This quiz on Beta-Lactam Antibiotics assesses knowledge on their mechanisms, clinical applications, and specific patient management scenarios. It is designed to enhance understanding of antibiotic treatment strategies in various medical conditions, pivotal for healthcare professionals.
Amoxicillin
Cephalexin
Ceftriaxone plus vancomycin
Nafcillin
Piperacillin
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Beta-lactamases
Cell membrane synthesis
N-acetylmuramic acid synthesis
Peptidoglycan cross-linking
Transglycosylation
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Administer a single oral dose of fosfomycin
Give no other antibiotics because drug treatment of gonorrhea provides coverage for incubating syphilis
Inject intramuscular benzathine penicillin G
Treat with oral tetracycline for 7 d
Treat with vancomycin
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Aztreonam
Ceftriaxone
Meropenem
Oxacillin
Ticarcillin plus clavulanic acid
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A single intramuscular dose of ceftriaxone
Amoxicillin orally for 7 d
Procaine penicillin G intramuscularly as a single dose plus oral probenecid
Meropenem orally for 7 d
Vancomycin intramuscularly as a single dose
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Alterations in porin structure
Beta-lactamase production
Changes in chemical structure of target penicillin-binding proteins
Changes in the d-Ala-d-Ala building block of peptidoglycan precursor
Decreased intracellular accumulation of penicillin G
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Ampicillin
Cefoxitin
Fosfomycin
Vancomycin
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Amoxicillin-clavulanate
Aztreonam
Ceftriaxone
Ticarcillin
Vancomycin
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Cephalexin and other first-generation cephalosporins do not cross the blood-brain barrier
Ceftriaxone and nafcillin are both eliminated mainly via biliary secretion
Instability of penicillins in gastric acid can limit their oral absorption
Renal tubular reabsorption of amoxicillin is inhibited by probenecid
Ticarcillin has activity against several gram-negative rods
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