Hardest Trivia Questions Quiz On USMLE

100 Questions | Total Attempts: 143

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Hardest Trivia Questions Quiz On USMLE

What we have here is the hardest trivia questions quiz on USMLE. Medical practitioners are selfless and do everything possible to save the life of their patients with their underlying oath being that they cannot harm. For you to prove that you understand what is expected of you as a medical practitioner by your patients, you will need to pass the medical licensing exams.


Questions and Answers
  • 1. 
    • A. 

      Diameter of pulmonary vessels

    • B. 

      Erythropoietin production

    • C. 

      Mitochondrial density in a muscle biopsy

    • D. 

      Renal bicarbonate (HCO3-) excretion

    • E. 

      Respiratory rate

  • 2. 
    A woman presents to a dermatologist because she has lost almost all the hair on her body, including scalp hair, eyebrows, eyelashes, armpit, and groin hair, and the fine hairs on her body and extremities. Does she most likely have a variant of which of the following?
    • A. 

      Alopecia areata

    • B. 

      Androgenic alopecia

    • C. 

      Chronic cutaneous lupus erythematosus

    • D. 

      Lichen planopilaris

    • E. 

      Trichotillomania

  • 3. 
    The greater omentum is derived from which of the following embryonic structures?
    • A. 

      Dorsal mesoduodenum

    • B. 

      Dorsal mesogastrium

    • C. 

      Pericardioperitoneal canal

    • D. 

      Pleuropericardial membranes

    • E. 

      Ventral mesentery

  • 4. 
    A 34-year-old woman has prescribed an antidepressant, which she has taken for the past 3 months. She is on no other medications and is in generally good health. After attending a party, at which she consumed wine and cheese, she is rushed to the emergency room with tachycardia, headache, and blood pressure of 200/100. Which antidepressant is she most likely taking?
    • A. 

      Amitriptyline

    • B. 

      Fluoxetine

    • C. 

      Phenelzine

    • D. 

      Sertraline

    • E. 

      Trazodone

  • 5. 
    Which of the following hormones is secreted by anterior pituitary cells that stain with acidic dyes?
    • A. 

      ACTH

    • B. 

      FSH

    • C. 

      LH

    • D. 

      Prolactin

    • E. 

      TSH

  • 6. 
    A 23-year-old male graduate student gets into a serious argument with one of his college professors, making a physical threat to the professor, and necessitating a call to campus security. The argument was precipitated by an incident between the professor and the student's girlfriend; when the professor corrected the student's girlfriend in class, the student felt the professor was verbally abusive. Which of the following is the most likely diagnosis?
    • A. 

      Dependent personality disorder

    • B. 

      Histrionic personality disorder

    • C. 

      Narcissistic personality disorder

    • D. 

      Paranoid personality disorder

    • E. 

      Passive aggressive personality disorder

  • 7. 
    Which of the following would shift the oxygen-hemoglobin dissociation curve to the right?
    • A. 

      Carbon monoxide poisoning

    • B. 

      Decreased PCO2

    • C. 

      Decreased pH

    • D. 

      Decreased temperature

    • E. 

      Decreased 2,3-DPG

  • 8. 
    The wife of a 48-year-old male patient brings him to the emergency room and says that his memory has progressively gotten worse over the last several years. She also says his personality has been changing. The physician notes abnormal writhing movements of the man's limbs and hyperreactive reflexes. MRI reveals a loss of volume in the neostriatum and cortex. This disease is inherited via an
    • A. 

      Autosomal dominant trait

    • B. 

      Autosomal recessive trait

    • C. 

      X-linked dominant trait

    • D. 

      X-linked recessive trait

  • 9. 
    A man presents to a dermatologist because of a severe mucocutaneous rash that involves most of his body, including his palms and soles. Questioning reveals that he is a merchant marine who several months previously had an encounter with a prostitute in Southeast Asia. Which of the following is the most likely causative agent of this rash?
    • A. 

      Herpes simplex I

    • B. 

      Herpes simplex II

    • C. 

      HIV

    • D. 

      Neisseria gonorrhoeae

    • E. 

      Treponema pallidum

  • 10. 
    A patient with familial hypercholesterolemia undergoes a detailed serum lipid and lipoprotein analysis. Studies demonstrate elevated cholesterol in the form of increased LDL without elevation of other lipids. This patient's hyperlipidemia is best classified as which of the following types?
    • A. 

      Type 1

    • B. 

      Type 2a

    • C. 

      Type 2b

    • D. 

      Type 3

    • E. 

      Type 5

  • 11. 
    • A. 

      Adrenocorticotrophic hormone (ACTH)

    • B. 

      Epinephrine

    • C. 

      Oxytocin

    • D. 

      Prolactin

    • E. 

      Thyroid stimulating hormone (TSH)

  • 12. 
    Which of the following organisms is the most common cause of community-acquired pneumonia?
    • A. 

      Chlamydia pneumoniae

    • B. 

      Haemophilus influenzae

    • C. 

      Mycoplasma pneumoniae

    • D. 

      Staphylococcus aureus

    • E. 

      Streptococcus pneumoniae

  • 13. 
    A 54-year-old male with acute lymphocytic leukemia develops a blast crisis. He is treated with intensive systemic chemotherapy. Following treatment, the patient will be at increased risk for the development of
    • A. 

      Bile pigment gallstones

    • B. 

      Cholesterol gallstones

    • C. 

      Cystine kidney stones

    • D. 

      Struvite kidney stones

    • E. 

      Uric acid kidney stones

  • 14. 
    A 65-year-old man with mild heart failure is treated with a loop diuretic . A few days later the man complains of muscle weakness. Laboratory results are shown below. Arterial PCO2: 48 mm Hg Arterial pH: 7.49 Plasma HCO3-: 35 mEq/L Which of the following is most likely decreased in this man?
    • A. 

      Plasma aldosterone

    • B. 

      Plasma potassium

    • C. 

      Potassium excretion

    • D. 

      Renin secretion

    • E. 

      Sodium excretion

  • 15. 
    A 27-year-old white male presents with a 3-week history of several swollen and painful toes and knees. He has a past history of conjunctivitis. He also describes some low back stiffness that is more severe in the morning. Which of the following is the most likely diagnosis?
    • A. 

      Gout

    • B. 

      Lyme disease

    • C. 

      Reiter's syndrome

    • D. 

      Rheumatoid arthritis

    • E. 

      Septic arthritis

  • 16. 
    A 37-year-old woman who was diagnosed with AIDS 3 years earlier is unable to work, is physically debilitated, and requests her physician to provide her with medications with which to take her own life. The most common emotional disorder that results in such requests by patients is
    • A. 

      Bipolar I disorder, manic type

    • B. 

      Borderline personality disorder

    • C. 

      Factitious disorder

    • D. 

      Major depressive disorder

    • E. 

      Schizophrenic disorder

  • 17. 
    A 25-year-old man presents with a chief complaint of persistent, high-pitched ringing noises in his ears. Questioning reveals that he has also been losing his balance lately. CT of the head demonstrates bilateral tumors involving the vestibulocochlear nerve. Which of the following chromosomes contains the tumor suppressor gene most likely to be involved in this case?
    • A. 

      5q

    • B. 

      13q

    • C. 

      17q

    • D. 

      18q

    • E. 

      22q

  • 18. 
    An autopsy is performed on a man who suddenly began vomiting voluminous quantities of blood and exsanguinated. Which of the following organisms is most likely implicated in the pathogenesis of this disease?
    • A. 

      Cryptosporidium parvum

    • B. 

      Entamoeba histolytica

    • C. 

      Escherichia coli

    • D. 

      Helicobacter pylori

    • E. 

      Mycobacterium tuberculosis

  • 19. 
    During embryological development, hematopoiesis occurs in different organs at different times. Which of the following are the correct organs, in the correct sequence, at which hematopoiesis occurs embryologically?
    • A. 

      Amnion, yolk sac, placenta, bone marrow

    • B. 

      Placenta, liver and spleen, yolk sac, bone marrow

    • C. 

      Placenta, spleen and lymphatic organs, bone marrow

    • D. 

      Yolk sac, bone marrow, liver and spleen

    • E. 

      Yolk sac, liver, spleen and lymphatic organs, bone marrow

  • 20. 
    A 27-year-old male is brought into the emergency room by the police, who found him walking aimlessly, shouting the names of former Presidents. Urine toxicology is negative, and the man appears to be oriented with respect to person, place, and time. He has had five similar admissions over the past year. Attempts to interview the patient are fruitless, as he seems easily derailed from his train of thought. A phone call to a friend listed in the chart provides the additional information that the man is homeless, and unable to care for himself. This patient is exhibiting the signs and symptoms of
    • A. 

      Schizoaffective disorder

    • B. 

      Schizoid personality disorder

    • C. 

      Schizophrenia

    • D. 

      Schizophreniform disorder

    • E. 

      Schizotypal personality disorder

  • 21. 
    Molecular genetic studies are performed on a family with known familial hypercholesterolemia. In this particular family, the defect in the LDL receptor gene involves a messenger mutation near the 11th exon, in the region of homology with epidermal growth factor receptor precursor. A defect at this site would be most likely to produce which of the following effects?
    • A. 

      Decreased transcription of LDL receptor gene

    • B. 

      Poor internalization of LDL bound to LDL receptor

    • C. 

      Poor retention of the LDL receptor in the membrane

    • D. 

      Reduced binding of LDL

    • E. 

      Trapping of the LDL receptor in the endoplasmic reticulum

  • 22. 
    A 27-year-old woman is giving birth. During the birth, the placental membranes tear and amniotic fluid is expressed into a lacerated cervical vein. Which of the following is the woman most likely to experience immediately following this event?
    • A. 

      Hemiplegia

    • B. 

      Placental abruption

    • C. 

      Renal failure

    • D. 

      Respiratory distress

    • E. 

      Splinter hemorrhages

  • 23. 
    A 30-year-old pregnant woman complains to her physician of feeling very tired during her pregnancy. A complete blood count with differential reveals a hematocrit of 30%, with hypersegmented neutrophils and large, hypochromic red cells. Deficiency of which of the following would be most likely to produce these findings?
    • A. 

      Ascorbic acid

    • B. 

      Calcium

    • C. 

      Copper

    • D. 

      Folate

    • E. 

      Iron

  • 24. 
    An otherwise healthy 3-year-old child is brought to the pediatrician with umbilicated, flesh-colored papules on his trunk. This condition is related to infection with which of the following viruses?
    • A. 

      Cytomegalovirus

    • B. 

      Herpesvirus 6

    • C. 

      Parvovirus

    • D. 

      Poxvirus

    • E. 

      Variola

  • 25. 
    Which of the following renal structures is most medially located?
    • A. 

      Major calyx

    • B. 

      Minor calyx

    • C. 

      Renal cortex

    • D. 

      Renal pelvis

    • E. 

      Renal pyramid