Nursing Pharmacology Exam Quiz

25 Questions | By Lisamoore13 | Last updated: Mar 22, 2022 | Total Attempts: 1694

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Questions from 4/12/2010.

Questions and Answers

1.

Doxorubicin, bleomycin, vinbastine and dacarbazine are treatments for
- A.
  
  Breast cancer
- B.
  
  Testicular cancer
- C.
  
  Ovarian cancer
- D.
  
  Hodgkin's disease
2.

Cisplatin is a treatment for
- A.
  
  Breast cancer
- B.
  
  Ovarian cancer
- C.
  
  Testicular cancer
- D.
  
  Hodgkin's disease
3.

Which are treatments for ovarian cancer?
- A.
  
  Carboplatin, cyclophosphamide, doxorubicin, paclitaxel and docetaxel
- B.
  
  Tamoxifen, aromatase inhibitors, trastuzumab and fluorouracil
- C.
  
  Vincristine, prednisone, methotrexate, mercaptopurine and nefarabine
- D.
  
  Carmustine, lomustine, procarbazine and etoposide
4.

Which is the only drug with effects on secondary progressive MS that reduces relapse?
- A.
  
  Baclofen (Lioresal)
- B.
  
  Prednisone
- C.
  
  Tizanidine (Zanaflex)
- D.
  
  Interferon beta-1b (Betaseron)
5.

Which is the first drug approved to treat moderate alzheimer's disease?
- A.
  
  Donepezil (Aricept)
- B.
  
  Memantine (Namenda)
- C.
  
  Galantamine (Razadyne)
- D.
  
  Rivastigmine (Exelon)
6.

Drugs for alzheimer's disease are mostly
- A.
  
  Dopamine receptor agonists
- B.
  
  Acetylcholinesterase inhibitors
- C.
  
  Selective serotonin reuptake inhibitors
- D.
  
  Cholinergic receptor antagonists
7.

Drugs for parkinson's disease
- A.
  
  Increase serotonin
- B.
  
  Increase norepinephrine
- C.
  
  Increase dopamine
- D.
  
  Increase epinephrine
8.

The most effective drug used to treat ALS is
9.

The two drugs used to treat Huntington's disease are
- A.
  
  Diazepam (Valium)
- B.
  
  Benztropine (Cogentin)
- C.
  
  Entacapone (Comtan)
- D.
  
  Haloperidol (Haldol)
10.

People with Parkinson's disease experience an increase/decrease in D1 receptors
11.

Which of the following are definitive for AD?
- A.
  
  Chorea
- B.
  
  Amyloid deposits
- C.
  
  Neurofibrillary tangles
- D.
  
  Axonopathy
12.

An increase in D2 receptors will stimulate/inhibit GABA
13.

Cisplatin is a(n)
- A.
  
  Alkylating drug
- B.
  
  Microbial product
- C.
  
  DNA synthesis inhibitor
- D.
  
  Mitotic inhibitor
14.

Which of the following are mitotic inhibitors?
- A.
  
  Paclitaxel (Taxol)
- B.
  
  Vincristine (Oncovin)
- C.
  
  Vinblastine
- D.
  
  Methotrexate
15.

Decreased Ras/Raf GTPases will cause
- A.
  
  Increased activity of Jun kinase
- B.
  
  Increased activity of BCR-ABL kinase
- C.
  
  Activation of BAD
- D.
  
  Activation of STAT5
16.

NF-kB acts to inhibit/stimulate apoptosis
17.

In taxol neuropathy, one would expect
- A.
  
  Accumulation of cytoskeleton
- B.
  
  Disorganized mitrotubules and neurofilaments
- C.
  
  Decrease in mitochondria
- D.
  
  Accumulation of vesicles
18.

Temsirolimus acts in which phase of the cell cycle?
- A.
  
  G1
- B.
  
  G0
- C.
  
  S
- D.
  
  G2
19.

DNA synthesis inhibitors act in which phase of the cell cycle?
- A.
  
  G1
- B.
  
  G0
- C.
  
  S
- D.
  
  G2
20.

Bleomysocin, etoposide and teniposide act on which phase of the cell cycle?
- A.
  
  G2
- B.
  
  G1
- C.
  
  M
- D.
  
  S
21.

Mitotic inhibitors act on which phase of the cell cycle?
- A.
  
  G2
- B.
  
  G0
- C.
  
  M
- D.
  
  S
22.

P-glycoprotein mechanism is
- A.
  
  Active
- B.
  
  Secondary active
- C.
  
  Passive
23.

Methotrexate inhibits the ____________ cycle
24.

Parkinson's disease starts with a loss of neurons in the
- A.
  
  Substantia nigra
- B.
  
  Cerebral cortex
- C.
  
  Thalamus
- D.
  
  Globus pallidus
25.

A patient experiences acute renal failure with severe nausea and vomiting. This patient is most likely being treated with
- A.
  
  Prednisone
- B.
  
  Bleomycin
- C.
  
  Paclitaxel
- D.
  
  Cisplatin