Mpharm-cet Test No.1

50 Questions | Total Attempts: 170

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Pharmacology Quizzes & Trivia

MPHARM-CET TEST NO. 1Designed by Dr. Anwar R. ShaikhCourtesy:1) Dr. Aman B. Upaganlawar (M. Pharm,PhD,MAMS)Associate Professor, Department of Pharmacology. SNJBs SSDJ College of Pharmacy,Neminagar,Chandwad. Dist:Nashik:423 1012) Mr. C V PanchalAsst. ProfessorDept. Of Pharmacognosy,Maharashtra College of Pharmacy,Nilanga, Dist. Latur, PIN-413521


Questions and Answers
  • 1. 
    All of the following hormones have cell surface receptors except
    • A. 

      Adrenaline

    • B. 

      Growth Hormone

    • C. 

      Insulin

    • D. 

      Thyroxin

  • 2. 
    A highly ionized drug
    • A. 

      Is excreted mainly by the kidney

    • B. 

      Can cross the placental barrier easily

    • C. 

      Is well absorbed from the intestine

    • D. 

      Accumulates in the cellular lipids

  • 3. 
    Which one of the following is true of adrenal suppression due to steroid therapy?
    • A. 

      It is not associated with atrophy of adrenal glands

    • B. 

      It does not occur in patients receiving inhaled steroids

    • C. 

      It should be expected in anyone receiving greater than 5mg of prednisolone daily

    • D. 

      Following cessation, the stress response normalizes after 8 weeks

  • 4. 
    With which of the following theophylline has an antagonistic interaction?
    • A. 

      Histamine receptors

    • B. 

      Bradykinin receptors

    • C. 

      Adenosine receptors

    • D. 

      Imidazoline receptors

  • 5. 
    Which one of the following drugs increases gastrointestinal motility?
    • A. 

      Glycopyrrolate

    • B. 

      Atropine

    • C. 

      Neostigmine

    • D. 

      Fentanyl

  • 6. 
    Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of flux?
    • A. 

      Ondansetron

    • B. 

      Metaclopramide

    • C. 

      Sodium citrate

    • D. 

      Atropine

  • 7. 
    Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of flux?
    • A. 

      Ondansetron

    • B. 

      Metaclopramide

    • C. 

      Sodium citrate

    • D. 

      Atropine

  • 8. 
    Inverse agonist of benzodiazepine receptor is
    • A. 

      Phenobarbitone

    • B. 

      Flumazenil

    • C. 

      Beta-carboline

    • D. 

      Gabapentin

  • 9. 
    1. At the end of phase III clinical trial the drug will be submitted to the relevant regulatory authority for:
    • A. 

      Licensing

    • B. 

      Evaluation

    • C. 

      Post Marketing studies

    • D. 

      All of above

  • 10. 
    Rectal administration of drugs:
    • A. 

      Gives predictable blood levels

    • B. 

      From lower 1/3rd avoids first pass & upper 2/3rds doesn’t

    • C. 

      None undergoes first pass metabolism

    • D. 

      All of it undergoes first pass metabolism

  • 11. 
    Different species of Ephedra can be identified by observing the nature of 
    • A. 

      Inner surface

    • B. 

      Outer surface

    • C. 

      Trichomes

    • D. 

      Scaly Leaves

  • 12. 
    Indian Rhubarb can be  distinguished from Rhapontic Rhubarb by the flurorescence it emits under UV light, Indian Rhubarb gives:
    • A. 

      Deep yellow

    • B. 

      Deep Violate

    • C. 

      Orange

    • D. 

      Pale Green

  • 13. 
    Genetically modified species of papaver namely papaver bracetum and papver oriental contain the predominant alkaloid:
    • A. 

      Morphine

    • B. 

      Codeine

    • C. 

      Thebaine

    • D. 

      Narcotine

  • 14. 
    A substance used  for the modification of silica gel for reversed phase TLC is:
    • A. 

      Benzene

    • B. 

      Glycerine

    • C. 

      Silicone Oil

    • D. 

      Ether

  • 15. 
    Klunge's Test is for the identification of:
    • A. 

      Barbaloin

    • B. 

      Isobarbaloin

    • C. 

      Alionosides

    • D. 

      Aleosin

  • 16. 
    Microscopic character of Ginger Rhizome are:
    • A. 

      Spindle shaped lignified fibers and sclerides

    • B. 

      Cluster crystals of calcium oxalate and sclerides

    • C. 

      Non lignified vessels and sac shaped starch grains

    • D. 

      Non lignified vessels and sclerides

  • 17. 
    A transeverse section of the root of Glycerrhiza glabra when treated with 80% Sulphuric acid gives:
    • A. 

      Deep yellow colour

    • B. 

      No reaction but only charring

    • C. 

      Deep blue colour

    • D. 

      Deep red colour

  • 18. 
    A naturally occuring amino acid which does not have a chiral centre is :
    • A. 

      Glycine

    • B. 

      Alanine

    • C. 

      Tryptophane

    • D. 

      Tyrosine

  • 19. 
    Match Group I with II:Group I                       Group II1. Gentisin               a. Flavonol2. Genistein             b. Flavone3. Apigenin              c. Xanthone4. Quercetin            d. Isoflavone
    • A. 

      1-d, 2-c, 3-a, 4-b

    • B. 

      1-a, 2-b, 3-d, 4-c

    • C. 

      1-c, 2-d, 3-b, 4-a

    • D. 

      1-b, 2-a, 3-c, 4-d

  • 20. 
    Microscopy of the bulbs of Urgenia indica family Liliaceae shows:
    • A. 

      Prism of calcium oxalate

    • B. 

      Calcium carbonate and silica

    • C. 

      Rosetters of calcium oxalate

    • D. 

      Rhaphides of calcium oxalate

  • 21. 
    What term is used to indicate the ability of a cancer to invade other parts of the body and to produce secondary tumours?
    • A. 

      Carcinogenesis

    • B. 

      Apoptosis

    • C. 

      Metastasis

    • D. 

      Mutagenesis

  • 22. 
    Which molecules are involved in the anchoring of cells to an extracellular matrix?
    • A. 

      Integrins

    • B. 

      Interleukins

    • C. 

      Angiostatin

    • D. 

      Cyclins

  • 23. 
    Which of the following statements is false with respect to an enzyme's ability to catalyse a reaction?
    • A. 

      An enzyme provides a reaction surface and a suitable environment for the reaction to take place

    • B. 

      An enzyme binds reactants such that they are positioned correctly and can attain their transition-state configurations

    • C. 

      An enzyme allows the reaction to go through a less stable transition state than would normally be the case

    • D. 

      An enzyme can weaken bonds in reactants through the binding process

  • 24. 
    Which of the following statements is not true regarding the active site of an enzyme?
    • A. 

      An active site is normally a hollow or cleft on the surface of an enzyme.

    • B. 

      An active site is normally hydrophilic in nature.

    • C. 

      Substrates fit into active sites and bind to functional groups within the active site.

    • D. 

      An active site contains amino acids which are important to the binding process and the catalytic mechanism.

  • 25. 
    Which of the following statements best describes an allosteric binding site?
    • A. 

      It is a binding site containing amino acids with aliphatic side chains.

    • B. 

      It is a binding site that can accept a wide variety of differently shaped molecules.

    • C. 

      It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.

    • D. 

      It is a description of an active site which has undergone an induced fit.