Mpharm-cet Test No.1

50 Questions | By Pharmacareer2015 | Updated: Mar 20, 2022 | Attempts: 269

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MPHARM-CET TEST NO. 1Designed by Dr. Anwar R. ShaikhCourtesy:1) Dr. Aman B. Upaganlawar (M. Pharm,PhD,MAMS)Associate Professor, Department of Pharmacology. SNJBs SSDJ College of Pharmacy,Neminagar,Chandwad. Dist:Nashik:423 1012) Mr. C V PanchalAsst. ProfessorDept. Of Pharmacognosy,Maharashtra College of Pharmacy,Nilanga, Dist. Latur, PIN-413521

Questions and Answers

1.

Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of flux?
- A.
  
  Ondansetron
- B.
  
  Metaclopramide
- C.
  
  Sodium citrate
- D.
  
  Atropine
2.

All of the following hormones have cell surface receptors except
- A.
  
  Adrenaline
- B.
  
  Growth Hormone
- C.
  
  Insulin
- D.
  
  Thyroxin
3.

A highly ionized drug
- A.
  
  Is excreted mainly by the kidney
- B.
  
  Can cross the placental barrier easily
- C.
  
  Is well absorbed from the intestine
- D.
  
  Accumulates in the cellular lipids
4.

Which one of the following is true of adrenal suppression due to steroid therapy?
- A.
  
  It is not associated with atrophy of adrenal glands
- B.
  
  It does not occur in patients receiving inhaled steroids
- C.
  
  It should be expected in anyone receiving greater than 5mg of prednisolone daily
- D.
  
  Following cessation, the stress response normalizes after 8 weeks
5.

With which of the following theophylline has an antagonistic interaction?
- A.
  
  Histamine receptors
- B.
  
  Bradykinin receptors
- C.
  
  Adenosine receptors
- D.
  
  Imidazoline receptors
6.

Which one of the following drugs increases gastrointestinal motility?
- A.
  
  Glycopyrrolate
- B.
  
  Atropine
- C.
  
  Neostigmine
- D.
  
  Fentanyl
7.

Which one of the following drugs has been shown to offer protection from gastric aspiration syndrome in a patient with symptoms of flux?
- A.
  
  Ondansetron
- B.
  
  Metaclopramide
- C.
  
  Sodium citrate
- D.
  
  Atropine
8.

Inverse agonist of benzodiazepine receptor is
- A.
  
  Phenobarbitone
- B.
  
  Flumazenil
- C.
  
  Beta-carboline
- D.
  
  Gabapentin
9.
1. At the end of phase III clinical trial the drug will be submitted to the relevant regulatory authority for:
- A.
  
  Licensing
- B.
  
  Evaluation
- C.
  
  Post Marketing studies
- D.
  
  All of above
10.

Rectal administration of drugs:
- A.
  
  Gives predictable blood levels
- B.
  
  From lower 1/3rd avoids first pass & upper 2/3rds doesn’t
- C.
  
  None undergoes first pass metabolism
- D.
  
  All of it undergoes first pass metabolism
11.

Different species of Ephedra can be identified by observing the nature of
- A.
  
  Inner surface
- B.
  
  Outer surface
- C.
  
  Trichomes
- D.
  
  Scaly Leaves
12.

Indian Rhubarb can be distinguished from Rhapontic Rhubarb by the flurorescence it emits under UV light, Indian Rhubarb gives:
- A.
  
  Deep yellow
- B.
  
  Deep Violate
- C.
  
  Orange
- D.
  
  Pale Green
13.

Genetically modified species of papaver namely papaver bracetum and papver oriental contain the predominant alkaloid:
- A.
  
  Morphine
- B.
  
  Codeine
- C.
  
  Thebaine
- D.
  
  Narcotine
14.

A substance used for the modification of silica gel for reversed phase TLC is:
- A.
  
  Benzene
- B.
  
  Glycerine
- C.
  
  Silicone Oil
- D.
  
  Ether
15.

Klunge's Test is for the identification of:
- A.
  
  Barbaloin
- B.
  
  Isobarbaloin
- C.
  
  Alionosides
- D.
  
  Aleosin
16.

Microscopic character of Ginger Rhizome are:
- A.
  
  Spindle shaped lignified fibers and sclerides
- B.
  
  Cluster crystals of calcium oxalate and sclerides
- C.
  
  Non lignified vessels and sac shaped starch grains
- D.
  
  Non lignified vessels and sclerides
17.

A transeverse section of the root of Glycerrhiza glabra when treated with 80% Sulphuric acid gives:
- A.
  
  Deep yellow colour
- B.
  
  No reaction but only charring
- C.
  
  Deep blue colour
- D.
  
  Deep red colour
18.

A naturally occuring amino acid which does not have a chiral centre is :
- A.
  
  Glycine
- B.
  
  Alanine
- C.
  
  Tryptophane
- D.
  
  Tyrosine
19.

Match Group I with II:Group I Group II1. Gentisin a. Flavonol2. Genistein b. Flavone3. Apigenin c. Xanthone4. Quercetin d. Isoflavone
- A.
  
  1-d, 2-c, 3-a, 4-b
- B.
  
  1-a, 2-b, 3-d, 4-c
- C.
  
  1-c, 2-d, 3-b, 4-a
- D.
  
  1-b, 2-a, 3-c, 4-d
20.

Microscopy of the bulbs of Urgenia indica family Liliaceae shows:
- A.
  
  Prism of calcium oxalate
- B.
  
  Calcium carbonate and silica
- C.
  
  Rosetters of calcium oxalate
- D.
  
  Rhaphides of calcium oxalate
21.

What term is used to indicate the ability of a cancer to invade other parts of the body and to produce secondary tumours?
- A.
  
  Carcinogenesis
- B.
  
  Apoptosis
- C.
  
  Metastasis
- D.
  
  Mutagenesis
22.

Which molecules are involved in the anchoring of cells to an extracellular matrix?
- A.
  
  Integrins
- B.
  
  Interleukins
- C.
  
  Angiostatin
- D.
  
  Cyclins
23.

Which of the following statements is false with respect to an enzyme's ability to catalyse a reaction?
- A.
  
  An enzyme provides a reaction surface and a suitable environment for the reaction to take place
- B.
  
  An enzyme binds reactants such that they are positioned correctly and can attain their transition-state configurations
- C.
  
  An enzyme allows the reaction to go through a less stable transition state than would normally be the case
- D.
  
  An enzyme can weaken bonds in reactants through the binding process
24.

Which of the following statements is not true regarding the active site of an enzyme?
- A.
  
  An active site is normally a hollow or cleft on the surface of an enzyme.
- B.
  
  An active site is normally hydrophilic in nature.
- C.
  
  Substrates fit into active sites and bind to functional groups within the active site.
- D.
  
  An active site contains amino acids which are important to the binding process and the catalytic mechanism.
25.

Which of the following statements best describes an allosteric binding site?
- A.
  
  It is a binding site containing amino acids with aliphatic side chains.
- B.
  
  It is a binding site that can accept a wide variety of differently shaped molecules.
- C.
  
  It is a binding site, which is separate from the active site, and affects the activity of an enzyme when it is occupied by a ligand.
- D.
  
  It is a description of an active site which has undergone an induced fit.