Clinical Chemistry : Lipids, Lipoproteins, And Other Cardiac Markers

15 Questions | Total Attempts: 482

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Questions and Answers
  • 1. 
    This analyte is currently considered the most important value in assessing cardiac risk and directing therapy.
    • A. 

      High-Density Lipoprotein

    • B. 

      Low-Density Lipoprotein

    • C. 

      Troponin I

    • D. 

      Potassium

  • 2. 
    This is the umbrella medical term for hardening (and narrowing) of the arteries which are caused by several factors, one of these being high blood pressure.
    • A. 

      Atherosclerosis

    • B. 

      Arteriosclerosis

    • C. 

      All of the Above

    • D. 

      None of the Above

  • 3. 
    LDL can be computed by what equation?
    • A. 

      [ TC - HDL - ( TAG / 5 ) ]

    • B. 

      [ TC - HDL - ( 0.20 x TAG ) ]

    • C. 

      All of the Above

    • D. 

      None of the Above

  • 4. 
    Choose the incorrect non-enzymatic measurement step for cholesterol : description pair.
    • A. 

      Colorimetry : The absorbance of the colored product (red for the Leibermann-Burchardt Reaction and green for the Salkowski Reaction) is read at 410 nm.

    • B. 

      Extraction : Cholesterol is released from the lipoprotein, thus ensuring no protein interference.

    • C. 

      Saponification : KOH hydrolyzes cholesteryl esters to free cholesterol, thus removing possible colorimetric interference due to the former, because only the latter is to be measured for cholesterol.

    • D. 

      Precipitation : Digitonin is used to ensure no interference from other substances capable of absorbing light at 410 nm, such as bilirubin and hemoglobin.

  • 5. 
    This apolipoprotein is the cofactor for LCAT.
    • A. 

      Apo A-IV

    • B. 

      Apo A-III

    • C. 

      Apo A-II

    • D. 

      Apo A-I

  • 6. 
    The only lipoproteinemia that exhibits normal levels of TAG is:
    • A. 

      Type 1

    • B. 

      Type 2a

    • C. 

      Type 2b

    • D. 

      None of the Above

  • 7. 
    Which of these is not a cutaneous marker for coronary artery disease?
    • A. 

      Xanthelasma

    • B. 

      Arcus Juvenilis

    • C. 

      Acanthosis Nigricans

    • D. 

      None of the Above

  • 8. 
    Acanthocytes are known for being a hematological sign of the following except:
    • A. 

      Basser-Kornzweig Syndrome

    • B. 

      Abetalipoproteinemia

    • C. 

      Mutations of the XK gene

    • D. 

      None of the Above

  • 9. 
    Definitive diagnostic method for any and all lipoproteins:
    • A. 

      Gas Chromatography - Mass Spectroscopy

    • B. 

      Electrophoresis

    • C. 

      Polyanion Precipitation

    • D. 

      Ultracentrifugation

  • 10. 
    In the Three-Step Procedure (Ultracentrifugation + Precipitation + Abell-Kendall determination of supernatant cholesterol) for direct HDL measurement, what is used as the precipitant?
    • A. 

      Heparin-Magnesium

    • B. 

      Heparin-Manganese

    • C. 

      Heparan-Sulfate

    • D. 

      Heparan-Dihydrate

  • 11. 
    Products for all enzymatic methods of triglycerides have an absorbance measured at:
    • A. 

      360 nm

    • B. 

      350 nm

    • C. 

      340 nm

    • D. 

      330 nm

  • 12. 
    The assay for Lipoprotein (a) is:
    • A. 

      Immunospectroscopy

    • B. 

      Immunonephelometry

    • C. 

      Immunoturbidimetry

    • D. 

      Immunofluoroscopy

  • 13. 
    What are not the troponin forms released following cardiac myofibril necrosis?
    • A. 

      Troponin T

    • B. 

      Troponin I

    • C. 

      Troponin C

    • D. 

      None of the Above

  • 14. 
    The B-type Natriuretic Peptide proves what function of the heart?
    • A. 

      Cardiovascular

    • B. 

      Exocrine

    • C. 

      Endocrine

    • D. 

      A and C

  • 15. 
    What is the test that new-generation doctors request in tandem with LDL-C to determine risk for cardiac dysfunction?
    • A. 

      Serum Amyloid Protein A

    • B. 

      C-Reactive Protein

    • C. 

      High-Sensitivity C-Reactive Protein

    • D. 

      B and C

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