Pedigree Analysis Quiz Questions With Answers

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    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. What is the inheritance pattern for this trait? - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. What is the inheritance pattern for this trait?

    • Codominant Inheritance
    • Autosomal recessive
    • Sex linked dominant
    • X-Linked Dominant Inheritance
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About This Quiz


The Pedigree Analysis Quiz is designed to test your understanding of genetic inheritance through the analysis of family trees. In this quiz, you will encounter a series of pedigree analysis questions that challenge your ability to interpret the inheritance patterns of traits across generations. These questions will cover a variety of concepts such as dominant, recessive, and sex-linked inheritance, allowing See moreyou to apply Mendelian principles to real-life scenarios.

By examining how genetic traits are passed down through family members, you will enhance your ability to predict the likelihood of these traits appearing in future generations. If you are preparing for exams or seeking to solidify your knowledge, this quiz offers a comprehensive review of pedigree analysis.

Pedigree Analysis Quiz Questions With Answers - Quiz

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  • 2. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 1 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 1 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Based on the information provided, the affected individuals in the pedigree are shown shaded. Since none of the marriage partners from outside these two families are heterozygous for the trait, it can be inferred that the trait is likely inherited in an autosomal recessive manner. Individual #1 is not affected, so they could either be homozygous dominant (AA) or heterozygous (Aa) for the trait. Since the trait is not shown in either of their parents, it is more likely that individual #1 is heterozygous (Aa) for the trait.

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  • 3. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 2 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 2 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Individual #2 can have a genotype of Aa because they are affected by the trait, which means they must have at least one copy of the dominant allele A. However, since they are affected, they must also have a copy of the recessive allele a. Therefore, their genotype can be Aa.

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  • 4. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 3 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 3 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. AA
    Explanation
    Individual #3 must have the genotype AA because the trait is dominant and both of their parents are affected (shaded), meaning they have at least one copy of the dominant allele. Since none of the marriage partners from outside the families are heterozygous for the trait, it can be inferred that both parents of individual #3 are homozygous dominant (AA).

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  • 5. 

    In a pedigree chart, if two unaffected individuals have a child with the trait, what is the most likely mode of inheritance for this trait?

    • Autosomal dominant 

    • Autosomal recessive 

    • X-linked dominant

    • X-linked recessive

    Correct Answer
    A. Autosomal recessive 
    Explanation
    If two unaffected individuals (neither of them has the trait) have a child with the trait, the most likely mode of inheritance for this trait is autosomal recessive. 

    In autosomal recessive inheritance, the trait is typically "hidden" or not expressed in carriers (heterozygous individuals), but it can be expressed when two carriers have a child together, and both pass on the recessive allele for the trait. This means that two unaffected parents can have a child with the trait if they both carry a single copy of the recessive allele and pass it on to their child. This scenario is characteristic of autosomal recessive inheritance.

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  • 6. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 5 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 5 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Individual #5 is affected, meaning they have at least one copy of the dominant allele. Since they are not homozygous dominant (as marriage partners outside the family are not heterozygous), the only possible genotype for individual #5 is Aa, having one dominant allele and one recessive allele.

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  • 7. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 6 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 6 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Individual #6 must have the genotype aa because the trait is dominant and both of their parents are affected, meaning they must carry at least one copy of the dominant allele. Since the trait is not present in any of the marriage partners from outside the two families, it can be concluded that the trait is not inherited from any outside source and must be inherited from the affected parents.

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  • 8. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 7 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 7 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Individual #7 can have the genotype Aa. This is because the affected individuals in the pedigree are shown as shaded, indicating that they have the dominant trait. Since individual #7 is affected, they must have at least one copy of the dominant allele, which is represented by "A". However, since none of the marriage partners from outside these two families are heterozygous for the trait, individual #7 cannot have the genotype AA. Therefore, the only possible genotype for individual #7 is Aa.

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  • 9. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 8 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 8 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Individual #8 can have the genotype Aa. This is because the trait is dominant, and individual #8 is affected, which means they must have at least one dominant allele. Since none of the marriage partners from outside the families are heterozygous for the trait, it is likely that individual #8 inherited the dominant allele from one of their parents who is affected. Therefore, individual #8 can have the genotype Aa.

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  • 10. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 9 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 9 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer(s)
    A. AA
    A. Aa
    Explanation
    Based on the information given, we can determine that the trait being referred to is dominant. Since none of the marriage partners from outside these two families are heterozygous for the trait, it implies that both parents of individual #9 are affected. Therefore, individual #9 can have either the genotype AA or Aa.

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  • 11. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 10 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 10 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer
    A. Aa
    Explanation
    Based on the information provided, we know that the trait is recessive since none of the marriage partners from outside these two families are heterozygous for the trait. Individual #10 is affected, which means they must have two copies of the recessive allele. Therefore, the genotype of individual #10 can only be aa.

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  • 12. 
    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 11 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes) - ProProfs

    In the above pedigree, the affected individuals are shown shaded.  None of the marriage partners from outside these two families are heterozygous for the trait. Indicate the genotype(s) of individual # 11 (Allow the dominant trait to be “A” and the recessive trait to be “a” – NOTE: Some may have two possible genotypes)

    • AA

    • Aa

    • Aa

    Correct Answer(s)
    A. AA
    A. Aa
    Explanation
    Individual #11 is the child of two affected individuals, who are both shaded in the pedigree. Since the trait is shown as shaded, it is likely a dominant trait. Both affected individuals could either be heterozygous (Aa) or homozygous dominant (AA). Therefore, individual #11 could have either the genotype aa or AA.

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  • 13. 
    What pattern of inheritance does this pedigree demonstrate? - ProProfs

    What pattern of inheritance does this pedigree demonstrate?

    • Autosomal

    • Sex linked

    Correct Answer
    A. Sex linked
    Explanation
    The pedigree shows more males being affected than females, which suggests a sex-linked inheritance pattern. In sex-linked disorders, the gene responsible for the trait is located on the sex chromosomes (usually the X chromosome). Since males only have one X chromosome, they are more likely to express the trait if they inherit the affected X. Females, with two X chromosomes, are less likely to express the trait unless they inherit two copies of the affected gene. Therefore, the inheritance pattern here is sex-linked.

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  • 14. 
    What pattern of inheritance does this pedigree demonstrate?  (HINT: Look carefully practice with genotypes if necessary) - ProProfs

    What pattern of inheritance does this pedigree demonstrate?  (HINT: Look carefully practice with genotypes if necessary)

    • Dominant

    • Recessive

    Correct Answer
    A. Dominant
    Explanation
    In this pedigree, the trait is dominant because the affected female (#4) is heterozygous (XBXb) and has a son who expresses the trait. The father (#3) is XbY, meaning he passed the Y chromosome to his son, but the son still inherits the dominant allele (XB) from his mother. This confirms that the inheritance is dominant. Dominant traits are typically expressed even if only one allele is present, which is the case here.

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  • 15. 
    Indicate the pattern of inheritance observed for pedigree A. - ProProfs

    Indicate the pattern of inheritance observed for pedigree A.

    • Dominant

    • Recessive

    Correct Answer
    A. Recessive
    Explanation
    Pedigree A suggests a recessive inheritance pattern because the trait skips a generation. In recessive inheritance, individuals who do not show the trait can still carry the gene and pass it on. It can appear in offspring only if both parents are carriers of the recessive allele. In this case, neither parent expresses the trait, but one child does, indicating the trait is recessive. It could also be X-linked recessive, but without additional information, autosomal recessive is a reasonable conclusion.

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  • 16. 
    Indicate the pattern of inheritance observed for pedigree B. - ProProfs

    Indicate the pattern of inheritance observed for pedigree B.

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Sex linked dominant
    Explanation
    In this pedigree, the affected father passes the trait to all his daughters, making them affected, which is characteristic of X-linked dominant inheritance. He does not pass the affected allele to his sons, who remain unaffected, also consistent with this pattern. While autosomal dominant with heterozygous parents could theoretically produce this outcome in a small family, the direct transmission from an affected father to all daughters strongly suggests an X-linked dominant mode of inheritance. The observed pattern effectively rules out autosomal recessive and X-linked recessive inheritance.

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  • 17. 
    Indicate the pattern of inheritance observed for pedigree C. - ProProfs

    Indicate the pattern of inheritance observed for pedigree C.

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Autosomal recessive
    Explanation
    In Pedigree C, neither parent expresses the trait, but both a son and a daughter do. This suggests an autosomal recessive inheritance pattern, where both parents are carriers of the recessive allele but do not show the trait themselves. The children express the trait because they inherit two copies of the recessive allele, one from each parent. Autosomal recessive traits can skip generations if the carriers do not express the trait but pass it on to their offspring.

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  • 18. 
    Indicate the pattern of inheritance observed for pedigree D. - ProProfs

    Indicate the pattern of inheritance observed for pedigree D.

    • Dominant

    • Recessive

    Correct Answer
    A. Dominant
    Explanation
    Pedigree D suggests a dominant inheritance pattern because the trait appears in every generation, which is characteristic of dominant inheritance. In dominant inheritance, only one copy of the mutated gene is necessary for the trait to be expressed. The fact that the trait is passed down to offspring in each generation, and both males and females are affected, supports the conclusion that the trait follows a dominant inheritance pattern. Additionally, the trait could be X-linked dominant, as both daughters express the trait.

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  • 19. 
    Indicate the pattern of inheritance observed for pedigree E. - ProProfs

    Indicate the pattern of inheritance observed for pedigree E.

    • Autosomal Recessive

    • X-Linked

    • Y-Linked

    Correct Answer
    A. Autosomal Recessive
    Explanation
    In Pedigree E, the trait appears to follow an autosomal recessive inheritance pattern. This is because it can skip generations, meaning the trait may not appear in each generation, but can still be passed on by carriers. Both males and females are equally likely to inherit the trait, which is a hallmark of autosomal recessive inheritance. The trait is typically expressed in individuals who inherit two copies of the recessive allele, one from each parent.

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  • 20. 
    What pattern of inheritance is shown in the pedigree? - ProProfs

    What pattern of inheritance is shown in the pedigree?

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Autosomal recessive
    Explanation
    Autosomal recessive inheritance is suggested in this pedigree, as two unaffected parents have a child who expresses the trait. This scenario is typical of autosomal recessive inheritance, where both parents are carriers of the recessive allele but do not show the trait themselves. The trait is expressed in the child when they inherit two copies of the recessive allele, one from each parent. This pattern can also apply to other types of inheritance, but autosomal recessive fits the description here.

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  • 21. 
    What pattern of inheritance is shown in the pedigree? - ProProfs

    What pattern of inheritance is shown in the pedigree?

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Autosomal recessive
    Explanation
    The trait appears to skip generations in family I and family III, with equal numbers of affected males and females. This suggests autosomal recessive inheritance. For recessive traits, both parents must be carriers (heterozygous) for the trait to be expressed in their offspring, which may result in the trait being passed down through generations without being expressed in each generation.

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  • 22. 
    What pattern of inheritance is shown in the pedigree? - ProProfs

    What pattern of inheritance is shown in the pedigree?

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Sex linked recessive
    Explanation
    The pedigree indicates that only females are carriers of the trait, and more males than females are affected. This suggests sex-linked recessive inheritance. In such a pattern, males are typically affected because they have only one X chromosome, while females can be carriers if they have one affected X chromosome and one unaffected X chromosome.

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  • 23. 
    What pattern of inheritance is shown in the pedigree? - ProProfs

    What pattern of inheritance is shown in the pedigree?

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Autosomal dominant
    Explanation
    Huntington's Disease, a well-known autosomal dominant disorder, follows a pattern where only one copy of the altered gene is sufficient to cause the disease. The trait appears in every generation, and both males and females can be affected. This pattern is clearly demonstrated in the pedigree, where affected individuals have at least one affected parent.

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  • 24. 
    What pattern of inheritance is shown in the pedigree? - ProProfs

    What pattern of inheritance is shown in the pedigree?

    • Autosomal dominant

    • Autosomal recessive

    • Sex linked dominant

    • Sex linked recessive

    Correct Answer
    A. Autosomal recessive
    Explanation
    The pedigree shows that the trait skips generations I and III, and both males and females are carriers. This suggests autosomal recessive inheritance. Recessive traits often skip generations, and both parents must be carriers of the recessive allele for the trait to appear in their offspring.

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  • Apr 15, 2025
    Quiz Edited by
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  • Feb 06, 2016
    Quiz Created by
    J Cook

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