involves the synthesis and degradation of lipid cells in our body and is associated with carbohydrate metabolism. What else do you know about the metabolism of lipids? Enhance your learning about lipids with us by taking the quiz given below.


Questions and Answers
  • 1. 

    The acetyl CoA is produced in the mitochondria and must be transported into cytosol for synthesis of fatty acid.  Which of the following is true regarding its transport?

    • A.

      Acetyl CoA is diffused from mitochondrial membrane

    • B.

      Acetyl CoA is transported by its specific transporter protein

    • C.

      Acetyl CoA is converted into pyruvate, enters into cytosol and acetyl CoA is regenerated

    • D.

      Acetyl CoA is converted into citrate, enters into cytosol and acetyl CoA is regenerated.

    Correct Answer
    D. Acetyl CoA is converted into citrate, enters into cytosol and acetyl CoA is regenerated.
    Explanation
    Acetyl CoA cannot directly diffuse from the mitochondrial membrane into the cytosol. Instead, it is converted into citrate within the mitochondria by the enzyme citrate synthase. Citrate is then transported across the mitochondrial membrane into the cytosol, where it is converted back into acetyl CoA by the enzyme ATP-citrate lyase. This allows for the regeneration of acetyl CoA in the cytosol, which is necessary for the synthesis of fatty acids.

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  • 2. 

    Which one of these is not a lipid?

    • A.

      Oils

    • B.

      Fats

    • C.

      Waxes

    • D.

      Proteins

    Correct Answer
    D. Proteins
    Explanation
    Proteins are not lipids. Lipids are a class of biomolecules that include oils, fats, and waxes. They are characterized by their hydrophobic nature and are important for energy storage, insulation, and protection. Proteins, on the other hand, are macromolecules composed of amino acids and have various functions in the body, such as enzyme catalysis, structural support, and transportation. While lipids are primarily composed of carbon, hydrogen, and oxygen, proteins contain carbon, hydrogen, oxygen, nitrogen, and sometimes sulfur. Therefore, proteins do not fit the definition of lipids and are not considered as such.

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  • 3. 

    What are the most active organs in the animal body that can synthesize triacylglycerol?

    • A.

      Liver and intestines 

    • B.

      Kidney and intestines

    • C.

      Gall bladder and kidneys

    • D.

      Pancreas and intestines

    Correct Answer
    A. Liver and intestines 
    Explanation
    The liver and intestines are the most active organs in the animal body that can synthesize triacylglycerol. Triacylglycerol is a type of fat that is synthesized in the liver and intestines through a process called lipogenesis. The liver plays a crucial role in lipid metabolism and is responsible for synthesizing and storing triacylglycerol. The intestines also contribute to the synthesis of triacylglycerol by absorbing dietary fats and converting them into triacylglycerol for storage or energy production. Therefore, the correct answer is liver and intestines.

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  • 4. 

    Fatty acid β-oxidation occurs in

    • A.

      Mitochondria

    • B.

      Peroxisomes

    • C.

      Lysosomes

    • D.

      All of the above

    Correct Answer
    A. Mitochondria
    Explanation
    Fatty acid β-oxidation is a process that occurs in the mitochondria. This is where fatty acids are broken down into acetyl-CoA molecules, which can then enter the citric acid cycle to produce energy. Peroxisomes and lysosomes are involved in other cellular processes, but they do not play a direct role in fatty acid β-oxidation. Therefore, the correct answer is mitochondria.

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  • 5. 

    What is the allosteric regulator of acetyl CoA carboxylase?

    • A.

      Fatty acid

    • B.

      ATP

    • C.

      Citrate

    • D.

      Acetyl CoA

    Correct Answer
    C. Citrate
    Explanation
    Citrate is the correct answer because it acts as an allosteric regulator of acetyl CoA carboxylase. Acetyl CoA carboxylase is an enzyme involved in fatty acid synthesis, and citrate acts as a positive regulator, activating the enzyme. When citrate levels are high, it indicates an abundance of metabolic intermediates, suggesting that the cell has sufficient energy and resources for fatty acid synthesis. Therefore, citrate binding to acetyl CoA carboxylase promotes the production of fatty acids.

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  • 6. 

    Free fatty acids in the plasma 

    • A.

      Circulate in unbound state

    • B.

      Bind to lipoproteins and circulated

    • C.

      Bind to albumin and circulated

    • D.

      Bind to fatty acid binding protein and circulated

    Correct Answer
    C. Bind to albumin and circulated
    Explanation
    Free fatty acids in the plasma bind to albumin and circulate. Albumin is a protein found in the blood that acts as a carrier for various substances, including fatty acids. When fatty acids are released from adipose tissue or dietary intake, they bind to albumin for transport to various tissues in the body. This binding helps to prevent the fatty acids from being rapidly metabolized or excreted, ensuring their delivery to cells where they can be utilized for energy or stored as fat.

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  • 7. 

     Which of the following events inactivates acetyl CoA carboxylase?

    • A.

      ADP-Ribosylation

    • B.

      Glycosylation

    • C.

      Phosphorylation

    • D.

      Farnesylation

    Correct Answer
    C. Phosphorylation
    Explanation
    Phosphorylation is the process of adding a phosphate group to a molecule, which often leads to a change in its activity or function. In the case of acetyl CoA carboxylase, phosphorylation inactivates the enzyme. Acetyl CoA carboxylase is an important enzyme involved in fatty acid synthesis, and its inactivation through phosphorylation helps regulate the production of fatty acids in the cell.

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  • 8. 

    In what compartment does the de novo fatty acid synthesis occur?

    • A.

      Mitochondria

    • B.

      Peroxisome

    • C.

      Endoplasmic reticulum

    • D.

      Cytosol

    Correct Answer
    D. Cytosol
    Explanation
    De novo fatty acid synthesis occurs in the cytosol. This is where the enzymes responsible for the synthesis of fatty acids are located. The process involves the conversion of acetyl-CoA into long-chain fatty acids, which are then used for various cellular functions such as energy storage or membrane synthesis. The cytosol provides a suitable environment for these enzymatic reactions to take place efficiently.

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  • 9. 

    What is the precursor for fatty acid synthesis

    • A.

      Acetyl CoA

    • B.

      Propionyl CoA

    • C.

      Succinyl CoA

    • D.

      Acetoacetyl CoA

    Correct Answer
    A. Acetyl CoA
    Explanation
    Acetyl CoA is the precursor for fatty acid synthesis. Fatty acid synthesis occurs in the cytoplasm of cells and requires Acetyl CoA as the starting molecule. Acetyl CoA is formed from the breakdown of glucose or from the oxidation of fatty acids. It is then converted into malonyl CoA, which is used in the synthesis of fatty acids. Therefore, Acetyl CoA is the correct answer as it is the initial molecule in the pathway of fatty acid synthesis.

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  • 10. 

    The conversion of acetyl CoA to malonyl CoA is the rate-limiting step in fatty acid synthesis. Which of the following enzyme catalyzes the above mentioned reaction?

    • A.

      Acetyl CoA carboxylase

    • B.

      Malonyl CoA synthetase

    • C.

      Acetyl CoA decarboxylase

    • D.

      Malonyl CoA synthase

    Correct Answer
    A. Acetyl CoA carboxylase
    Explanation
    Acetyl CoA carboxylase is the enzyme that catalyzes the conversion of acetyl CoA to malonyl CoA, which is the rate limiting step in fatty acid synthesis. This enzyme adds a carboxyl group to acetyl CoA, resulting in the formation of malonyl CoA. This step is important in controlling the overall rate of fatty acid synthesis, as it determines the availability of malonyl CoA, which is a key precursor for fatty acid production.

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Farah Naz |MBBS, Medicine |
Medical Expert
Farah holds a Bachelor of Medicine and Bachelor of Surgery (MBBS) from Dow University of Health Sciences. She gained valuable experience through internships in Radiology, Cardiology, and Neurosurgery, and has contributed to two research publications in medical journals. Passionate about healthcare education, Farah excels in crafting medical content, including articles, literature reviews, and e-learning courses. Leveraging her expertise, she meticulously reviews medical science quizzes, ensuring accuracy and educational value for aspiring healthcare professionals.

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  • Current Version
  • Feb 20, 2024
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    Expert Reviewed by
    Farah Naz
  • Jul 04, 2016
    Quiz Created by
    KUFAMEDST
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