# Lipids: Dyslipidemia Diagnosis And Treatment

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| By Lee Ann
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Lee Ann
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Dyslipidemia is a condition in which a person has either an extremely high level or low level of lipoprotein cholesterol. Did you know that it is a major factor to heart attacks? Find out more on its diagnosis and treatment.

• 1.

### Which of the following appropriately represent the Friedewald Equation:

• A.

LDL = TC – HDL – TG’s/5

• B.

LDL = HDL + TG/5

• C.

LDL = TC – HDL - VLDL

• D.

TC = HDL + LDL + TG

A. LDL = TC – HDL – TG’s/5
Explanation
The Friedewald Equation is used to estimate LDL cholesterol levels. It calculates LDL cholesterol by subtracting HDL cholesterol and one-fifth of the triglyceride levels from the total cholesterol. The correct answer, "LDL = TC – HDL – TG’s/5," accurately represents the Friedewald Equation by including all the necessary components and following the correct mathematical operations.

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• 2.

### The VAP:

• A.

Is a comprehensive lipid analysis utilizing proprietary technology called the Vertical auto profile ultracentrifugation.

• B.

Offers a direct measure LDL.

• C.

Simultaneously measures cholesterol concentrations of all 5 lipoprotein classes and their subclasses in a nonfasting patient.

• D.

All of the above

D. All of the above
Explanation
The VAP is a comprehensive lipid analysis that utilizes a proprietary technology called the Vertical auto profile ultracentrifugation. This technique allows for a direct measurement of LDL, which is a key indicator of cardiovascular health. Additionally, the VAP is able to simultaneously measure cholesterol concentrations of all 5 lipoprotein classes and their subclasses in a nonfasting patient. Therefore, the correct answer is "All of the above."

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• 3.

### As TG’s decrease, the LDL cholesterol estimation becomes artificially lowered and progressively more inaccurate.

• A.

True

• B.

False

B. False
Explanation
As TG's (triglycerides) decrease, the estimation of LDL cholesterol becomes artificially elevated rather than lowered. This is because the calculation used to estimate LDL cholesterol levels assumes a certain ratio between triglycerides and LDL cholesterol. When triglyceride levels are low, this ratio becomes distorted, leading to an inaccurate estimation of LDL cholesterol levels. Therefore, the statement is false.

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• 4.

### Which of the following is a desirable blood lipid value?

• A.

High Total Cholesterol

• B.

High LDL

• C.

High HDL

• D.

High TG

• E.

None of the following are desirable

C. High HDL
Explanation
High HDL (High-density lipoprotein) is considered a desirable blood lipid value because it is commonly referred to as "good cholesterol." HDL helps remove excess cholesterol from the bloodstream and carries it back to the liver, where it is broken down and eliminated from the body. Having high levels of HDL is associated with a lower risk of cardiovascular diseases such as heart attacks and strokes. Therefore, maintaining high HDL levels is beneficial for overall health.

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• 5.

### ____________________is elevation of plasma cholesterol, triglycerides (TGs), or both, or a low high-density lipoprotein level that contributes to the development of atherosclerosis.

• A.

Hyperlipidemia

• B.

Dyslipidemia

• C.

Metabolic Syndrome

• D.

Hypoapolipoproteins

B. Dyslipidemia
Explanation
Dyslipidemia refers to the elevation of plasma cholesterol, triglycerides (TGs), or both, or a low high-density lipoprotein level, which contributes to the development of atherosclerosis. This condition involves an imbalance in lipid levels and can lead to the accumulation of fatty deposits in the arteries, increasing the risk of cardiovascular diseases such as heart attack and stroke.

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• 6.

### There are 2 types of Dyslipidemia, ______________, which is associated with __________________________& __________________ which is associated with______________________________. _______________________________________.

• A.

Primary; lifestyle; secondary; genetics

• B.

Essential; genetic; secondary; lifestyle

• C.

Hyperlipidemia; high cholesterol; hypolipidemia; low cholesterol

• D.

Primary; genetics; secondary; lifestyle and other causes

D. Primary; genetics; secondary; lifestyle and other causes
Explanation
Primary dyslipidemia is associated with genetics, meaning that it is caused by inherited genetic factors. Secondary dyslipidemia, on the other hand, is associated with lifestyle and other causes, such as obesity, diabetes, certain medications, and certain medical conditions. This means that secondary dyslipidemia is not primarily caused by genetics, but rather by external factors and underlying health conditions.

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• 7.

### A Triglyceride disorder is diagnosed by which of the following except:

• A.

Increased levels of Triglycerides (TG) (>100mg/dL)

• B.

Density Pattern B - Small LDL

• C.

High levels of HDL and HDL sub-types HDL2 & HDL3

• D.

Low levels of apoA1

• E.

↑ Remnant Lipoproteins

C. High levels of HDL and HDL sub-types HDL2 & HDL3
Explanation
High levels of HDL and HDL sub-types HDL2 & HDL3 are not indicative of a Triglyceride disorder. In fact, high levels of HDL cholesterol are considered beneficial for cardiovascular health. Triglyceride disorders are typically characterized by increased levels of triglycerides, density pattern B - small LDL, low levels of apoA1, and elevated remnant lipoproteins.

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• 8.

### The Basic Lipid Panel is a direct-measured lipid panel and provides measurements for 15 lipid components.

• A.

True

• B.

False

B. False
Explanation
The statement is false because the Basic Lipid Panel is not a direct-measured lipid panel that provides measurements for 15 lipid components.

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• 9.

### A Statin, Bile Acid Sequestrant, or a ezetimibe may be used to treat a Cholesterol-Rich Disorder

• A.

True

• B.

False

A. True
Explanation
A statin, bile acid sequestrant, or ezetimibe are commonly used medications to treat cholesterol-rich disorders. These medications work by different mechanisms to lower cholesterol levels in the body. Statins inhibit an enzyme involved in cholesterol synthesis, bile acid sequestrants bind to bile acids and prevent their reabsorption, and ezetimibe reduces the absorption of cholesterol from the intestines. Therefore, it is true that these medications can be used to treat cholesterol-rich disorders.

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• 10.

### All of the following are effective treatments for Triglyceride rich disorders except:

• A.

Fibrate

• B.

Niacin

• C.

Omega-3

• D.

Statins

• E.

All of the above

D. Statins
Explanation
Statins are not effective treatments for triglyceride-rich disorders. While statins are commonly used to lower cholesterol levels, they do not have a significant impact on triglyceride levels. Fibrate, niacin, and omega-3 are all effective treatments for triglyceride-rich disorders as they help to lower triglyceride levels in the blood.

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• 11.

### Even though the genetic component of cholesterol Lp(a) is an LDL with an additional protein tail, it does not respond to traditional LDL lowering agents.

• A.

True

• B.

False

A. True
Explanation
The statement is true because even though cholesterol Lp(a) has a genetic component similar to LDL (low-density lipoprotein), it does not respond to traditional LDL lowering agents. This means that the methods used to reduce LDL cholesterol levels, such as lifestyle changes or medication, may not be effective in lowering cholesterol Lp(a) levels. Therefore, it is important to consider alternative approaches for managing cholesterol Lp(a) levels.

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• Current Version
• Mar 21, 2023
Quiz Edited by
ProProfs Editorial Team
• Jun 11, 2014
Quiz Created by
Lee Ann

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