Is excreted mainly by the kidney
Can cross the placental barrier easily
Is well absorbed from the intestine
Accumulates in the cellular lipids
It is not associated with atrophy of adrenal glands
It does not occur in patients receiving inhaled steroids
It should be expected in anyone receiving greater than 5mg of prednisolone daily
Following cessation, the stress response normalizes after 8 weeks
Post Marketing studies
All of above
Gives predictable blood levels
From lower 1/3rd avoids first pass & upper 2/3rds doesn’t
None undergoes first pass metabolism
All of it undergoes first pass metabolism
Spindle shaped lignified fibers and sclerides
Cluster crystals of calcium oxalate and sclerides
Non lignified vessels and sac shaped starch grains
Non lignified vessels and sclerides
Deep yellow colour
No reaction but only charring
Deep blue colour
Deep red colour
1-d, 2-c, 3-a, 4-b
1-a, 2-b, 3-d, 4-c
1-c, 2-d, 3-b, 4-a
1-b, 2-a, 3-c, 4-d
Prism of calcium oxalate
Calcium carbonate and silica
Rosetters of calcium oxalate
Rhaphides of calcium oxalate
An enzyme provides a reaction surface and a suitable environment for the reaction to take place
An enzyme binds reactants such that they are positioned correctly and can attain their transition-state configurations
An enzyme allows the reaction to go through a less stable transition state than would normally be the case
An enzyme can weaken bonds in reactants through the binding process
An active site is normally a hollow or cleft on the surface of an enzyme.
An active site is normally hydrophilic in nature.
Substrates fit into active sites and bind to functional groups within the active site.
An active site contains amino acids which are important to the binding process and the catalytic mechanism.
It is a binding site containing amino acids with aliphatic side chains.
It is a binding site that can accept a wide variety of differently shaped molecules.
It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.
It is a description of an active site which has undergone an induced fit.