Venil's Pathology Finals Review Questions 1

30 Questions | By Addju1 | Updated: Mar 17, 2022 | Attempts: 111

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Venils Pathology Finals Review Questions 1 - Quiz

This is the first of a series of online quizzes made by Venil Bolambao for students taking General Pathology in order to gauge their knowledge in preparation for the upcoming finals exam. There are 30 questions, all MCQ. Good luck and God bless!

Questions and Answers

1.

All of the following are gene & gene products that regulate apoptosis, EXCEPT:
- A.
  
  Bcl-2
- B.
  
  P53
- C.
  
  Bcr-abl
- D.
  
  Bax
2.

All are true statements about arterial thrombi, EXCEPT:
- A.
  
  They are dark red in color with a higher concentration of red cells.
- B.
  
  Formed in areas of active blood flow.
- C.
  
  Forms layers called Lines of Zahn.
- D.
  
  May eventually liquefy & disappear.
3.

Systemic Lupus Erythematosus is what type of Immune Dysfunction?
- A.
  
  Type IV --- Cell Mediated Hypersensitivity
- B.
  
  Type III --- Immune Complex Hypersensitivity
- C.
  
  Type II --- Cytotoxic Hypersensitivity
- D.
  
  Type I --- Anaphylactic Hypersensitivity
4.

All true statements of Mitral Valve Diseases, EXCEPT:
- A.
  
  The mitral valve is the valve most commonly affected in carcinoid syndrome.
- B.
  
  Mitral valve prolapse is the most frequent valvular lesion.
- C.
  
  Upon ausculatation, a systolic murmur with midsystolic click can be heard in patients with MVP.
- D.
  
  Mitral stenosis & insufficiency is most usually due to rheumatic heart diseases.
5.

Which statement best describes Silicosis?
- A.
  
  It is caused by inhalation of carbon dust & causes no harm.
- B.
  
  It is marked by coal macules surrounding the bronchioles.
- C.
  
  It predisposes a person to have bronchogenic carcinoma or mesothelioma.
- D.
  
  It is associated with increased susceptibility with tuberculosis.
6.

This is also known as giant hypertrophic gastritis.
- A.
  
  Menetrier's Disease
- B.
  
  Meniere's Disease
- C.
  
  Loeffler's Eosinophilia
- D.
  
  Whipple's Disease
7.

Correct statements about liver cirrhosis, EXCEPT:
- A.
  
  Alcoholic cirrhosis is otherwise known as Laennec's cirrhosis.
- B.
  
  Primary biliary cirrhosis is due to long-standing extrahepatic biliary obstruction.
- C.
  
  There is decreased ceruloplasmin in cirrhosis caused by Wilson's disease.
- D.
  
  Postnecrotic cirrhosis is usually due to a previous hepatitis B infection.
8.

All are true statements about benign prostatic hyperplasia, EXCEPT:
- A.
  
  There is a rubbery, nodular enlargement of the gland especially in the periurethral and peripheral zones.
- B.
  
  It is the most common cause of urinary tract obstruction in males.
- C.
  
  It has no relation to prostatic cancer, but the two can coexist.
- D.
  
  May be caused by an age-related increase in estrogen.
9.

What is the most common site for endometriosis?
- A.
  
  Rectum
- B.
  
  Round ligament
- C.
  
  Fallopian tube
- D.
  
  Ovary
10.

True of Hypothyroidism, EXCEPT:
- A.
  
  Myxedema is more common in men than women.
- B.
  
  TSH-receptor blocking antibodies are positive in Hashimoto's thyroiditis.
- C.
  
  The patient may have hair loss, coarse & brittle hair and scant axillary/pubic hair.
- D.
  
  Cretinism may be due to transplacental transfer of antithyroid antibodies.
11.

This condition is characterized by multiple vascular tumors and cysts that are widely scattered througout the organ systems.
- A.
  
  Port-wine stain
- B.
  
  Granuloma pyogenicum
- C.
  
  Sturge-Weber Syndrome
- D.
  
  Von Hippel Lindau disease
12.

This condition is characterized by a triad of precocious puberty, fibrous dysplasia and cafe-au-lait spots on skin, occuring often in young girls.
- A.
  
  Osteogenesis imperfecta
- B.
  
  McCune-Albright Syndrome
- C.
  
  Legg-Calve-Perthes Disease
- D.
  
  Osgood-Schlatter Disease
13.

Etiological agent for an encephalitis that is characterized by degeneration and necrosis of anterior horn cells of the spinal cord.
- A.
  
  Cytomegalovirus
- B.
  
  Polio virus
- C.
  
  Arboviruses (Western/Eastern Equine)
- D.
  
  Rabies
14.

Which one of the following renal tubular changes revealed by kidney biopsy repersents irreversible cellular injury?
- A.
  
  Fatty change
- B.
  
  Nuclear pyknosis
- C.
  
  Formation of myelin figures
- D.
  
  Swelling of organelles
15.

An autosmal recessive defect in neutrophils characterized by albinism, cranial & peripheral neuropathy.
- A.
  
  Chronic granulomatous disease
- B.
  
  Leukocyte-adhesion deficiency type 1 & 2
- C.
  
  Myeloperoxidase deficiency
- D.
  
  Chediak-Higashi Syndrome
16.

A genetic condition characterized by deficiency in sphingomyelinase causing resultant accumulation of sphingomyelin.
- A.
  
  Gaucher Disease
- B.
  
  Hurler Disease
- C.
  
  Niemann-Pick Disease
- D.
  
  Von Gierke Disease
17.

True of Wegener's granulomatosis, EXCEPT:
- A.
  
  Characterized by necrotizing granulomatous vasculitis of the medium to large-sized vessels.
- B.
  
  Commonly affects the respiratory tract & kidneys.
- C.
  
  Associated with C-ANCAs.
- D.
  
  There is fibrinoid necrosis, early infiltration of neutrophils and fibrosis.
18.

All are true statements about disorders of primary hemostasis, EXCEPT:
- A.
  
  They are mainly defects of platelet plug formation.
- B.
  
  Characterized by bleeding from small capillaries resulting in mucocutaneous bleeding.
- C.
  
  Often marked by prolonged bleeding time and normal APTT and PT.
- D.
  
  Von Willebrand's disease is a defect in platelet aggregation.
19.

Fungi that causes lung infection but may eventually involve the CNS. Its characteristic encapsulated appearance can be seen via India ink preparations.
- A.
  
  Cryptococcus neoformans
- B.
  
  Actinomyces
- C.
  
  Histoplasma capsulatum
- D.
  
  Coccidioides immitis
20.

This is characterized by multiple adenomatous polyps with tumors of the central nervous system.
- A.
  
  Gardner syndrome
- B.
  
  Turcot syndrome
- C.
  
  Peutz-Jegher syndrome
- D.
  
  Familial Adenomatous Polyposis
21.

True of Renal Cell Carcinoma, EXCEPT:
- A.
  
  It is the most common renal malignancy and is more common in men.
- B.
  
  It is characterized by polygonal clear cells and notorious for hematogenous dissemination.
- C.
  
  A triad of flank pain, hematuria and palpable mass. The most common of the 3 is flank pain.
- D.
  
  There is secondary polycythemia due to increased erythropoietin production.
22.

What is Peyronie disease?
- A.
  
  It is an anomaly wherein the urethral meatus opens on the ventral face of the penis.
- B.
  
  It is an abnormally tight foreskin that is difficult or impossible to retract over the glans penis.
- C.
  
  It is the subcutaneous fibrosis of the dorsum of the penis.
- D.
  
  Inflammation of the glans penis.
23.

True of a Hydatidiform mole, EXCEPT:
- A.
  
  It grossly resembles a bunch of grapes. Microscopically, the villi are hydropic.
- B.
  
  Marked by a significant increase in B-HCG and rapid increase in uterine size.
- C.
  
  An embryo is present in a complete mole.
- D.
  
  There are 69 chromosomes in a partial mole.
24.

True of tumors of the breast, EXCEPT:
- A.
  
  Paget's Disease is a large, bulky mass with variable malignancy with ulceration of overlying skin.
- B.
  
  Fibroadenoma is the most common breast tumor in women younger than 25 years old.
- C.
  
  Intraductal papilloma is most commonly manifested as serous or bloody discharge.
- D.
  
  Medullary carcinoma of the breast is characterized by scanty stroma, fleshy consistency and lymphocytic infiltrate.
25.

This characterized by presence of pheochromocytoma, medullary carcinoma of the thyroid, and hyperparathyroidism. It is linked to mutations to the ret oncogene.
- A.
  
  Wermer Syndrome
- B.
  
  Sipple Syndrome
- C.
  
  Men IIb
- D.
  
  Zollinger-Ellison Syndrome