Treatment Of Dyslipidemia

21 Questions | Total Attempts: 593

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Treatment Of Dyslipidemia

This quiz discusses some of the agents used in patients with dyslipidemia.


Questions and Answers
  • 1. 
    Which of the following strategies is recommended as lifestyle changes for dyslipidemia?
    • A. 

      Diet

    • B. 

      Weight reduction

    • C. 

      Exercise

    • D. 

      Smoking cessation

    • E. 

      All of the above

  • 2. 
    Which of the following correctly describes the mechanism of action of niacin?
    • A. 

      Inhibits lipolysis in adipose tissue to disrupt mobilization of free fatty acids

    • B. 

      Decreases cholesterol synthesis in the liver

    • C. 

      Decreases absorption of cholesterol in the intestine

    • D. 

      Bind to bile salts in the intestine

  • 3. 
    Which of the following is false regarding the uses of niacin?
    • A. 

      It decreases VLDL and LDL

    • B. 

      It decreases triglycerides

    • C. 

      Its vitamin effect requires higher doses

    • D. 

      It increases HDL

  • 4. 
    • A. 

      Flushing

    • B. 

      Exacerbation of peptic ulcer

    • C. 

      Hyperglycemia

    • D. 

      Myopathy

    • E. 

      All of the above

  • 5. 
    • A. 

      Inhibit lipolysis in adipose tissue to disrupt mobilization of free fatty acids

    • B. 

      Agonize peroxisome proliferator-activated receptor alpha (PPARa)

    • C. 

      Decrease cholesterol synthesis in the liver

    • D. 

      Decrease absorption of cholesterol in the intestine

  • 6. 
    • A. 

      Triglycerides

    • B. 

      HDL

    • C. 

      LDL

    • D. 

      VLDL

  • 7. 
    Which of the following are clinical teachings regarding fibric acid derivatives?
    • A. 

      GI effects and myopathy may occur

    • B. 

      Can cause gallstones by increasing biliary cholesterol secretion

    • C. 

      May require reduction in warfarin dosage

    • D. 

      Concomitant use with statins may increase myopathy risk

    • E. 

      All of the above

  • 8. 
    • A. 

      Decrease production of cholesterol in the liver

    • B. 

      Decrease absorption of cholesterol in the intestine

    • C. 

      Bind to bile salts in the intestine

    • D. 

      Inhibit lipolysis in adipose tissue

  • 9. 
    • A. 

      Decrease LDL

    • B. 

      Decrease VLDL

    • C. 

      Decrease triglycerides

    • D. 

      Decrease HDL

  • 10. 
    • A. 

      Systemic toxicities

    • B. 

      Decreased absorption of other drugs

    • C. 

      Myopathy

    • D. 

      Abdominal discomfort

  • 11. 
    Which of the following is the correct mechanism of action of statins?
    • A. 

      Inhibit production of cholesterol in the liver

    • B. 

      Decrease cholesterol absorption in the intestine

    • C. 

      Bind bile salts in the intestine

    • D. 

      Stimulate lipoprotein lipase

  • 12. 
    • A. 

      Decreasing HDL

    • B. 

      Increasing HDL

    • C. 

      Decreasing LDL

    • D. 

      Decreasing triglycerides

  • 13. 
    • A. 

      AST/ALT elevations

    • B. 

      Myopathy

    • C. 

      Drug-drug interactions

    • D. 

      A and B

    • E. 

      All of the above

  • 14. 
    • A. 

      Simvastatin

    • B. 

      Fluvastatin

    • C. 

      Atorvastatin

    • D. 

      Lovastatin

  • 15. 
    • A. 

      It is contraindicated with azole antifgunals

    • B. 

      Its maximum dosage is 10 mg qhs with diltiazem or verapamil

    • C. 

      Its maximum dosage is 20 mg qhs with amlodipine

    • D. 

      80 mg qhs should be the start dose in every patient

  • 16. 
    Which of the following is the correct mechanism of action of ezetimibe?
    • A. 

      Inhibits cholesterol absorption in the intestine

    • B. 

      Decreases cholesterol synthesis in the liver

    • C. 

      Stimulates lipoprotein lipase

    • D. 

      Inhibits lipolysis in adipose tissue

  • 17. 
    • A. 

      It is synergistic with statins for LDL-lowering effects

    • B. 

      There are some GI effects associated with it

    • C. 

      It interacts with bile acid sequestrants

    • D. 

      It interacts with cyclosporine

    • E. 

      All of the above

  • 18. 
    • A. 

      They help decrease triglyceride synthesis from the liver

    • B. 

      Belching and altered taste are examples of adverse effects

    • C. 

      They are clinically proven to protect individuals from atherosclerosis

    • D. 

      They may potentially increase bleeding times

  • 19. 
    Which of the following correctly characterizes homozygous familial hypercholesterolemia?
    • A. 

      Individuals cannot make HDL

    • B. 

      Individuals cannot make LDL receptors

    • C. 

      Individuals cannot absorb cholesterol

    • D. 

      Individuals live long, healthy lives

  • 20. 
    According to the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Prevention Guidelines, which of the following is true?
    • A. 

      Emphasis is now placed on assessing cardiovascular risks rather than cholesterol goals

    • B. 

      There are "Four Statin Benefit Groups"

    • C. 

      Patients over 75 should receive high-intensity statin therapy

    • D. 

      Weight management and lifestyle changes are still recommended

    • E. 

      All of the above