Take This Simple Genetics Trivia Quiz !

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Take This Simple Genetics Trivia Quiz !

Take this simple genetics trivia quiz if you want to get a deeper understanding on the human anatomy and how the genes inside us operate. Genetics is basically the study of human genes, which determine body features and what our bodies become. Take up the quiz below and see how much you know on the subject. All the very best!


Questions and Answers
  • 1. 
    Ribozymes catalyze which of the following reactions ?
    • A. 

      DNA synthesis

    • B. 

      Transcription

    • C. 

      RNA slicing

    • D. 

      Protein hydrolysis

  • 2. 
    Operons
    • A. 

      Are commonly found in eucaryotic cells

    • B. 

      Are transcripbed by RNA polymerase 2

    • C. 

      Contain a cluster of genes transcribed as a single mRNA

    • D. 

      Can only be regulated by gene activator protein

  • 3. 
    Which of the following statements about the Lac operons is false ?
    • A. 

      The lac repressor binds when lactose is present in the cells

    • B. 

      Even when the CAP activator is bound to DNA , if lactose is not present , the Lac operon will not

    • C. 

      The cap activator can only bind DNA when it is bound cAMP

    • D. 

      The Lac operon only produces RNA when lactose is present and glucose is absent

  • 4. 
    The lac operon in E.coli is regulated by lactose when _______an ________ of transcription
    • A. 

      Activates,activator

    • B. 

      Inactivates,activator

    • C. 

      Activates,repressor

    • D. 

      Inactivates,repressor

  • 5. 
    Eukaroyotic gene repressor protein are thought to act by binding to
    • A. 

      DNA sites in competition with activating proteins

    • B. 

      Specific activation protein , preventing their bind to DNA

    • C. 

      Basal transcription factors, inhibiting transcription

    • D. 

      All of the above

  • 6. 
    The large multisubunit complex that links the general transciption fators to the gene- specific transcription factor is called
    • A. 

      The large multisubunit complex that links the general transcription fcator to the gene-specific transcription factors is the transcription complex

    • B. 

      Mediator

    • C. 

      The operon

    • D. 

      TBP

  • 7. 
    Which of the following best describes the ability of an enhancer to mediate transcription from very distant sites
    • A. 

      Loop of DNA can occur, allowing the transcription factor to get ino the proximity of the RNA polymerase

    • B. 

      When needed, enhacer are sliced into a region of closer proximity to the promoter

    • C. 

      They are recognized by RNA polymerase , which bind and then slide down the promoter toward the gene

    • D. 

      All of the above

  • 8. 
    The major pathway for molecules to pass into and out of the nucles is through
    • A. 

      Gap junction between the nuclear envelopes membranes

    • B. 

      Porin channels in the nuclear envelopes

    • C. 

      Nuclear pore complexes

    • D. 

      Diffusion through the membrane bilyers of the nuclear envelope

  • 9. 
    The nuclear envelope is continous with the
    • A. 

      Mitochondrial outer membrane

    • B. 

      Golgi apparatus

    • C. 

      Rough endoplastmic reticulum

    • D. 

      Plasma membrane

  • 10. 
    Release of RNA polymerase 2 initate transcription appears to ben the direct results of
    • A. 

      Binding to TAFs to the polymerase

    • B. 

      Unwinding of the DNA by helicases

    • C. 

      Phosphorylation of RNA polymerase by a protein kinase

    • D. 

      Removal of the nuclesome occupying the promotor site

  • 11. 
    Export of RNAs from the nucleus occurs primarily by
    • A. 

      Passive diffusion through nuclear pore complexes

    • B. 

      Conscription insertion through nuclear envelope membrane protein pores

    • C. 

      Selective transport through nuclear pore complexes in association with proteins

    • D. 

      Release from nucleus when it breaks down at mitosis

  • 12. 
    Highly condensed, transciptionally inactive chromatin is called
    • A. 

      Euchromatin

    • B. 

      Heterochromatin

    • C. 

      A chromatin domain

    • D. 

      Histone-containing- chromatin

  • 13. 
    Which of the following statments are true ?
    • A. 

      Ribsomes are large RNA strctures compose solely of rRNA

    • B. 

      Ribsomes are synthesized entirely in the cytoplasm

    • C. 

      RRNA contains the catalytic activity that join amino acids together

    • D. 

      A ribosome binds one tRNA at a time

  • 14. 
    The first step in forming a transcription complex mRNA transcription is binding to which of the following to the TATA box ?
    • A. 

      TFIA

    • B. 

      TFIIA

    • C. 

      TFID

    • D. 

      TFIID

  • 15. 
    Which of the following is not part of transciption complex
    • A. 

      TBP

    • B. 

      TAFs

    • C. 

      TFIIH

    • D. 

      RFC

  • 16. 
    Translation of mRNAs starts at
    • A. 

      The 3' end of mRNA

    • B. 

      A site downstream of a 3' untranslated region

    • C. 

      The 5; end of the mRNA

    • D. 

      A site downstream of a 5' untranslated region

  • 17. 
    Eukaryotic ribosomes recognized and intially bind to what structure on mRNA
    • A. 

      A Shine-Dalgarno sequence

    • B. 

      The 7-methlyguansine cap

    • C. 

      A TATA sequence

    • D. 

      An AUG initiation codon

  • 18. 
    The firsr amino acid that initates the eukaryotic polypeptide is which of the following ?
    • A. 

      Any amino acid

    • B. 

      Glutamine

    • C. 

      Methionine

    • D. 

      N-formylmethionine

  • 19. 
    DNA replication is 
    • A. 

      The replication orgins

    • B. 

      The telomeres

    • C. 

      The start side

    • D. 

      The centromeres

  • 20. 
    Telomeres function to 
    • A. 

      Protect chromosome ends from degradation

    • B. 

      Protect chromosome ends from joining

    • C. 

      Provide a site for replication of chromosome ends

    • D. 

      All of the above

  • 21. 
    Origins of replication are the
    • A. 

      Mircotuble binding sites on chromosomes

    • B. 

      Sites where DNA transcription start

    • C. 

      Binding sites for the protein complex that initates DNA synthesis

    • D. 

      Forks where DNA replication is occuring

  • 22. 
    What provides the energy for DNA polymerization 
    • A. 

      The hydrolysis of ATP(releasing Pi)

    • B. 

      The hydrolysis of CTP(releasing Pi)

    • C. 

      The hydrolysis of incoming nucleoside triphosophate (relasing PPI)

    • D. 

      The hydrolysis of GTP (releasing Pi)

  • 23. 
    DNA synthesis proceeds
    • A. 

      In the 3' to 5' direction

    • B. 

      In the 5' to 3' direction

    • C. 

      From left to right

    • D. 

      In both directions at once

  • 24. 
    Replication of DNA requires a primer to initiate DNA synthesis because 
    • A. 

      DNA polymerase can add its first nucleotide only to an RNA chain

    • B. 

      DNA polymerase can add a nucleoside only to a base- paired nucleotide with a free 3' end

    • C. 

      DNA polymerase can polymerize DNA only in a short fragment

    • D. 

      DNA polymerase had a 3' to 5' exonuclease activity

  • 25. 
    Short segments of newly synthesized DNA on the lagging strand of DNA are called
    • A. 

      Replicons

    • B. 

      Okazki fragments

    • C. 

      Origins of replication

    • D. 

      Lagging fragments

  • 26. 
    Primase synthesizes short sequence of ________ complementary to the __________ strand
    • A. 

      DNA; leading

    • B. 

      RNA; leading

    • C. 

      DNA; Lagging

    • D. 

      RNA; Lagging

  • 27. 
    Free rotation of one cut DNA strand around one uncut strand is the primary function of  
    • A. 

      Topoisomerase 1

    • B. 

      Topoisomerase2

    • C. 

      DNA helicase

    • D. 

      DNA polymerase

  • 28. 
    The lagging strand is synthesized discontinously at the replication fork becuase
    • A. 

      The lagging strand template is discontinous

    • B. 

      DNA polymerase always falls off the template DNA every ten nucleotide or so

    • C. 

      DNA polymerase can polymerize nucleotides only in the 5' to 3' direction

    • D. 

      None of above

  • 29. 
    Which of the following statements concerning elongation of DNA at the replication fork is false
    • A. 

      The leading strand is synthesized continuouslyt in the direction of replication fork movement

    • B. 

      The lagging strand is synthesized in Okazki fragments backwards from overall direction of replication

    • C. 

      The Okazaki fragments are joined by the action of DNA ligase

    • D. 

      Both strands are synthesized continuously are the replication fork

  • 30. 
    Prolieration cell nuclear antigen (PCNA) is an _________ in eukaryotes
    • A. 

      DNA polymerase

    • B. 

      Sliding clamp protein

    • C. 

      Single-strand DNA-binding protein

    • D. 

      Origin-of-replication-binding protein

  • 31. 
    The short fragment of DNA produced during DNA replication are joined together by
    • A. 

      RNA polymerase

    • B. 

      DNA helicase

    • C. 

      DNA ligase

    • D. 

      DNA polymerase

  • 32. 
    The proofreading property of DNA polymerase is due to its _______activity 
    • A. 

      3' to 5' exnuclease

    • B. 

      5' to 3' exonuclease

    • C. 

      Excision repair

    • D. 

      Mismatch repair

  • 33. 
    How often does DNA polymerase make an  error during DNA replication:
    • A. 

      One error in every 100 nucleotide pairs

    • B. 

      One error in every 1,000 nucleotide pairs

    • C. 

      One error in every 10,000 nucleotide pairs

    • D. 

      One every 10,000,000 nucleotide pairs

  • 34. 
    When does DNA polymerase preform its proofreading function on misreading nucleotides
    • A. 

      Before adding the next nucleotide in the chain

    • B. 

      After adding a stretch of about 100 more nucleotides

    • C. 

      After adding a stretch of about 100 more nucleotides

    • D. 

      Both A and C

  • 35. 
    If uncorrected deamination of cytosine in DNA is most likely to lead to
    • A. 

      Substitution of AT base pair for a CG base pair

    • B. 

      Deletion of the altered CG base pair from the DNA

    • C. 

      Conversion of the DNA into RNA

    • D. 

      None of the above

  • 36. 
    The human disease in which affected indidvuals are extremely sensitive to sunlight and develop multiple skin cause cancers on exposed area is called 
    • A. 

      Melanonma

    • B. 

      Zero pigment disease

    • C. 

      Xeroderma pigmentosum

    • D. 

      Cockayne syndrome

  • 37. 
    The human disease in which affected individuals are extremly sensitive to sunlight and develop multiple skin cancers on exposed areas is called
    • A. 

      Melanonma

    • B. 

      Zero pigments disease

    • C. 

      Xeroderma pigmentosum

    • D. 

      Cockayne's syndrome

  • 38. 
    During mismatch repair E.coli the partenal (template) strand is recognized by 
    • A. 

      Single-stranded breaks

    • B. 

      Glycosylated adenines

    • C. 

      Methylated adenines

    • D. 

      Methylation of o6 position of guanine residues.

  • 39. 
    Recombination of DNA strands is important because it can 
    • A. 

      Rearrange DNA sequences to change gene expression during development

    • B. 

      Repair damaged sequence

    • C. 

      Increase genetic diversity in the next generation

    • D. 

      All of above

  • 40. 
    All viruses
    • A. 

      Have single-stranded protein

    • B. 

      Lyse the cells they infect

    • C. 

      Contain both nucleic acid and protein

    • D. 

      Have the same size genomes

  • 41. 
    Eukaryotic gene activation s facilitated by
    • A. 

      Acetylation of histone

    • B. 

      Deacetylation

    • C. 

      The action of nucleosome remodeling factors.

    • D. 

      Both a and c

  • 42. 
    Combinatorial control of gene expression ________
    • A. 

      Involves every gene using a different combination of transcriptional regulator for its proper

    • B. 

      Involves groups of transcriptional regulators working together to determine the expression of gene

    • C. 

      Involves only the use of gene activator used together to regulate genes appropriately

    • D. 

      Is seen only when genes are arranged in operons

  • 43. 
    The role of the sigma factor in prokaryote transcription is to 
    • A. 

      Unwind DNA during transcription

    • B. 

      Provide specificity to binding to the promoter region

    • C. 

      Recognize the transcription initiation site

    • D. 

      Terminate transcription

  • 44. 
    Ribozymes catalyze which of the following reactions?
    • A. 

      DNA synthesis

    • B. 

      RNA slicing

    • C. 

      Option 3

    • D. 

      Protein hydrolysis