Explore the intricacies of lipid metabolism with this quiz focused on diseases and biochemical processes involving membrane lipids. Assess your understanding of genetic conditions, lipid transport mechanisms, and enzyme functions relevant to health sciences.
By reducing the synthesis of apo B-100, the major structural protein of VLDL and LDL
By stimulating the conversion of excess cholesterol to bile acids in the liver, thereby depleting cholesterol for LDL synthesis
By stimulating the transfer of cholesterol esters from VLDL and LDL to HDL
By inhibiting HMG-CoA reductase, thereby preventing cholesterol synthesis and forcing the cells to obtain their cholesterol from LDL
By stimulating the efflux of free cholesterol from cell membranes to HDL, thereby reducing the amount of cholesterol that is partitioned into LDL
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Add cholesterol esters to the medium
Add excess LDL to the medium
Inhibit HMG-CoA reductase
Inhibit the activity of acyl-CoA-cholesterol-acyl transferase (ACAT)
Add cholestyramine
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Fabry's disease
Niemann-Pick disease
Krabbe's disease
Gaucher's disease
Hurler syndrome
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Integral membrane proteins
Glycosyl transferases
Peripheral membrane proteins
Cytoskeletal proteins
Phosphoglyceride-synthesizing enzymes
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Heme
Purines
Pyrimidines
Ketone bodies
Glutathione
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A low ratio of free cholesterol/cholesterol esters
An elevated glucose level
A low lecithin/shingomyelin ratio
An elevated level of phosphatidylglycerol
A reduced level of platelet-activating factor
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Enhanced VLDL formation in the liver
Down-regulation of HMG-CoA reductase
Higher lipoprotein lipase (LPL) activity
Higher plasma chylomicron concentration
An increased number of LDL receptors
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IDL
LDL
HDL
VLDL
Lipoprotein(a)
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Cholesterol ester transfer protein
Acyl-CoA-cholesterol acyltransferase (ACAT)
7a-hydroxylase
HMG-CoA reductase
Lecithin-cholesterol acyltransferase (LCAT)
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Type I
Type V
Type III
Type IV
Type IIa
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Look for eruptive xanthomas
Do a VLDL analysis
Isolate the patient's lymphocytes and look for the number of LDL receptors
Check for hyperthyroidism
Do a fasting blood glucose
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Type I
Type III
Type IIb
Type IIa
Type IV
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A-I
C-II
B-100
C-III
E
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