Cytology: Kidney Function And Tests
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Questions and Answers
- 1.
The kidneys _____ water and electrolytes in times of a negative balance.
- A.
Increase
- B.
Decrease
- C.
Absorb
- D.
Conserve
Correct Answer
D. ConserveExplanation
The kidneys have the ability to conserve water and electrolytes when the body is experiencing a negative balance. This means that they can reduce the amount of water and electrolytes that are excreted in urine, helping to retain these essential substances within the body. This conservation mechanism is important for maintaining proper hydration and electrolyte balance, especially in situations where there may be a limited supply of water or excessive loss of fluids, such as during dehydration or excessive sweating.Rate this question:
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- 2.
The kidneys decrease water and electrolyte elimination in times of a positive balance.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
They increase elimination.Rate this question:
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- 3.
The kidneys excrete or conserve _______ ions to maintain blood pH within normal limits.
- A.
Potassium
- B.
Hydrogen
- C.
Sodium
- D.
Phosphate
Correct Answer
B. HydrogenExplanation
The kidneys play a crucial role in maintaining the body's acid-base balance. They excrete or conserve hydrogen ions to regulate blood pH within normal limits. Hydrogen ions are involved in the acidity of a solution, and the kidneys help remove excess hydrogen ions when blood pH is too low (acidic) or conserve them when blood pH is too high (alkaline). This process helps maintain the body's overall pH balance and ensures proper functioning of various physiological processes.Rate this question:
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- 4.
Renin is an enzyme that....
- A.
Helps control blood pressure
- B.
Helps control thermoregulation
- C.
Helps control urine elimination
- D.
Helps control RBC production
Correct Answer
A. Helps control blood pressureExplanation
Renin is an enzyme that plays a crucial role in regulating blood pressure. It is released by special cells in the kidneys when there is a decrease in blood volume or low blood pressure. Renin acts on a protein called angiotensinogen, converting it into angiotensin I. This further gets converted into angiotensin II, a potent vasoconstrictor that raises blood pressure. Angiotensin II also stimulates the release of aldosterone, which leads to increased sodium and water reabsorption, further elevating blood pressure. Therefore, renin's primary function is to help control blood pressure.Rate this question:
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- 5.
The kidneys produce ________, a hormone necessary for RBC production.
- A.
ACTH
- B.
Renin
- C.
Erythropoeitin
- D.
Angiotensin
Correct Answer
C. ErythropoeitinExplanation
The kidneys produce erythropoietin, a hormone necessary for red blood cell (RBC) production. Erythropoietin stimulates the bone marrow to produce more red blood cells, which are responsible for carrying oxygen throughout the body. Without erythropoietin, the body would not be able to maintain a sufficient level of RBCs, leading to anemia and other complications.Rate this question:
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- 6.
_______ are fatty acids used to stimulate contractility of uterine and smooth muscle, lower blood pressure, regulate acid secretions, regulate temperature and platelet aggregation, and control inflammation.
- A.
Triglycerides
- B.
Prostaglandins
- C.
Angiotensins
- D.
Booh.
Correct Answer
B. ProstaglandinsExplanation
Prostaglandins are fatty acids that have various important functions in the body. They are involved in stimulating the contraction of uterine and smooth muscles, which is important during childbirth. They also help in regulating blood pressure, acid secretions, body temperature, and platelet aggregation. Additionally, prostaglandins play a role in controlling inflammation, which is a crucial part of the body's immune response. Therefore, prostaglandins are the correct answer for this question.Rate this question:
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- 7.
Kidneys aid in vitamin D activation and maintain homeostasis.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
The statement is true because kidneys play a crucial role in activating vitamin D, which is necessary for the absorption of calcium and phosphorus in the intestines. Additionally, kidneys help maintain homeostasis by regulating the balance of electrolytes, fluids, and pH levels in the body.Rate this question:
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- 8.
Kidneys receive blood from the _______ .
- A.
Caudal vena cava
- B.
Renal veins
- C.
Renal arteries
- D.
Cranial vena cava
Correct Answer
A. Caudal vena cavaExplanation
The kidneys receive blood from the caudal vena cava. The caudal vena cava is a large vein that carries deoxygenated blood from the lower body back to the heart. The renal veins, on the other hand, carry oxygenated blood from the kidneys back to the heart. The renal arteries, on the other hand, supply oxygenated blood to the kidneys. The cranial vena cava carries deoxygenated blood from the upper body to the heart. Therefore, the correct answer is the caudal vena cava, as it is the vein that delivers blood to the kidneys.Rate this question:
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- 9.
Blood enters the ____ of the ____ where nearly all water and small dissolved solutes pass into the collecting tubules.
- A.
Nephron, glomerulus
- B.
Glomerulus, renal cortex
- C.
Glomerulus, renal medulla
- D.
Glomerulus, nephron
Correct Answer
D. Glomerulus, nephronExplanation
The glomerulus is the part of the nephron where blood enters. It is a network of capillaries located in the renal cortex. From the glomerulus, water and small dissolved solutes pass into the collecting tubules, which are also part of the nephron. Therefore, the correct answer is "Glomerulus, nephron."Rate this question:
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- 10.
Each nephron contains secretions that function to ______ or ______ specific solutes.
- A.
Filter, secrete
- B.
Secrete, collect
- C.
Reabsorb, secrete
- D.
Filter, reabsorb
Correct Answer
C. Reabsorb, secreteExplanation
Tomayto, tomahto.Rate this question:
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- 11.
Resorption of glucose occurs in the ________.
- A.
Collection duct
- B.
Distal convoluted tubule
- C.
Loop of Henle
- D.
Proximal convoluted tubule
Correct Answer
D. Proximal convoluted tubuleExplanation
The proximal convoluted tubule is responsible for the resorption of glucose. This tubule is located in the nephron of the kidney and plays a crucial role in reabsorbing important molecules, such as glucose, from the filtrate back into the bloodstream. The resorption of glucose in the proximal convoluted tubule is facilitated by specialized transport proteins, such as sodium-glucose cotransporters, which actively transport glucose across the tubule epithelium. This process helps to maintain glucose homeostasis in the body by preventing excessive glucose loss in the urine.Rate this question:
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- 12.
Mineral salts secretion and reabsorption occurs in the descending loop of Henle and the distal convoluted tubule.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
The ASCENDING loop of Henle and distal convoluted tubule.Rate this question:
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- 13.
A nephron has a specific resorptive capability for each substance called _____
- A.
Maximum capacity
- B.
Substance limit
- C.
System overload
- D.
Renal threshold
Correct Answer
D. Renal thresholdExplanation
The correct answer is "Renal threshold." The renal threshold refers to the maximum concentration of a substance that can be resorbed by the nephron. Once this threshold is reached, any excess of the substance will not be reabsorbed and will be excreted in the urine. This threshold varies for different substances and helps maintain the balance of electrolytes and other substances in the body.Rate this question:
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- 14.
The volume excreted from the kidneys is less than 1% of the volume that originally entered.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Because most water is reabsorbed.Rate this question:
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- 15.
Blood returns from the kidneys to the rest of the body via the.......
- A.
Renal veins
- B.
Hiiiiighway to heeeeelllll
- C.
Renal arteries
- D.
Caudal vena cava
Correct Answer
D. Caudal vena cavaExplanation
The correct answer is the Caudal vena cava. The caudal vena cava is a large vein that carries deoxygenated blood from the lower body and organs, including the kidneys, back to the heart. It receives blood from the renal veins, which drain the kidneys, and then transports it to the right atrium of the heart.Rate this question:
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- 16.
BUN: Assesses the glomerular ______.
- A.
Collection rate
- B.
Resorption rate
- C.
Filtration rate
- D.
Elimination rate
Correct Answer
C. Filtration rateExplanation
The correct answer is "Filtration rate." BUN (Blood Urea Nitrogen) is a test used to assess kidney function. It measures the amount of nitrogen in the blood that comes from urea, a waste product produced by the liver. The BUN test indirectly reflects the filtration rate of the glomeruli in the kidneys, as the glomeruli filter waste products from the blood. Therefore, the BUN test helps assess the filtration rate of the glomeruli in the kidneys.Rate this question:
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- 17.
Urea is the end product of protein breakdown.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Amino acid breakdown. (which is kinda funny cuz that's what proteins are made of)Rate this question:
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- 18.
BUN levels help determine the ability of the kidney to remove _______ from the blood
- A.
Old cells
- B.
Nutrient waste
- C.
Nitrogenous waste
- D.
Phosphate waste
Correct Answer
C. Nitrogenous wasteExplanation
BUN levels help determine the ability of the kidney to remove nitrogenous waste from the blood. Nitrogenous waste is produced by the breakdown of proteins in the body. The kidneys filter the blood and remove waste products, including nitrogenous waste, which is then excreted in urine. Monitoring BUN levels can provide information about how well the kidneys are functioning and their ability to eliminate waste from the body.Rate this question:
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- 19.
In healthy patients, all urea passes through the glomerulus and enters the renal tubules.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
That bird though.Rate this question:
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- 20.
How much of the urea is reabsorbed before excreting the remainder?
- A.
1/4
- B.
1/3
- C.
What are you talking about. All of it is excreted.
- D.
1/2
Correct Answer
D. 1/2Explanation
Half of the urea is reabsorbed before excreting the remainder. This means that only half of the urea that is filtered by the kidneys is actually excreted in the urine, while the other half is reabsorbed back into the bloodstream.Rate this question:
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- 21.
Increased BUN could mean thaaaaaat.....
- A.
Too much urea was excreted
- B.
Too little urea was excreted
- C.
The glomerulus is holding all the urea hostage
- D.
The patient is dehydrated
Correct Answer
B. Too little urea was excretedExplanation
An increased BUN (blood urea nitrogen) level suggests that too little urea was excreted. Urea is a waste product that is formed when proteins are broken down in the liver. It is then filtered by the kidneys and excreted in the urine. If there is a decrease in the excretion of urea, it can lead to an accumulation of urea in the blood, resulting in an increased BUN level. This could be due to kidney dysfunction or other factors affecting the excretion of urea.Rate this question:
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- 22.
Urea must be execreted in low volumes of water.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
High volumes. Had enough of urea yet?Rate this question:
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- 23.
Check all the nonrenal causes of increased BUN
- A.
Nigh protein diet
- B.
Urea and the patient like each other ( a lot)
- C.
Fever
- D.
NSAIDS
- E.
Corticosteroids
Correct Answer(s)
A. Nigh protein diet
C. Fever
E. CorticosteroidsExplanation
The correct answer is Nigh protein diet, Fever, Corticosteroids. A high protein diet can increase the levels of urea in the body, leading to increased BUN levels. Fever can also cause increased BUN levels as it increases protein breakdown. Corticosteroids can affect protein metabolism and increase BUN levels as well.Rate this question:
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- 24.
Check the causes of BUN increase.
- A.
Anorexia
- B.
Prerenal factors such as shock and dehydration
- C.
Postrenal factors such as obstruction
- D.
Liver disease
Correct Answer(s)
B. Prerenal factors such as shock and dehydration
C. Postrenal factors such as obstructionExplanation
The correct answer is prerenal factors such as shock and dehydration, and postrenal factors such as obstruction. Prerenal factors refer to conditions that occur before the kidneys, such as shock and dehydration, which can lead to decreased blood flow to the kidneys and impaired kidney function. This can cause an increase in blood urea nitrogen (BUN) levels. Postrenal factors, on the other hand, occur after the kidneys, such as obstruction, which can prevent the normal flow of urine and cause a buildup of waste products in the blood, including BUN. Both prerenal and postrenal factors can contribute to an increase in BUN levels.Rate this question:
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- 25.
Check the causes of decreased BUN
- A.
Shock and dehydration
- B.
Anorexia
- C.
Azotemia
- D.
Liver disease
- E.
Kidney disease
- F.
Tubular injury
Correct Answer(s)
B. Anorexia
D. Liver disease
F. Tubular injuryExplanation
The correct answer includes anorexia, liver disease, and tubular injury as causes of decreased BUN. Anorexia, or loss of appetite, can lead to decreased protein intake and subsequently lower BUN levels. Liver disease can impair the liver's ability to produce urea, resulting in decreased BUN. Tubular injury, which affects the renal tubules in the kidneys, can also lead to decreased BUN levels as it impairs the reabsorption of urea. These conditions can all contribute to a decrease in BUN levels.Rate this question:
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- 26.
Creatinine diffuses out of the ____ cell and into most body fluids.
- A.
Oh yay no more urea!
- B.
Muscle
- C.
Cardiac
- D.
Renal
Correct Answer
B. MuscleExplanation
Creatinine is a waste product that is produced in the muscles as a result of normal muscle metabolism. It is then released into the bloodstream and eventually filtered out by the kidneys to be excreted in urine. Therefore, creatinine diffuses out of the muscle cells and into most body fluids.Rate this question:
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- 27.
If physical activity remains constant, the amount of creatine metabolized to creatinine remains constant.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
What does this even mean....Rate this question:
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- 28.
All serum creat is filtered through the ____ and eliminated in the ____.
- A.
Liver, kidney
- B.
Glomeruli, urine
- C.
Renal tubules, urine
- D.
Renal medulla, urine
Correct Answer
B. Glomeruli, urineExplanation
Serum creatinine is a waste product of muscle metabolism and is filtered by the glomeruli in the kidneys. The glomeruli act as a filtration system, allowing waste products like creatinine to pass through while retaining necessary substances in the bloodstream. After filtration, the creatinine is eliminated from the body through urine. Therefore, the correct answer is "Glomeruli, urine."Rate this question:
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- 29.
A decrease in Glomerular Filtration Rate (GFR) results in ______ serum _____ .
- A.
Decreased, creat
- B.
Decreased, urea
- C.
Increased, urea
- D.
Increased, creat
Correct Answer
D. Increased, creatExplanation
A decrease in Glomerular Filtration Rate (GFR) means that less blood is being filtered by the kidneys, resulting in a reduced ability to remove waste products from the body. Creatinine is a waste product produced by muscles that is normally filtered out by the kidneys. Therefore, a decrease in GFR would lead to an accumulation of creatinine in the blood, resulting in increased serum creatinine levels.Rate this question:
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- 30.
Check the things that influence serum creat concentration.
- A.
Fluid and hydration levels
- B.
Urea levels
- C.
Prerenal factors (shock)
- D.
Postrenal factors (urethral and bladder obstruction)
- E.
Liver disease
Correct Answer(s)
A. Fluid and hydration levels
C. Prerenal factors (shock)
D. Postrenal factors (urethral and bladder obstruction)Explanation
The correct answer includes factors that can influence serum creatinine concentration. Fluid and hydration levels can affect the concentration of creatinine in the blood. Prerenal factors such as shock can also impact serum creatinine levels. Additionally, postrenal factors like urethral and bladder obstruction can affect the concentration of creatinine in the blood. However, the answer does not include urea levels or liver disease as factors that influence serum creatinine concentration.Rate this question:
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- 31.
Hemolysis doesn't influence creat test results.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
Mind blown.Rate this question:
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- 32.
A disproportionate decrease in BUN as compared to creat could indicate dehydration.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Increase.Rate this question:
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- 33.
GFR can be decreased as much as ____ times the normal rate before changes are seen in the BUN or creat.
- A.
5
- B.
2
- C.
3
- D.
4
Correct Answer
D. 4 -
- 34.
Urine Protein Creat Ratio (UPC): Performed on samples that show excess ___.
- A.
Urea
- B.
Protein
- C.
Glucose
- D.
ALT
Correct Answer
B. ProteinExplanation
The Urine Protein Creatinine Ratio (UPC) test is performed on samples that show excess protein. This test measures the ratio of protein to creatinine in the urine, which helps in evaluating kidney function and detecting kidney diseases. High levels of protein in the urine can indicate conditions such as kidney damage, inflammation, or infection. Therefore, the correct answer is protein.Rate this question:
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- 35.
UPC determines the amount of protein in the urine.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
The amount of protein LOST in the urine.Rate this question:
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- 36.
For UPC, collect ___ of mid-day urine.
- A.
4-6 mL
- B.
5-10 mL
- C.
4-5 mL
- D.
5-6 mL
Correct Answer
B. 5-10 mLExplanation
The correct answer is 5-10 mL. This is the recommended amount of mid-day urine to collect for a UPC (urine protein-to-creatinine) test. This test is used to measure the amount of protein in the urine and is often used to diagnose and monitor kidney conditions. Collecting 5-10 mL of mid-day urine provides a sufficient sample size for accurate testing.Rate this question:
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- 37.
After centrifuging the urine sample, the supernatant is used to determine the UPC.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
After centrifuging the urine sample, the supernatant is used to determine the UPC. This means that the solid particles in the urine sample are separated from the liquid portion by centrifugation. The liquid portion, known as the supernatant, is then analyzed to determine the urine protein-to-creatinine ratio (UPC). This ratio is an important indicator of kidney function and can help diagnose and monitor conditions such as kidney disease. Therefore, the statement is true.Rate this question:
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- 38.
A healthy patient will have the following results.
- A.
UP:UC >0.5
- B.
UP:UC 0.5-1.0
- C.
UP:UC
- D.
UP:UC >2
Correct Answer
C. UP:UCExplanation
The UP:UC ratio is a measure of the concentration of urine protein to urine creatinine. A healthy patient will have a UP:UC ratio greater than 0.5, indicating a normal level of protein in the urine relative to creatinine. A ratio of 0.5-1.0 is also considered normal. A ratio of UP:UC >2 would indicate a higher level of protein in the urine, which may be a sign of kidney damage or other underlying health conditions.Rate this question:
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- 39.
UP:UC > 0.5 = Azotemia.
- A.
True
- B.
False
Correct Answer
A. TrueExplanation
If the ratio of urinary protein (UP) to urinary creatinine (UC) is greater than 0.5, it indicates azotemia. Azotemia is a condition characterized by an increased level of nitrogenous waste products in the blood, such as urea and creatinine. Therefore, the statement "UP:UC > 0.5 = Azotemia" is true.Rate this question:
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- 40.
UP:UC >2 is normal.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Glomerular proteinuriaRate this question:
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- 41.
UP:UC 0.5-1.0 = ?
- A.
Healthy
- B.
Azotemia
- C.
Glomerular proteinuria
- D.
Suspicious and must be monitored
Correct Answer
D. Suspicious and must be monitoredExplanation
The given answer "Suspicious and must be monitored" suggests that the value of UP:UC 0.5-1.0 falls within a range that is considered suspicious and requires monitoring. This could indicate a potential abnormality or dysfunction in the urinary system. However, without further context or information, it is difficult to determine the specific condition or significance of this finding.Rate this question:
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- 42.
Which of the following is pre-renal in the classification of azotemia?
- A.
Increased BUN +/- creat
- B.
Loss of at least 2/3 of the functional nephrons
- C.
Obstruction, tear in ureter, bladder, urethra
- D.
Hypovolemia due to blood loss, dehydration, hypotension, shock, cardio disease, decreased renal blood flow
Correct Answer
D. Hypovolemia due to blood loss, dehydration, hypotension, shock, cardio disease, decreased renal blood flowExplanation
Hypovolemia due to blood loss, dehydration, hypotension, shock, cardio disease, decreased renal blood flow is classified as pre-renal in the classification of azotemia because it refers to conditions that occur before the kidneys and affect the blood flow to the kidneys. These conditions lead to decreased perfusion and oxygenation of the kidneys, resulting in reduced filtration and excretion of waste products. This can cause an increase in blood urea nitrogen (BUN) and creatinine levels, which are indicative of azotemia.Rate this question:
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- 43.
In the classification of azotemia, the loss of at least 2/3 of the functional nephrons is post-renal.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Renal. Within the kidneys.Rate this question:
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- 44.
Check the clincal signs of renal failure
- A.
Anorexia, vomiting, weight lost
- B.
Hypotension
- C.
PU/PD, nocturia, constipation, diarrhea
- D.
Lethargy
- E.
Acute blindness due to hypertension
- F.
Hematuria
- G.
Proteinuria
- H.
Anemia
- I.
Dehydration
- J.
Cachexia
- K.
Fruity urine odor
- L.
Oral ulcers
- M.
Uremia breath
Correct Answer(s)
A. Anorexia, vomiting, weight lost
C. PU/PD, nocturia, constipation, diarrhea
D. Lethargy
E. Acute blindness due to hypertension
H. Anemia
I. Dehydration
J. Cachexia
L. Oral ulcersExplanation
The correct answer includes a comprehensive list of clinical signs of renal failure. These signs can help identify the presence of renal failure in a patient. Anorexia, vomiting, weight loss, PU/PD (polyuria/polydipsia), nocturia, constipation, diarrhea, lethargy, acute blindness due to hypertension, anemia, dehydration, cachexia, oral ulcers are all potential signs of renal failure. These signs may vary in severity and can occur in combination or individually. The presence of these signs can indicate the need for further evaluation and treatment for renal failure.Rate this question:
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Mar 22, 2023Quiz Edited by
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