Respiratory Pharmacology

10 Questions | By Chachelly | Last updated: Nov 12, 2016

Settings

Share This on Twitter

Email

Pin it

Share on reddit

- +

Respiratory Pharmacology Quizzes & Trivia

.

Questions and Answers

1.

A 59-year-old man complained to his physician of increasing dyspnea over the last few days. The man had a 3-year history of chronic obstructive pulmonary disease and had been suffering from gastric ulcer for the last six months. Inhalational therapy with albuterol had to be suspended for the appearance of tremors. Which of the following drug treatments would be appropriate for this patient?

Discuss
- A.
  
  Oral theophylline
- B.
  
  Inhaled salmeterol
- C.
  
  Inhaled ipratropium
- D.
  
  Inhaled cromolyn
- E.
  
  Oral triamcinolone
- F.
  
  Oral zafirlukast
2.

A 32-year-old female with mild intermittent asthma was successfully maintained on an inhaled antiasthmatic drug “as needed”. Which of the following molecular actions most likely mediated the therapeutic effectiveness of that drug in the patient’s disease?

Discuss
- A.
  
  Blockade of histamine release from bronchial epithelium
- B.
  
  Blockade of leukotriene receptors in bronchial muscle
- C.
  
  Release of nitric oxide from bronchial epithelium
- D.
  
  Increased cAMP in bronchial muscle
- E.
  
  Activation of beta-2 receptors in bronchial vessels
3.

43-year old African-American man presented to his physician complaining of an increasing cough productive of yellow sputum and of moderate shortness of breath on exertion. The man had a long history of heavy cigarette smoking and suffered from an episode of sustained ventricular tachycardia one year ago. Physical examination showed a patient with shallow breathing and a barrel chest. Auscultation demonstrated wheezing and distant heart sounds. An inhalational therapy was ordered. A drug with which of the following mechanism of action was most likely prescribed?

Discuss
- A.
  
  Blockade of adenosine receptors
- B.
  
  Inhibition of phospholipase A2
- C.
  
  Activation of beta-2 receptors
- D.
  
  Blockade of Nn and M3 receptors
4.

A 52-year-old man was admitted to the hospital with an asthmatic attack. The man had been suffering from seasonal asthma for one year. On questioning he mentioned that he took two tablets of aspirin for a headache the previous evening. An appropriate therapy was instituted, and he was discharged from the hospital. Which of the following drugs was most likely included in his post discharge therapy?

Discuss
- A.
  
  Oral zafirlukast
- B.
  
  Oral triamcinolone
- C.
  
  Inhaled ipratropium
- D.
  
  Oral theophylline
5.

A 36-year-old woman complained to her physician of mucoid cough and breathlessness of one month duration. She currently smoked one pack of cigarettes daily. Spirometry showed an FEV1 of 50% of the predicted value. The physician prescribed inhaled albuterol as needed. Which of the following adverse effects would the patient most likely experience?
- A.
  
  Impairment of far vision
- B.
  
  Sialorrhea
- C.
  
  Tachycardia
- D.
  
  Uterine cramps
6.

A 9-year-old boy with moderate persistent asthma visited chest clinic for follow-up of his condition. He has only been moderately controlled on oral sustained-release theophylline and montelukast daily, and inhaled albuterol “as needed”. On physical examination he has diffuse expiratory wheezes. His peak expiratory flow rate is 60% of the predicted value. Which of the following would be the most appropriate therapeutic conduct for this patient at this point?

Discuss
- A.
  
  Substitute ipratropium for albuterol
- B.
  
  Substitute inhaled budesonide for theophylline
- C.
  
  Substutute zafirlukast for montelukast
- D.
  
  Substitute inhaled isoproterenol for albuterol
- E.
  
  Substitute salmeterol for albuterol
7.

A 56-year-old man presents with chronic mucoid cough and breathlessness of one month duration. He has an 80-pack-year smoking history and currently smokes one pack/day. Spirometry shows that his FEV1 is 50% of the predicted value. The physician decides to start therapy with ipratropium bromide through a metered dose inhaler. The beneficial effect of the drug in this disease is most likely due to the blockade of which of the following pairs of receptors in the bronchial tree?

Discuss
- A.
  
  Histamine H1 and nicotinic Nn
- B.
  
  Histamine H1 and muscarinic M3
- C.
  
  Nicotinic Nn and muscarinic M3
- D.
  
  Nicotinic Nn and adrenergic alpha-1
- E.
  
  Muscarinic M1 and adrenergic beta-2
8.

Which of the following conditions can decrease the clearance of theophylline?

Discuss
- A.
  
  Concomitant zileuton treatment
- B.
  
  Hyperthyroidism
- C.
  
  Smoking
- D.
  
  Concomitant rifampin treatment
- E.
  
  Concomitant phenytoin treatment
9.

A premature newborn baby of 29 weeks gestational age developed five episodes of apnea on the second day of life. The apnea episodes lasted for 20 to 30 seconds and required administration of oxygen. Three prolonged episodes required bag and mask ventilation. He was given an intravenous drug to manage apnea. Which of the following drugs was most likely administered to him?

Discuss
- A.
  
  Epinephrine
- B.
  
  Albuterol
- C.
  
  Theophylline
- D.
  
  Atropine
- E.
  
  Zafirlukast
10.

A 67-year old man is admitted to the hospital for exacerbation of his chronic obstructive pulmonary disease. He is currently intubated and receiving high dose albuterol therapy by continuous nebulization. Which of the following is serious adverse effect that can develop with this treatment?

Discuss
- A.
  
  Miosis
- B.
  
  Constipation
- C.
  
  Bradycardia
- D.
  
  Hypoglycemia
- E.
  
  Hypokalemia

Back to top

More Respiratory Pharmacology Quizzes

Featured Quizzes

Related Topics

Back to top