Nursing Pharmacology Exam Quiz
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Questions from 4/12/2010.
- 1.Doxorubicin, bleomycin, vinbastine and dacarbazine are treatments for
- A.
Breast cancer
- B.
Testicular cancer
- C.
Ovarian cancer
- D.
Hodgkin's disease
- 2.Cisplatin is a treatment for
- A.
Breast cancer
- B.
Ovarian cancer
- C.
Testicular cancer
- D.
Hodgkin's disease
- 3.Which are treatments for ovarian cancer?
- A.
Carboplatin, cyclophosphamide, doxorubicin, paclitaxel and docetaxel
- B.
Tamoxifen, aromatase inhibitors, trastuzumab and fluorouracil
- C.
Vincristine, prednisone, methotrexate, mercaptopurine and nefarabine
- D.
Carmustine, lomustine, procarbazine and etoposide
- 4.Which is the only drug with effects on secondary progressive MS that reduces relapse?
- A.
Baclofen (Lioresal)
- B.
Prednisone
- C.
Tizanidine (Zanaflex)
- D.
Interferon beta-1b (Betaseron)
- 5.Which is the first drug approved to treat moderate alzheimer's disease?
- A.
Donepezil (Aricept)
- B.
Memantine (Namenda)
- C.
Galantamine (Razadyne)
- D.
Rivastigmine (Exelon)
- 6.Drugs for alzheimer's disease are mostly
- A.
Dopamine receptor agonists
- B.
Acetylcholinesterase inhibitors
- C.
Selective serotonin reuptake inhibitors
- D.
Cholinergic receptor antagonists
- 7.Drugs for parkinson's disease
- A.
Increase serotonin
- B.
Increase norepinephrine
- C.
Increase dopamine
- D.
Increase epinephrine
- 8.The most effective drug used to treat ALS is
- 9.The two drugs used to treat Huntington's disease are
- A.
Diazepam (Valium)
- B.
Benztropine (Cogentin)
- C.
Entacapone (Comtan)
- D.
Haloperidol (Haldol)
- 10.People with Parkinson's disease experience an increase/decrease in D1 receptors
- 11.Which of the following are definitive for AD?
- A.
Chorea
- B.
Amyloid deposits
- C.
Neurofibrillary tangles
- D.
Axonopathy
- 12.An increase in D2 receptors will stimulate/inhibit GABA
- 13.Cisplatin is a(n)
- A.
Alkylating drug
- B.
Microbial product
- C.
DNA synthesis inhibitor
- D.
Mitotic inhibitor
- 14.Which of the following are mitotic inhibitors?
- A.
Paclitaxel (Taxol)
- B.
Vincristine (Oncovin)
- C.
Vinblastine
- D.
Methotrexate
- 15.Decreased Ras/Raf GTPases will cause
- A.
Increased activity of Jun kinase
- B.
Increased activity of BCR-ABL kinase
- C.
Activation of BAD
- D.
Activation of STAT5
- 16.NF-kB acts to inhibit/stimulate apoptosis
- 17.In taxol neuropathy, one would expect
- A.
Accumulation of cytoskeleton
- B.
Disorganized mitrotubules and neurofilaments
- C.
Decrease in mitochondria
- D.
Accumulation of vesicles
- 18.Temsirolimus acts in which phase of the cell cycle?
- A.
G1
- B.
G0
- C.
S
- D.
G2
- 19.DNA synthesis inhibitors act in which phase of the cell cycle?
- A.
G1
- B.
G0
- C.
S
- D.
G2
- 20.Bleomysocin, etoposide and teniposide act on which phase of the cell cycle?
- A.
G2
- B.
G1
- C.
M
- D.
S
- 21.Mitotic inhibitors act on which phase of the cell cycle?
- A.
G2
- B.
G0
- C.
M
- D.
S
- 22.P-glycoprotein mechanism is
- A.
Active
- B.
Secondary active
- C.
Passive
- 23.Methotrexate inhibits the ____________ cycle
- 24.Parkinson's disease starts with a loss of neurons in the
- A.
Substantia nigra
- B.
Cerebral cortex
- C.
Thalamus
- D.
Globus pallidus
- 25.A patient experiences acute renal failure with severe nausea and vomiting. This patient is most likely being treated with
- A.
Prednisone
- B.
Bleomycin
- C.
Paclitaxel
- D.
Cisplatin
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