What do you know about gluconeogenesis? The brain needs energy to operate and the main source for this energy is found in glucose which we consume from other foods. Glucose is produced when the food is broken down. Do take up this quiz and see what you know about how glucose is produced and using which enzymes. All the best and see what new facts you might learn in the process.
Lactate
Alanine
Glycerol
Acetly CoA
Glucose-6-phosphatase
Fructose-1,6-Bisphosphatase
Phosphoenol pyruvate carboxykinase
Pyruvate carboxylase
This reaction involves two step process catalyzed by pyruvate carboxylase and phosphoenolpyruvate caboxykinase
Conversion of oxaloacetate from pyruvate occurs in mitochondria and shuttled into cytosol.
Phosphoenol pyruvate utilizes both ATP and GTP as energy source.
Acetly CoA is an activator of enzyme pyruvate carboxylase.
Conversion of glucose-6-phosphate to glucose releases one ATP molecule
It is highly active enzyme in skeletal muscle
Defect in glucose-6-phosphatase leads to abnormal accumulation of glycogen in liver
The reaction occurs in mitochondria
Insulin
Glucogon
TSH
Thyroxine
Muscles have a large glycogen store which gives rise to blood glucose during prolonged starvation.
Fatty acids are plentiful in the blood during starvation and are used for glucose synthesis.
The enzyme glucose-6-phosphatase hydrolyses glucose-6-phosphate and is present in most cells.
Gluconeogenesis enables the liver to maintain blood glucose levels during starvation
Brain can use fatty acids for all its energy needs.
Red blood cells can use fatty acids for all their energy needs.
The brain can use ketone bodies for all its energy needs.
The brain can use glucose for all its energy needs.
In gluconeogenesis, pyruvate is first converted to phosphoenolpyruvate by phosphoenolpyruvate carboxykinase.
In gluconeogenesis fructose-1:6-bisphosphatase converts fructose-1:6-bisphosphate into fructose-1-phosphate.
Glucose-6-phosphatase hydrolyses glucose-6-phosphate to release glucose into the blood.
Glucose-6-phosphatase hydrolyses glucose-6-phosphate and is found in liver and muscle.
The main source of glucose carbons for gluconeogenesis is pyruvate synthesised from acetyl-CoA.
The main source of glucose carbons for gluconeogenesis is alanine derived from breakdown of muscle proteins.
The main source of glucose carbons cannot occur from muscles as they do not undergo gluconeogenesis.
The main source of glucose carbons in gluconeogenesis is pyruvate released from muscles
The metabolism of ethanol by the liver decreases the NADH/NAD+ ratio reducing its ability to perform gluconeogenesis.
The reduction of ethanol by the liver increases the NADH/NAD+ ratio reducing its ability to perform gluconeogenesis.
The oxidation of ethanol by the liver increases the NADH/NAD+ ratio increasing its ability to perform gluconeogenesis.
The metabolism of ethanol by the liver increases the NADH/NAD+ ratio reducing its ability to perform gluconeogenesis.
Lactate from muscle vigorous muscle activity can be used as a carbon source in gluconeogenesis.
Glycerol from the hydrolysis of triacylglycerols is converted to glucose in gluconeogenesis.
Lactate from red blood cells can be used as a carbon source in gluconeogenesis.
Fatty acids from the hydrolysis of triacylglycerols can be used as a carbon source in gluconeogenesis.
Gluconeogenesis is the formation of glucose from glycogen.
Glucose may be stored as glycogen or converted to fat.
Glycogenolysis and gluconeogenesis are functions of the liver.
Gluconeogenesis is stimulated when plasma glucose is low.
Glycogenesis is stimulated when cellular ATP reserves are low.
Ketosis
Hexoses
Pentoses
None of above
12
11
13
10
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