Blood Components: Preparation, Storage And Characteristics

31 Questions | Total Attempts: 470

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Blood Quizzes & Trivia

Questions and Answers
  • 1. 
    The correct temperature for shipping RBCs is
    • A. 

    • B. 

      1 to 6C

    • C. 

      1 to 10C

    • D. 

      20 to 24C

    • E. 

      37C

  • 2. 
    RBC storage times vary with the anticoagulant/preservative used.  Which of the following is properly paired?
    • A. 

      Citrate-phosphate-dextrose (CPD): 35 days

    • B. 

      Additive solution (AS): 47 days

    • C. 

      Citrate-phosphate-dextrose-adenine (CPDA)-1: 21 days

    • D. 

      Acid-citrate-dextrose (ACD): 35 days

    • E. 

      Citrate-phosphate-dextrose-dextrose (CP2D): 21 days

  • 3. 
    Which of the following represents a change seen in a unit of RBCs stored with CPDA-1 at the end of its shelf life?
    • A. 

      Percentage of viable cells at 24 hours after transfusion decreases to 71%

    • B. 

      Supernatant K+ (potassium ion) concentration decreases

    • C. 

      Supernatant pH increases

    • D. 

      Red cell 2, 3-DPG increases

    • E. 

      Supernatant hemoglobin decreases

  • 4. 
    • A. 

      10 minutes

    • B. 

      30 minutes

    • C. 

      1 hour

    • D. 

      4 hours

    • E. 

      6 hours

  • 5. 
    The maximal shelf life of irradiated RBCs is :
    • A. 

      4 hours

    • B. 

      6 hours

    • C. 

      24 hours

    • D. 

      21 days

    • E. 

      28 days

  • 6. 
    The preferred method for generating leukocyte- reduced RBC components is:
    • A. 

      Thawing and deglycerolizing a frozen unit

    • B. 

      Filtering using a leukocyte-reduction filter

    • C. 

      Irradiation

    • D. 

      Centrifugation

    • E. 

      Washing

  • 7. 
    The most common concentration of glycerol used in the U.S. for freezing RBCs is:
    • A. 

      5%

    • B. 

      10%

    • C. 

      20%

    • D. 

      40%

    • E. 

      65%

  • 8. 
    The rationale for deglycerolizing frozen RBCs with extensive washing is:
    • A. 

      Glycerol is not approved by the FDA

    • B. 

      Glycerol is toxic to kidneys

    • C. 

      Glycerol can cause hemolysis

    • D. 

      Glycerol can cause anaphylaxis

    • E. 

      Glycerol can cause thrombocytopenia

  • 9. 
    Which of the following choices explains why a unit of blood may form an insoluble jelly-like mass during deglycerolization?
    • A. 

      Inadequate deglycerolization

    • B. 

      Bacterial contamination

    • C. 

      Insufficient anticoagulant

    • D. 

      Inadvertent use of hypotonic saline for washing

    • E. 

      Red cells from a donor with sickle cell trait

  • 10. 
    Two S-s-U- units are deglycerolized in preparation for possible transfusion.  The patient, however, is stabilized and transfusion is no longer required.  The medical director should:
    • A. 

      Refrigerate the units until the expiration time and discard if not clinically needed

    • B. 

      Advise the medical staff to transfuse the units because they are rare

    • C. 

      Document the value of the antigen-negative units and refreeze for up to another 10 years

    • D. 

      Release the rare units so that they can be made available for another patient

  • 11. 
    According to the AABB standards, the maximum allowable shelf-life of platelets without gentle agitation is:
    • A. 

      1 hour

    • B. 

      4 hours

    • C. 

      8 hours

    • D. 

      24 hours

    • E. 

      36 hours

  • 12. 
    According to AABB standards, 90% of the units of random-donor platelets prepared from whole blood should contain a minimum of _______ platelets per unit.
    • A. 

      5.5 x 10^ 9

    • B. 

      5.5 x 10 ^ 10

    • C. 

      5.5 x 10 ^11

    • D. 

      3 x 10 ^ 10

    • E. 

      3 x 10 ^ 11

  • 13. 
    The minimum acceptable pH of platelet units at the end of the storage period is:
    • A. 

      4.2

    • B. 

      5.2

    • C. 

      6.2

    • D. 

      7.2

    • E. 

      8.2

  • 14. 
    Which of the following is a change associated with platelet storage?
    • A. 

      Decreased H+ concentration

    • B. 

      Platelet activation

    • C. 

      Change in shape from round to discoid

    • D. 

      Increased swirling effect

    • E. 

      Increased expression of glycoprotein Ib and glycoprotein IIb/IIIa

  • 15. 
    Transfusion of one platelet concentrate  (ie the platelets present in one whole blood donation) into a hematologically stable adult of average size with no history of transfusion and/or pregnancy is expected to increase the platelet count by:
    • A. 

      1000 to 5000 /uL

    • B. 

      3000 to 5000 /uL

    • C. 

      3000 to 12000 /uL

    • D. 

      5000 to 10000/ uL

    • E. 

      30000 to 40000 .uL

  • 16. 
    Which of the following is a theoretical advantage associated with transfusion of a whole-blood derived pooled-platelet unit compared with an apheresis platelet unit?
    • A. 

      Decreased donor exposure for infectious disease transmission

    • B. 

      Decreased risk of TRALI

    • C. 

      Decreased donor exposure for HLA alloimmunization

    • D. 

      Decreased risk of septic transfusion reaction

    • E. 

      All of the above

  • 17. 
    FFP that has been thawed and is being stored at 1 to 6 C should be transfused within
    • A. 

      4 hours

    • B. 

      6 hours

    • C. 

      12 hours

    • D. 

      18 hours

    • E. 

      24 hours

  • 18. 
    Which of the following is true?
    • A. 

      To prepare FFP plasma must be separated from red cells within 24 hours

    • B. 

      If an additive solution is used, the expiration date for RBCs stored at 1 to 6 C is 42 days after phlebotomy

    • C. 

      To prepare Cryo FFP is thawed at 20 to 24 C

    • D. 

      Platelets derived from a unit of whole blood must contain 3 x 10 ^ 11 platelets in 75% of units released

    • E. 

      The expiration date of RBCs that are frozen and stored at

  • 19. 
    A group B Rh positive patient requires FFP.  Group B FFP is not available.  The substitute component of choice is:
    • A. 

      Group O FFP

    • B. 

      Group B, Rh positive cryo

    • C. 

      Group A FFP

    • D. 

      Group AB FFP

    • E. 

      Group A, Rh negative cryo

  • 20. 
    Which of the following is true?
    • A. 

      Cryo can be made from cryo-reduced plasma (CRP) or FFP

    • B. 

      CRP can not be used in manufacturing albumin and immunoglobulins

    • C. 

      CRP and cryo can not be prepared from FFP collected by apheresis

    • D. 

      CRP is rich in fibrinogen, factor VIII, and vWF

    • E. 

      CRP is deficient in ADAMTS13

  • 21. 
    Cryo should be stored at
    • A. 

    • B. 

      1 to 6 C

    • C. 

      20 to 22C

    • D. 

      30 C

    • E. 

      37C

  • 22. 
    After thawing cryo should be stored at:
    • A. 

      42C

    • B. 

      37C

    • C. 

      20 to 24 C

    • D. 

      1 to 6 C

    • E. 

      -18 C

  • 23. 
    According to AABB standards each bag of cryo must contain a minimum of how many Internation Units of Factor VIII?
    • A. 

      70

    • B. 

      80

    • C. 

      100

    • D. 

      120

    • E. 

      150

  • 24. 
    Cryo contains which of the following?
    • A. 

      Factor XI

    • B. 

      Protein C

    • C. 

      Protein S

    • D. 

      Factor XIII

    • E. 

      Factor XII

  • 25. 
    Which is true regarding cryo?
    • A. 

      Is prepared from FFP thawed at 20 to 24C

    • B. 

      Once thawed is stored at 1 to 6 C and given within 6 hours of thawing or 4 hours of pooling

    • C. 

      It is prepared by filtering thawed FFP at 1 to 6 C

    • D. 

      It is prepared by centrifuging thawed FFP at 1 to 6 C

    • E. 

      Thawed cryo is stored at 1 to 6 C during transport