Quiz: Preparation Storage And Characteristics Of Blood & Its Components

31 Questions | By Jensley | Last updated: Aug 26, 2022 | Total Attempts: 1463

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Quiz: Preparation Storage And Characteristics Of Blood & Its Components - Quiz

Are you well aware of the preparation, storage, and characteristics of blood & its components? This quiz is here to see how much do you know. Blood is essential for transporting essential nutrients to all parts of the body. Human blood comprises many different cell types (RBC, WBC, Platelets, etc. ) The quiz will test your knowledge of the laboratory storage & preparation of blood samples. Read all the given questions carefully. If you have any doubts about any questions, you can refer to your notes for help. All the questions are designed to help you prepare better for the exams. Attempt all the questions given below. Good luck!

Questions and Answers

1.

The correct temperature for shipping RBCs is
- A.
  
  1 to 6C
- B.
  
  1 to 10C
- C.
  
  20 to 24C
- D.
  
  37C
2.

RBC storage times vary with the anticoagulant/preservative used. Which of the following is properly paired?
- A.
  
  Citrate-phosphate-dextrose (CPD): 35 days
- B.
  
  Additive solution (AS): 47 days
- C.
  
  Citrate-phosphate-dextrose-adenine (CPDA)-1: 21 days
- D.
  
  Acid-citrate-dextrose (ACD): 35 days
- E.
  
  Citrate-phosphate-dextrose-dextrose (CP2D): 21 days
3.

Which of the following represents a change seen in a unit of RBCs stored with CPDA-1 at the end of its shelf life?
- A.
  
  Percentage of viable cells at 24 hours after transfusion decreases to 71%
- B.
  
  Supernatant K+ (potassium ion) concentration decreases
- C.
  
  Supernatant pH increases
- D.
  
  Red cell 2, 3-DPG increases
- E.
  
  Supernatant hemoglobin decreases
4.

A unit of RBCs is issued to the floor and returned without being transfused. How long can blood be out of the refrigerator and still be used for transfusion?
- A.
  
  10 minutes
- B.
  
  30 minutes
- C.
  
  1 hour
- D.
  
  4 hours
- E.
  
  6 hours
5.

The maximal shelf life of irradiated RBCs is :
- A.
  
  4 hours
- B.
  
  6 hours
- C.
  
  24 hours
- D.
  
  21 days
- E.
  
  28 days
6.

The preferred method for generating leukocyte- reduced RBC components is:
- A.
  
  Thawing and deglycerolizing a frozen unit
- B.
  
  Filtering using a leukocyte-reduction filter
- C.
  
  Irradiation
- D.
  
  Centrifugation
- E.
  
  Washing
7.

The most common concentration of glycerol used in the U.S. for freezing RBCs is:
- A.
  
  5%
- B.
  
  10%
- C.
  
  20%
- D.
  
  40%
- E.
  
  65%
8.

The rationale for deglycerolizing frozen RBCs with extensive washing is:
- A.
  
  Glycerol is not approved by the FDA
- B.
  
  Glycerol is toxic to kidneys
- C.
  
  Glycerol can cause hemolysis
- D.
  
  Glycerol can cause anaphylaxis
- E.
  
  Glycerol can cause thrombocytopenia
9.

Which of the following choices explains why a unit of blood may form an insoluble jelly-like mass during deglycerolization?
- A.
  
  Inadequate deglycerolization
- B.
  
  Bacterial contamination
- C.
  
  Insufficient anticoagulant
- D.
  
  Inadvertent use of hypotonic saline for washing
- E.
  
  Red cells from a donor with sickle cell trait
10.

Two S-s-U- units are deglycerolized in preparation for possible transfusion. The patient, however, is stabilized and transfusion is no longer required. The medical director should:
- A.
  
  Refrigerate the units until the expiration time and discard if not clinically needed
- B.
  
  Advise the medical staff to transfuse the units because they are rare
- C.
  
  Document the value of the antigen-negative units and refreeze for up to another 10 years
- D.
  
  Release the rare units so that they can be made available for another patient
11.

According to the AABB standards, the maximum allowable shelf-life of platelets without gentle agitation is:
- A.
  
  1 hour
- B.
  
  4 hours
- C.
  
  8 hours
- D.
  
  24 hours
- E.
  
  36 hours
12.

According to AABB standards, 90% of the units of random-donor platelets prepared from whole blood should contain a minimum of _______ platelets per unit.
- A.
  
  5.5 x 10^ 9
- B.
  
  5.5 x 10 ^ 10
- C.
  
  5.5 x 10 ^11
- D.
  
  3 x 10 ^ 10
- E.
  
  3 x 10 ^ 11
13.

The minimum acceptable pH of platelet units at the end of the storage period is:
- A.
  
  4.2
- B.
  
  5.2
- C.
  
  6.2
- D.
  
  7.2
- E.
  
  8.2
14.

Which of the following is a change associated with platelet storage?
- A.
  
  Decreased H+ concentration
- B.
  
  Platelet activation
- C.
  
  Change in shape from round to discoid
- D.
  
  Increased swirling effect
- E.
  
  Increased expression of glycoprotein Ib and glycoprotein IIb/IIIa
15.

Transfusion of one platelet concentrate (ie the platelets present in one whole blood donation) into a hematologically stable adult of average size with no history of transfusion and/or pregnancy is expected to increase the platelet count by:
- A.
  
  1000 to 5000 /uL
- B.
  
  3000 to 5000 /uL
- C.
  
  3000 to 12000 /uL
- D.
  
  5000 to 10000/ uL
- E.
  
  30000 to 40000 .uL
16.

Which of the following is a theoretical advantage associated with transfusion of a whole-blood derived pooled-platelet unit compared with an apheresis platelet unit?
- A.
  
  Decreased donor exposure for infectious disease transmission
- B.
  
  Decreased risk of TRALI
- C.
  
  Decreased donor exposure for HLA alloimmunization
- D.
  
  Decreased risk of septic transfusion reaction
- E.
  
  All of the above
17.

FFP that has been thawed and is being stored at 1 to 6 C should be transfused within
- A.
  
  4 hours
- B.
  
  6 hours
- C.
  
  12 hours
- D.
  
  18 hours
- E.
  
  24 hours
18.

Which of the following is true?
- A.
  
  To prepare FFP plasma must be separated from red cells within 24 hours
- B.
  
  If an additive solution is used, the expiration date for RBCs stored at 1 to 6 C is 42 days after phlebotomy
- C.
  
  To prepare Cryo FFP is thawed at 20 to 24 C
- D.
  
  Platelets derived from a unit of whole blood must contain 3 x 10 ^ 11 platelets in 75% of units released
- E.
  
  The expiration date of RBCs that are frozen and stored at
19.

A group B Rh positive patient requires FFP. Group B FFP is not available. The substitute component of choice is:
- A.
  
  Group O FFP
- B.
  
  Group B, Rh positive cryo
- C.
  
  Group A FFP
- D.
  
  Group AB FFP
- E.
  
  Group A, Rh negative cryo
20.

Which of the following is true?
- A.
  
  Cryo can be made from cryo-reduced plasma (CRP) or FFP
- B.
  
  CRP can not be used in manufacturing albumin and immunoglobulins
- C.
  
  CRP and cryo can not be prepared from FFP collected by apheresis
- D.
  
  CRP is rich in fibrinogen, factor VIII, and vWF
- E.
  
  CRP is deficient in ADAMTS13
21.

Cryo should be stored at
- A.
- B.
  
  1 to 6 C
- C.
  
  20 to 22C
- D.
  
  30 C
- E.
  
  37C
22.

After thawing cryo should be stored at:
- A.
  
  42C
- B.
  
  37C
- C.
  
  20 to 24 C
- D.
  
  1 to 6 C
- E.
  
  -18 C
23.

According to AABB standards each bag of cryo must contain a minimum of how many Internation Units of Factor VIII?
- A.
  
  70
- B.
  
  80
- C.
  
  100
- D.
  
  120
- E.
  
  150
24.

Cryo contains which of the following?
- A.
  
  Factor XI
- B.
  
  Protein C
- C.
  
  Protein S
- D.
  
  Factor XIII
- E.
  
  Factor XII
25.

Which is true regarding cryo?
- A.
  
  Is prepared from FFP thawed at 20 to 24C
- B.
  
  Once thawed is stored at 1 to 6 C and given within 6 hours of thawing or 4 hours of pooling
- C.
  
  It is prepared by filtering thawed FFP at 1 to 6 C
- D.
  
  It is prepared by centrifuging thawed FFP at 1 to 6 C
- E.
  
  Thawed cryo is stored at 1 to 6 C during transport