USMLE Full Length Exam 1 assesses a range of medical knowledge through scenarios involving patient symptoms, diagnosis, and treatment. It tests understanding of pathophysiology, clinical medicine, and therapeutic interventions.
The third and fourth branchial (pharyngeal) arches have hypertrophied
The thymus has developed ectopically
The thymus has hypertrophied
The thyroid has failed to migrate caudally
The thyroid has migrated too far rostrally
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Blue dome cysts and some atypical epithelial hyperplasia
Cells in a single fi le formation
Fibrosing stroma around normal-looking glands
Large cells with clear “halos”
Multicentric lobes with lymphocytic infi ltrate
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A
B
C
D
E
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Age-related increase in estradiol with possible prostate dihydrotestosterone sensitization
Autosomal recessive dysfunction of a chloride ion channel
Failure of testicles to descend into the scrotum
Familial disease causing early atherosclerosis leading to erectile dysfunction
Lack of dynein ATPase arms in microtubules of cilia
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Allele-specifi c oligonucleotide probe
Enzyme-linked immunosorbent assay
Northern blot
Polymerase chain reaction
Sequencing
Southern blot
Western blot
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Acidifi cation of the urine traps ionized molecules in the tubule
Acidifi cation of the urine traps nonionized molecules in the tubule
Acidifi cation of urine will increase the glomerular fi ltration rate
Alkalinization of the urine traps ionized molecules in the tubule
Alkalinization of the urine traps nonionized molecules in the tubule
Alkalinization of urine will increase the glomerular fi ltration rate
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Bicarbonate
Calcium
Chloride
Potassium
Sodium
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Bartonella henselae
Borrelia burgdorferi
Eikenella corrodens
Francisella tularensis
Pasteurella multocida
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Herpes simplex virus type 2
Measles virus
Mumps virus
Neisseria meningitidis
Rubella virus
Treponema pallidum
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Decreased platelet count
Decreased von Willebrand factor
Defect in hydroxylation of collagen residues
Mutation of dystrophin gene
Mutation of spectrin
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Coronary artery disease
Dilated cardiomyopathy
Myxoma
Rhabdomyoma
Transposition of the great vessels
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Adult-onset asthma
Amiodarone
Diltiazem
Sotalol
Tobacco
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Blood transfusion
Chemotherapy
Folic acid supplementation
Iron chelation therapy
Iron supplementation
Splenectomy
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Parathyroid adenoma
Parathyroid insuffi ciency
Renal failure
Underlying malignancy
Vitamin D intoxication
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Enterococcus faecalis
Staphylococcus epidermidis
Streptococcus agalactiae
Streptococcus pneumoniae
Streptococcus sanguis
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Budd-Chiari syndrome
Congestive heart failure
Polymyalgia rheumatica
Portal vein thrombosis
Veno-occlusive disease
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Myocardial infarction
Pericarditis
Prinzmetal’s angina
Stable angina
Unstable angina
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A build-up of unmeasured anions due to hepatic metabolism of alcohol
Electrolyte imbalance due to diuretic use
Hyperventilation secondary to pain and anxiety
Hypoventilation due to the respiratory depression caused by alcohol ingestion
Vomiting due to alcohol toxicity
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Begin taking a bile acid resin
Begin taking a statin
Begin taking low-dose oral contraceptives
Exercise 30 minutes three times per week
Quit smoking
Reduce alcohol consumption to one or two glasses of red wine per week
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IgA nephropathy
Interstitial nephritis due to medications
Poststreptococcal glomerulonephritis
Rapidly progressive glomerulonephritis
Systemic lupus erythematosus
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Ask her on a date
Continue the visit as normal
Refer her to another doctor
Refer her to another doctor, then ask her on a date
Return to the room with a chaperon and conduct the visit as normal
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Blood alcohol level
Blood, urine, and sputum cultures
CT of the head
Electroencephalography
Urine toxicology screen
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Adipocytes
Cortical neurons
Erythrocytes
Hepatocytes
Pancreatic β cells
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Asperger’s syndrome
Autistic disorder
Childhood disintegrative disorder
Expressive language disorder
Rett’s disorder
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Acute acalculous cholecystitis
Acute calculous cholecystitis
Acute pancreatitis
Carcinoma of the pancreas
Cholesterolosis
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Anticentromere antibodies
Anti-endothelial cell antibodies
Antihistone antibodies
Anti-IgG antibodies
Antinuclear antibodies
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An increased partial oxygen pressure at 50% saturation on the hemoglobin-oxygen dissociation curve
Decreased pulmonary vascular resistance
Decreased RBC 2,3-diphosphoglycerate concentration
Increased arterial partial oxygen pressure
Right ventricular atrophy
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Aorticopulmonary septum
Ductus arteriosus
Ductus venosus
Foramen ovale
Interventricular septum
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Familial adenomatous polyposis
Gardner syndrome
Hereditary nonpolyposis colorectal carcinoma
Tuberous sclerosis
Turcot syndrome
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Anterior bladder wall rupture
Penile urethra rupture
Superior bladder wall rupture
Urethral rupture above the urogenital diaphragm
Urethral rupture below the urogenital diaphragm
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Cancer of a visceral organ
Osteoarthritis
Psoriasis
Secondary syphilis
Zenker’s diverticulum
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Acrolein for hemorrhagic cystitis
Acrolein for myelosuppression
Acrolein for nausea and vomiting
N-acetylcysteine for hemorrhagic cystitis
N-acetylcysteine for myelosuppression
N-acetylcysteine for nausea and vomiting
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Diffuse epithelial foot process fusion
Immune complex deposits
Split basement membrane
Wire-loop appearance
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Echocardiogram
Hemicraniectomy
Heparin
Insulin
Tissue plasminogen activator
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Clozapine
Imipramine
Lithium
Phenytoin
Sumatriptan
Valproic acid
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80%
85%
89%
90%
95%
99%
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Cysteine
Lysine
Methionine
Tryptophan
Tyrosine
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Glucosylceramide
Histidine
Phenylalanine
Sphingomyelin
Tyrosine
Valine
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Decrease in blood pressure
Decrease in heart rate
Increase in blood pressure
Increase in respiratory rate
No changes in vital signs
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Adductor pollicis
Dorsal interossei
Lumbricals (3 and 4)
Opponens digiti minimi
Opponens pollicis
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Cooper’s ligament
Femoral canal
Femoral nerve
Obturator nerve
Tunica vaginalis
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Azathioprine
Cisplatin
Doxorubicin
Paclitaxel
β-Interferon
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Autoimmune hemolytic anemia
Crigler-Najjar syndrome type I
Gilbert’s disease
Hepatitis C
Oral contraceptive-associated cholestasis
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Bowman’s space hydrostatic pressure will be decreased
Bowman’s space hydrostatic pressure will be increased
Bowman’s space oncotic pressure will be decreased
Glomerular capillary hydrostatic pressure will be increased
Glomerular capillary oncotic pressure will be decreased
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Escherichia coli
Pseudomonas aeruginosa
Salmonella species
Shigella species
Vibrio cholerae
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Angiosarcoma
Basal cell carcinoma
Colorectal carcinoma
Melanoma
Prostate cancer
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Gastroesophageal junction
Ligament of Treitz
Pancreaticoduodenal junction
Rectosigmoid junction
Splenic flexure
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