Reproductive Drugs
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This quiz includes material from lecture and speaker notes as well as questions from ATI and the posted Reproduction Powerpoint questions.
- 1.
- A.
More effective in woman who smoke or are older than 35
- B.
Can be taken while breastfeeding
- C.
Used for endometriosis
- D.
Can be taken for hyperlipidemia and if one is diabetic
- E.
Can be taken for migraine headaches if using estrogen only
- 2.Ovulation Suppressants - Oral Contraceptives of Estrogen-Progestin Combination suppress pituitary release of FSH and LH which.....
- A.
Is needed to suppress growth of a follicle in the ovary, inhibiting ovulation.
- B.
The cervical mucus is thinned by progestin, making it hostile to sperm.
- C.
Changes the environment of endometrium, making it less favorable for implantation.
- D.
Is needed to mature a follicle in ovary, inhibiting ovulation.
- E.
The cervical mucus is thickened by progestin, making it hostile to sperm.
- 3.True or False. Estrogen - Progestin is a combination of ethinyl estrodiol and synthetic progesterone.
- A.
True
- B.
False
- 4.Estrogen- Progestin Combination. Mark all that apply to Monophasic bc.
- A.
Estrogen and Progesterone varies throughout cycle
- B.
Estrogen and progestin have a fixed ratio throughout menstrual cycle
- C.
Estrogen is fixed and progesterone varies
- 5.Estrogen-Progestin Combination. Which of the following are Monophasic Birth Control?
- A.
Norinyl
- B.
Lo/Ovral
- C.
Orth-Novum
- D.
Ortho Tri-Cyclen
- E.
Loestrin
- 6.Estrogen - Progestin Combination. What is true of Biphasic BC?
- A.
Estrogen and progesterone varies throughout cycle
- B.
Is a fixed ratio of estrogen to progestin throughout menstrual cycle
- C.
Estrogen is fixed throughout and progesterone varies
- 7.Estrogen - Progesterone Combination. What is true of Triphasic bc?
- A.
Estrogen is fixed throughout and progesterone varies
- B.
Is a fixed ratio of estrogen to progestin throughout menstrual cycle
- C.
Estrogen and progesterone varies throughout cycle
- 8.Estrogen - Progestin Combination. What Drugs are Biphasic bc?
- A.
Ortho-Novum
- B.
Ortho Tri-cyclen
- C.
Norinyl
- D.
Lo/Ovral
- E.
Loestrin
- 9.Estrogen - Progestin Combination. What Drugs are Triphasic bc?
- A.
Lo/Ovral
- B.
Ortho-Novum
- C.
Norinyl
- D.
Ortho Tri-cyclen
- E.
Loestrin
- 10.Progestin only birth control or the "mini pill" ....
- A.
Suppresses activity of pituitary
- B.
Alters the cervical mucus making thicker
- C.
Alters the pH of the cervical mucus
- D.
Does not suppress activity of the pituitary.
- 11.Progestin only "Mini pills" (mark all that apply) Remember if you are more than 3 hours late taking these drugs, you will need to use a back-up method.
- A.
Mirena
- B.
Ovrette
- C.
Norinyl
- D.
Micronor
- E.
Nor-ZD
- 12.Another form of Progestin only BC is Depo-Provera (medroxyprogesterone acetate). Depo...
- A.
Side effects include: bloating, decreased libido, hair loss, weight loss, and depression.
- B.
Is a long term injectable progestin that is injected every 3 mo
- C.
Can not be injected post-delivery and during breastfeeding
- D.
Suppresses ovulation & changes pH of vaginal mucosa
- E.
Can cause irregular menstruation and spotting initially
- 13.Choose all of the side effects that are related to estrogen.
- A.
Fluid Retention/ Edema/ Bloating
- B.
Weight gain/ Breast enlargement & tenderness
- C.
N/V with Headache
- D.
Hypertension / Dizziness
- E.
Leg cramps
- 14.Choose all of the side effects that are related to progestin.
- A.
Increased appetite with weight gain
- B.
Amenorrhea after cessation of use
- C.
Depression/ Excess hair growth/ decreased breast size
- D.
Oily skin & scalp / acne
- E.
Can cause epilepsy
- 15.A client who is her 30th week of gestation is determined to have postfetal demise. She asks the nurse why she is being given a prostaglandin gel (PG) suppository at this time. The best response by the nurse is:
- A.
“PG suppositories help relieve the pain you will experience when the baby is delivered."
- B.
“PG suppositories will allow you to relax and decrease your anxiety.”
- C.
“PG suppositories cause labor to start”
- D.
“PG suppositories prevent postpartum infections in cases like yours.”
- 16.Prostaglandin gel is used to induce labor in cases in which there is second or third trimester fetal demise. They stimulate smooth muscle and cause the uterine to contract. Prostaglandin gel has no analgesic, antianxiety nor antibiotic effects.
- A.
True
- B.
False
- 17.A Client who has been in labor for 6 hours is still having irregular and weak contractions. When oxytocin (Pitocin) is started, the client tells the nurse she is afraid of this medication because when her sister had it, her baby died. The best response by the nurse would be:
- A.
“I’m sure you’ll be fine. Your sister’s situation was a lot different from yours.”
- B.
“You seem to be anxious. Tell me more about your fears.”
- C.
“Complications are rare, and we are prepared to handle any development.”
- D.
“This is a very dangerous medication, but we’ll keep a close watch on your condition.”
- 18.A pregnancy client who is gravida 3, para 2, is admitted with severe pregnancy-induced hypertension. Her physician wants to start IV Magnesium Sulfate at 2g/h. What are the initial side effects the nurse should explain to the client?
- A.
Hypotension, decreased respirations
- B.
Hypofelxia and flaccid paralysis
- C.
Flushing, sweating, irritability
- D.
Vomiting and Diarrhea
- 19.A client who is at 27 weeks gestation with spontaneously ruptured membranes and no contractions is admitted to the preterm labor unit. Which of the following medications will the nurse most likely administer to promote fetal lung maturation.
- A.
Betamethasone
- B.
Prostaglandin gel
- C.
Magnesium sulfate
- D.
Ritodrine
- 20.A postpartum client who has 40 U of oxytocin (Pitocin) in her IV bag after the placenta is delivered continues to hemorrage even after unterine massage. Her vital signs are pulse 120, BP 90/50, respirations 26. The nurse anticipates the physician will order which of the following to stop the atony and hemorrhage?
- A.
Ibuprofen
- B.
Prostaglandin Gel
- C.
Ephedrine
- D.
Methergine
- 21.Terbutaline (brethine) is indicated in preterm labor to
- A.
Stop uterine contractions
- B.
Prevent bleeding
- C.
Promote placental blood flow
- D.
Increase prostaglandin production
- 22.Factors that preclude the use of birth control pills include:
- A.
Pregnancy
- B.
Thromboembolic disorders (hypercoagulability)
- C.
Cancer (stimulate tumor growth)
- D.
Hypertension (increased angiotensin and retention of sodium and water)
- E.
Women over 30 who smoke (decreased estrogenic effect and increased platelet aggregation)
- 23.A college student comes into the health clinic to renew her prescription for oral contraceptives. While she is there, she reports a sore throat and fever for 2 days. A throat culture for streptococcus is positive and she is placed on ampicillin and her oral contraceptives prescription is refilled. The nurse should tell the patient what about the birth control....
- A.
Tell the patient to drink plenty of water.
- B.
Tell the patient to take ampicillin 500mg four times a day for 10 days.
- C.
Tell the patient that taking the ampicillin and oral contraceptive together will decrease the effectivieness.
- D.
Tell the patient to get plenty of rest.
- 24.A nurse is providing teaching to a client receiving tamoxifen (Novadex) for breast cancer prevention. Which of the following statements indicates the client has understood the teaching?
- A.
I may experience hot flashes
- B.
I will be so excited when I finally get pregnant
- C.
I should be sure to drink plenty of milk
- D.
I will eat a diet high in fat to prevent weight loss
- 25.Testosterone enanthate (Delatestryl) is used for?
- A.
Breast cancer prevention
- B.
Treatment for erectile dysfunction
- C.
Contraindicated for athletic performance enhancement
- D.
Treatment of endometriosis
- 26.Conjugated equine estrogens (Premarin) is used for
- A.
Breast cancer prevention and treatment
- B.
Contraception
- C.
Relief of postmenopausal symptoms
- D.
Dysfunctional uterine bleeding due to hormonal balance
- E.
Treatment of endometriosis
- 27.Medroxyprogesterone acetate (Provera) is used for
- A.
Relief of postmenopausal symptoms
- B.
Treatment of endometriosis
- C.
Dysfunctional uterine bleeding due to hormonal balance
- D.
Breast cancer prevention and treatment
- E.
Contraception
- 28.Ovcon 35 is used for?
- A.
Breast cancer prevention and treatment
- B.
Treatment of endometriosis
- C.
Relief of postmenopausal symptoms
- D.
Contraception
- E.
Dysfunctional uterine bleeding due to hormonal balance
- 29.Leuprolide (Lupron) is used for?
- A.
Treatment of endometriosis
- B.
Dysfunctional uterine bleeding due to hormonal balance
- C.
Breast cancer prevention and treatment
- D.
Contraception
- E.
Relief of postmenopausal symptoms
- 30.Tamoxifen (Nolvadex) is used for?
- A.
Relief of postmenopausal symptoms
- B.
Dysfunctional uterine bleeding due to hormonal balance
- C.
Treatment of endometriosis
- D.
Contraception
- E.
Breast cancer prevention and treatment
- 31.Sildenafil (Viagra) is used for?
- A.
Treatment of endometriosis
- B.
Treatment of erectile dysfunction
- C.
Contraindicated for athletic performance
- D.
Breast cancer prevention and treatment
- 32.What are the uses of estrogen?
- A.
Used for menstrual disturbances and menopause
- B.
Acne in females
- C.
Lactation suppression
- D.
Prostate CA treatment
- E.
Osteoporosis
- 33.True or False. Estrogen may be used to maintain bone mass in postmenopausal clients. Estrogen must be d/ced if client shows signs and symptoms of deep vein thrombosis or cardiac complications.
- A.
True
- B.
False
- 34.Steroidal Estrogen include:
- A.
Premarin
- B.
DES
- C.
OGEN
- D.
TACE
- E.
Estrace
- 35.Uses of Progestin include:
- A.
Used to decrease spontaneous contractions
- B.
Helps develop mammory duct during pregnancy
- C.
Helps prepare the uterus and maintain pregnancy
- D.
Helps maintain functional uterine bleeding caused by hormonal imbalance, bibroid, or uterine cancer.
- E.
Works as a anti-contraceptive
- 36.Severe Side Effects of Progestin.
- A.
Superficial and DVT
- B.
Pulmonary Embolism (PE)
- C.
Cerebrovascular accident (stroke)
- D.
Myocardial infarction (MI)
- E.
Acceleration of preexisting but non-diagnosed breast tumor
- 37.As a nurse what nursing interventions should you consider?
- A.
Teach: proper administration
- B.
Teach: How to monitor menstrual cycle
- C.
Promote: Smoking cessation
- D.
Encourage: breast cancer screenings
- E.
Teach: Signs and symptoms of a blood clot
- 38.What drugs are Ovulation Stimulants?
- A.
Micronor
- B.
Clomid
- C.
Lupron
- D.
Ovrette
- E.
Parlodel
- 39.If you are on (strict compliance) Ovulation Stimulants you may experience some of these side effects:multiple pregnancies, blurred vision, dvt, and what else?
- A.
Dizzy, HA, flushed, depression, restlessness, anxiety
- B.
Tachycardia
- C.
Constipation/n/pain/anorexia
- D.
Bradycardia
- E.
Diarrhea/n/v
- 40.True or False? Endometriosis is a condition in which the tissue that normally lines the uterus (endometrium) grows in other areas of the body (pelvic cavity), causing pain, irregular bleeding, and possible infertility.
- A.
True
- B.
False
- 41.Endometriosis. GnRH stands for Gonadotrophin Releasing Hormone. The body normally makes GnRH in a small gland in the brain (the pituitary) and it is this hormone that stimulates the ovary to develop eggs and produce oestrogen, leading to the normal menstrual cycle. If you give GnRH agonists, this floods the system and confuses the delicately controlled balance, leading to a complete block of egg development, oestrogen production and menstrual cycle. It effectively makes you 'menopausal' for the short time that you use the treatment and without the oestrogen stimulation, endometriosis shrinks down and becomes inactive. Which drugs are considered GnRH agonists?
- A.
Lupron
- B.
Danazol (Danocrine)
- C.
Leuprolide acetate (Lupron Depot)
- D.
Clomid
- E.
Nafarelin acetate (synarel)
- 42.What is true regarding Menopause?
- A.
Can occur in you late 30s
- B.
Includes increased menstration
- C.
Includes decreased menstration
- D.
Hotflashes
- E.
Vaginal dryness
- 43.True or False? During Postmenopause the ovaries lose ability to secrete estrogen. Estrone is then formed in the Brain, Liver, Kidney and Adipose tissue and becomes the main source of estrogen.
- A.
True
- B.
False
- 44.Hormone Replacement Therapy (HRT) is
- A.
Associated with increased risk of breast cancer, thromboembolism, CAD, & stroke
- B.
Is used at lowest dose for less than five years
- C.
Is a combination of estrogen and progestin
- D.
Is contraindicated with cancer, thromboembolic events, liver disease, gallbladder disease, pancreatic disease, HTN, and endometriosis
- 45.To help prevent osteoporosis one should take ? mg of calcium daily with vitamin D.
- A.
1800
- B.
2100
- C.
1200
- D.
2200
- E.
2000
- 46.Uterine Motility Drugs involve three groups: Uterine stimulants, Prostaglandins/Ergot Alkaloids, and Tocolytics (preterm labor). What is Oxytocin (Pitocin, Syntocinon) used for?
- A.
Initial induction of labor
- B.
Induce abortion
- C.
Promote suppression of letdown of breast milk (nasal spray)
- D.
Control uterine bleeding
- E.
Increases the force and frequency of contractions
- 47.Oxytocin makes contractions more excessive and strong which coincides with these side effects:
- A.
Increased blood loss
- B.
Uterine rupture
- C.
Pelvic hematoma
- D.
Fetal harm
- 48.Oxytocin should not be used
- A.
By the octo-mom
- B.
Before 37 weeks
- C.
Cephalocaudal disproportion
- 49.Prostaglandins is used as a uterine motility drug. It promotes uterine contraction, spontaneous labor, and delivery. It uses:
- A.
Termination of pregnancy between 12-20 weeks
- B.
Termination of pregnancy in the third trimester
- C.
May be used in a missed abortion of up to 28 weeks gestation
- D.
Topical ripen the cervix when applied the night before induction
- 50.Which uterine motility drugs are Prostaglandins?
- A.
Dinoprostone (Cervidil)
- B.
Carboprost tromethamine (Hemabate)
- C.
Misoprostol (Cytotec)
- D.
Ergotrate Maleate
- E.
Methergine
- 51.These SE of Prostaglandins are present because prostaglandin stimulates GI smooth muscle:
- A.
Nausea
- B.
Vomiting
- C.
Diarrhea
- 52.Ergot Alkaloid drugs include:
- A.
Ergotrate Maleate
- B.
Methergine
- 53.Uses of Ergot Alkaloids:
- A.
For induction of labor
- B.
Stop postpartum bleeding
- C.
To increase the strength, duration, and frequency of uterine contractions
- D.
Not for induction of labor
- E.
To maintain uterine strength thus stopping preterm labor
- 54.Ergots are a naturally occuring fungus found on rye plants. They are both partial antagonists and agonist at the trytaminergic, adrenergic, and dopaminergic receptors. What are the side effects of ergots?
- A.
Nausea
- B.
HA
- C.
Dizziness
- D.
Vertigo
- E.
Vomiting
- 55.Tocolytics : Suppress preterm labor with cervical change and decreases uterine muscle contractions. The following are examples of tocolytics:
- A.
Beta2 agonists
- B.
Cholinergics
- C.
Calcium Channel Blockers
- D.
Magnesium Sulfate
- E.
NSAIDS
- 56.Corticosteriods (prostaglandin inhibitors) in preterm labor are used tohelp promote fetal lung development/maturation/surfactant. True or False
- A.
True
- B.
False
- 57.Beta2 agonists side effects include cardio/ metabolic problems in the mother. Which Drugs are Beta2 agonist? How does it work?
- A.
Ritodrine
- B.
Nasdrone
- C.
Works by stimulating the uptake of intracellular calcium.
- D.
Terbutaline
- E.
Lack of calcium prevents activation of the contractile proteins of smooth muscle cell, creating uterine smooth muscle relaxation. A decrease in the intensity and duration of contractions results
- 58.Tocolytics: Magnesium Sulfate: Primary indication for mag sulfate is treatment of seizures in pre-eclampsia. Causes uterine relaxation through a direct effect on the uterine smooth muscle, Both the frequency and force of contactions are reduced. Labor is arrested at Mag levels ranging from?
- A.
8-7
- B.
6-5
- C.
9-8
- D.
10-9
- 59.Tocolytics: Magnesium Sulfate. At a Mag level of 8-10 you would see blurred vision, double vision and lethargy. Also the deep tendon relfexes are depressed or absent,
- A.
True
- B.
False
- 60.Tocolytics. Nifedipine is not FDA approved for preterm labor. Nifedipine works to inhibit the transmembranous influx of Ca ions. This factor inhibits the contractile process of uterine smooth muscle? What group of Tocolytics does Nifedipine belong to?
- A.
Beta2 Agonists
- B.
Magnesium Sulfates
- C.
Calcium Channel Blockers
- D.
NSAIDS
- 61.Androgens are used to treat ?
- A.
Delayed Puberty
- B.
Hypogonadism
- C.
Impotance
- D.
Palliation treatmenof post menopausal women with inoperable breast concer/ endometriosis
- E.
Oligiospermia (low sperm volume)
- 62.Phosphodiesterase-5 (PDE-5) inhibitors include which of the drugs for sexual dysfunction?
- A.
Sildenafil citrate (Viagra)
- B.
Phentolamine (Vasomax)
- C.
Vardenafil (Levitra)
- D.
Tadalafil (Cialis)
- 63.Sexual dysfunction: Phosphodiesterase-5 (PDE-5) inhibitors (Viagra, Cialis, Levitra) increases genital blood flow. Viagra should be taken 30-60 minutes before sexual activity. Cialis should be taken several hours before and may last up to 36 hours. PDE-5 interacts with other PDE receptors, patients that are contraindicated are individuals who take ? (which may cause hypotension)
- A.
Alpha blockers
- B.
Calcium channel blockers
- C.
Beta blockers
- D.
Nitrates
- 64.ED treatment may lead to these adverse effects:
- A.
Visual changes
- B.
Flushing
- C.
Aching
- D.
Priapism (painful and persistent erection)
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