Block 9 Vaccines Abx Infxn Cntrl And Ethics MCQ's

17 Questions | Total Attempts: 279

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Ethics Quizzes & Trivia

Questions and Answers
  • 1. 
    What type of immunity is protective against Haemophilus influenzae type b?
    • A. 

      Antibodies and complement

    • B. 

      Antibodies and phagocytes

    • C. 

      T cells and macrophages

    • D. 

      IgE and mast cells

    • E. 

      There is no protective immune response

  • 2. 
    A new virus, the Semester 3-induced Hysteria virus (SIFIV) has been discovered, This virus is oncogenic, causing brain tumors, and establishes latency in certain individuals. Most individuals who experience natural infection become protected from subsequent infection via the production of antibodies. These antibodies recognize a conformational epitope comprised of the juxtaposition of 2 capsid proteins on the surface of the virus. A vaccine for this virus is underway. Which type of vaccine would be best for this virus?
    • A. 

      Live attenuated

    • B. 

      Formalin-inactivated viral particles

    • C. 

      Subunit vaccine comprised of the 2 recombinantly expressed capsid proteins

    • D. 

      A hybrid vaccine consisting of the 2 capsid genes inserted into vaccinia virus

  • 3. 
    A new virus, Grouch Papilloma Virus, has been isolated from a Grouch population living in a small community in New York City. While primary infection is largely asymptomatic, the virus is known to establish latency and causes sduamous cell carcinoma in a high proportion of latently infected patients. Development of a vaccine is underway. Why would an inactivated vaccine be a better choice than a live vaccine for this organism?
    • A. 

      Inactivated vaccines are strong stimulators of cell-mediated immunity

    • B. 

      Live organisms in live vaccines have no chance of establishing latency

    • C. 

      Inactivated vaccines are always the best choice for viruses.

    • D. 

      With an inactivated vaccine, there is no need for booster shots.

    • E. 

      With an inactivated vaccine, there is no risk for the organism to drive oncogenesis.

  • 4. 
    Which of the following vaccines contain toxoids?
    • A. 

      Trivalent influenza A and influenza B

    • B. 

      Measles, mumps,rubella

    • C. 

      Haemophilus influenzae type b

    • D. 

      Pneumococcal polysaccharide vaccine

    • E. 

      Diphtheria, tetanus, pertussis

  • 5. 
    Describe the content of the smallpox vaccine
    • A. 

      Live, dsDNA virus derived from variola virus

    • B. 

      Live, dsDNA virus derived from vaccinia virus

    • C. 

      Killed, dsDNA virus derived from the smallpox virus

    • D. 

      Killed, clsRNA virus derived from smallpox virus

    • E. 

      Component surface antigen of smallpox virus

    • F. 

      Attenuated dsRNA virus derived from cowpox virus

  • 6. 
    The vaccine for Anthrax is a killed cell vaccine. Because of the fact that this vaccine is comprised of killed organism, what is a disadvantage of the vaccine?
    • A. 

      There is a risk that the vaccine components will secrete the toxins that cause the disease.

    • B. 

      The immunity to the organism will wane as soon as the vaccine components are cleared from the body

    • C. 

      This vaccine is not appropriate for use in immuncompromised persons

    • D. 

      Immunity to this organism is not typically life-long and sustained immunity will require booster shots.

    • E. 

      Maintaining viability of the vaccine is a concern

  • 7. 
    A 69-year-old man recently diagnosed with a Proteus mirabilis infection started a treatment with a daily 1M injection of gentamicin, an aminoglycoside antibiotic. Which of the following pairs of properties best explains why the drug is usually administered once daily despite the short half-life of gentamicin (about two hours)?
    • A. 

      Time-dependent killing and bactericidal effect

    • B. 

      Extensive plasma protein binding and bactericidal effect

    • C. 

      Dose-dependent renal impairment and bacteriostatic effect

    • D. 

      Concentration-dependent killing and long post antibiotic effect

    • E. 

      Time-dependent killing and long post antibiotic effect

  • 8. 
    Which of the following is true regarding innate immunity?
    • A. 

      It provides only weak non-specific responses to pathogens

    • B. 

      It operates uniquely at body surfaces

    • C. 

      It provides rapid immunity and influences acquired immunity

    • D. 

      It involves cells but not secreted proteins

    • E. 

      It does not require signaling events

  • 9. 
    Innate immune responses are like adaptive immunity in that they
    • A. 

      Are antigen-specific

    • B. 

      Demonstrate immune memory

    • C. 

      Involve macrophages and complement

    • D. 

      Involve T lymphocytes

    • E. 

      Involve B lymphocytes

  • 10. 
    This 40 year old patient is complaining of chest pain which begins on the left side of the chest. On occasion the pain radiates up into the jaw area and down his left arm. You explain that this is the pain of angina pectoris which suggests narrowing of the blood vessels of the heart. You suggest that he takes cardiac catherization to establish the diagnosis. He adamantly refuses, "I am too young for that." Your best ethical course of action is?
    • A. 

      Call his wife and explain the situation to her.

    • B. 

      Bow to the patient's decision respectfully and do nothing.

    • C. 

      Call a meeting of the entire family in his absence, detailing the situation and solicit their help in convincing him to agree to your request.

    • D. 

      Let the Ethics Committee decide

    • E. 

      Approach the court with an order forcing him for his and his family's welfare to cooperate.

  • 11. 
    This 90 year old man is brought into the emergency room after a motor vehicle accident. He sustained bilateral fractured ribs and is in respiratory distress because of bilateral pneumothoraces (Pneunornothorax). He is conscious though, but failing fast. He needs to be intubated immediately. His wife calls and tells you that she is on her way with his living will which states that he does not want any heroic measures if he is near death, which in essence he is. What is your best ethical course of action?
    • A. 

      Delay intubation until the wife arrives with the living will

    • B. 

      Move promptly and intubate your patient in the hope that is life will be saved

    • C. 

      Call the other family members and get their opinion

    • D. 

      Even though he is in distress, request from him what he now wants to be done,

    • E. 

      Defer to the advice of the Ethics Committee

  • 12. 
    Your schizophrenic patient confides in you that he has been hearing voices warning him for weeks now that his parents are trying to kill him. He has now concluded, "I think I will get rid of them before they get rid of me. In fact I will poison them tonight.' How do you manage this situation involving this 16 year old boy?
    • A. 

      Ignore the comment because you are sure he will not get rid of these two persons on whom he completely depends.

    • B. 

      Immediately admit him to the hospital involuntarily, get an immediate Psychiatry consut and restrain him if necessary.

    • C. 

      Discuss the situation with him, finally adding "Both your parents love you, you shou!d not talk this way."

    • D. 

      Do not admit him to the hospital but get a Psychiatry consult for two (2) days time

    • E. 

      Inform the police but do not inform the parents for both fear of breaching confidentiality and unnecessarily causing them concern.

  • 13. 
    A male patient is hospitalized while in a diabetic coma. Medical records and information provided by the patient's wife indicate a long-standing history of uncontrolled diabetes mellitus. Examination of the patient reveals a gangrenous right leg. if the leg is not immediately amputated, the patient will die. What is the most reasonable and ethical next step for the physician to take?
    • A. 

      Amputate the leg immediately without the patient's consent

    • B. 

      Do nothing until the patient is competent to provide consent

    • C. 

      Exercise the doctrine of substituted judgment.

    • D. 

      Exercise the doctrine of best interest

  • 14. 
    A former patient calls you on the phone and expresses their interest to pursue a personal and intimate relationship with you. They further express a very strong attraction to your caring, gentle, and highly competent manner of relating to patients. The most ethical manner of dealing with this patient is to:
    • A. 

      Feel free to reciprocate if interested

    • B. 

      Feel free to reciprocate if you have not seen this patient for at least one year

    • C. 

      Consult with a colleague before making a decision.

    • D. 

      Respectfully decline the offer while allowing the patient to maintain integrity.

    • E. 

      It depends on how hot she is

  • 15. 
    Your 68 year old male patient is hospitalized for a gangrenous right leg secondary to his longstanding history of uncontrolled diabetes mellitus. You inform him that amputation is essential in order to preserve his life. He refuses to consent to such intervention and informs you that he would rather die than be without a leg. What is the most reasonable next step for you to take?
    • A. 

      Proceed with the surgery

    • B. 

      Report him to his family

    • C. 

      Simply leave him alone and respect his wishes

    • D. 

      Order a consult for a competency evaluation

  • 16. 
    Due to a psychotic episode your 24 year old female patient, who believes you are conducting medical experiments on her, refuses to undergo critical diagnostic tests for a suspected carcinoma of the lung. The tests you intend to perform are the least intrusive means of determining her medical condition, a condition that could be life-threatening. It has been determined that she is not competent to make decisions regarding her medical care. The most reasonable next step would be to:
    • A. 

      Immediately proceed with diagnostic testing,

    • B. 

      Attempt to determine what is in the best interest of the patient

    • C. 

      Wait and hope that her psychosis abates and competency is restored

    • D. 

      Determine from the family what she would have wished had she been competent.

  • 17. 
    You are socializing with some friends at a nightclub when a very attractive patient, whom you examined two days previously, approaches you and whispers in your ear that they cannot stop thinking about you and wishes to get to know you better. They even tell you that they are so interested in you that they intend to no longer be your patient so you can be free to pursue something with them. You feel quite flattered, excited, and interested. The most ethical course of action would be to:
    • A. 

      Wait two years and then make a decision

    • B. 

      Consult with your attorney

    • C. 

      Respectfully decline the offer while allowing patient to maintain integrity

    • D. 

      Feel free to pursue a relationship as they are no longer your patient.

    • E. 

      If she is really hot, it would be ok, just this one time