Inflammation And Repair Quiz: MCQ Trivia!

2.

What is a special form of chronic inflammation that typically is not preceded by an acute, PMN-mediated inflammation?

Purulent inflammation
Ulcerative inflammation
Psuedomembranous inflammation
Granulomatous inflammation

Correct Answer

A. Granulomatous inflammation

Explanation

Granulomatous inflammation is a special form of chronic inflammation that typically does not have an acute, PMN-mediated inflammation preceding it. It is characterized by the formation of granulomas, which are collections of immune cells, such as macrophages and lymphocytes, that form in response to persistent or indigestible substances. These granulomas can be seen in various diseases, such as tuberculosis, sarcoidosis, and Crohn's disease.

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3.

Tuberculosis is a granulomatous disease, as are certain fungal diseases.

True
False

Correct Answer

A. True

Explanation

Tuberculosis is classified as a granulomatous disease because it is characterized by the formation of granulomas in the affected tissues. Granulomas are small nodules that form as a result of the immune system's response to the presence of certain pathogens, such as the bacteria that cause tuberculosis. Similarly, certain fungal diseases can also lead to the formation of granulomas in the body. Therefore, the statement that tuberculosis is a granulomatous disease, as are certain fungal diseases, is true.

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4.

Granulomatous reactions are mediated by macrophages and T-lymphocytes that accumulate at the site of injury, forming nodules.

True
False

Correct Answer

A. True

Explanation

Granulomatous reactions are characterized by the accumulation of macrophages and T-lymphocytes at the site of injury, resulting in the formation of nodules. These nodules are composed of immune cells that are involved in the immune response against certain pathogens or foreign substances. The presence of macrophages and T-lymphocytes in granulomas suggests an ongoing immune response and inflammation at the site of injury. Therefore, the statement that granulomatous reactions are mediated by macrophages and T-lymphocytes that accumulate at the site of injury, forming nodules, is true.

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5.

Epithelioid cells are motile and phagocytic.

True
False

Correct Answer

A. False

Explanation

Macrophages are motile and phagocytic, epithelioid cells are immobile and produce secretory products that act as mediators of inflammation.

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6.

In what type of inflammation of epithelioid cells fuse to form multi-nucleated giant cells found on the rim of the granulomas?

Purulent inflammation
Ulcerative inflammation
Caseating inflammation
Granulomatous inflammation
Casserole inflammation

Correct Answer

A. Granulomatous inflammation

Explanation

Granulomatous inflammation is a type of inflammation where epithelioid cells fuse together to form multi-nucleated giant cells on the rim of the granulomas. This type of inflammation is characterized by the formation of granulomas, which are small nodular structures consisting of immune cells such as macrophages. These giant cells are typically found in response to persistent infections or foreign bodies that the body is unable to eliminate. They help to contain the infectious agent or foreign material and prevent its spread.

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7.

Granulomas destroy tissue and tend to persist for a long time.

True
False

Correct Answer

A. True

Explanation

Granulomas are immune system responses that form when the body is unable to eliminate harmful substances, such as bacteria or foreign objects. These structures are made up of immune cells and can cause tissue damage as they attempt to contain and eliminate the threat. Granulomas are known to persist for a long time, as they are often unable to completely eliminate the underlying cause. Therefore, the statement that granulomas destroy tissue and tend to persist for a long time is true.

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8.

Give examples of granulomatous inflammation.

TB, chonic cervicitis, and colitis
Duodenal ulcer and histoplasma
Pericarditis, TB, and peritonitis
TB, syphilis, and leprosy
Tuna noodle casserole and tuberculosis

Correct Answer

A. TB, syphilis, and leprosy

Explanation

Granulomatous inflammation refers to a specific type of chronic inflammation characterized by the formation of granulomas, which are collections of immune cells. Tuberculosis (TB), syphilis, and leprosy are all examples of diseases that can cause granulomatous inflammation. In these diseases, the immune system forms granulomas in response to the presence of the causative organisms. Granulomas help to contain the infection and prevent its spread, but they can also lead to tissue damage and scarring. Therefore, TB, syphilis, and leprosy are appropriate examples of granulomatous inflammation.

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9.

In angiogenesis ,which comes fourth:

Increased vascular permeability and oedema formation.
Proteolysis of extracellular matrix
Blood vessel lumen formation
Proliferation of vascular endothelial cells
Migration and chemotaxis of vascular endothelial cells

Correct Answer

A. Blood vessel lumen formation

Explanation

Blood vessel lumen formation is the fourth step in angiogenesis. Angiogenesis is the process of forming new blood vessels from pre-existing ones. The first step is the proliferation of vascular endothelial cells, followed by their migration and chemotaxis. The next step is the proteolysis of the extracellular matrix, which allows the endothelial cells to create a path for the new blood vessel. Finally, blood vessel lumen formation occurs, where the endothelial cells organize themselves into a tube-like structure to form the lumen of the blood vessel.

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10.

More wound contraction is required in

Incised wound
Excised wound
Both
Neither

Correct Answer

A. Excised wound

Explanation

In an excised wound, the edges of the wound are completely removed, leaving a clean surgical incision. This type of wound requires more wound contraction because there is a larger gap between the edges of the wound that needs to be closed. Wound contraction is the process by which the edges of the wound come together and close, reducing the size of the wound. In contrast, an incised wound is a clean, straight cut that typically does not require as much wound contraction because the edges of the wound are already close together. Therefore, the correct answer is excised wound.

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11.

The following could complicate wound healing except:

Wound rupture.
Epidermoid cyst.
Incisional hernia.
Dermoid cyst
Malignant change.

Correct Answer

A. Dermoid cyst

Explanation

A dermoid cyst is a benign tumor that typically contains a variety of cell types, such as skin cells, hair follicles, and sweat glands. It is formed during embryonic development and is usually present at birth. While a dermoid cyst can cause discomfort and may need to be surgically removed, it does not directly affect wound healing. On the other hand, wound rupture, epidermoid cysts, incisional hernias, and malignant changes can all complicate wound healing by causing infection, delayed closure, or other complications.

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12.

In healing of excised wound, there is:

Less tissue loss
Less inflammatory exudate
Less necrotic tissue to be removed
Wound contraction is not necessary
More granulation tissue is required

Correct Answer

A. More granulation tissue is required

Explanation

In the healing of an excised wound, more granulation tissue is required. Granulation tissue is formed during the proliferative phase of wound healing and is composed of new blood vessels, fibroblasts, and extracellular matrix. It fills in the wound bed and provides a scaffold for the formation of new tissue. In excised wounds, there is typically a larger area of tissue loss, which requires more granulation tissue to be formed in order to fill the wound and promote healing. Additionally, the presence of granulation tissue helps to protect the wound from infection and facilitates the remodeling phase of healing.

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13.

A 37-year-old man with AIDS is admitted to the hospital with a three-week history of chest pain and shortness of breath. An Xray film of the chest shows bilateral nodularities of the lungs. A CT guided lung biopsy is shown in the image. The multinucleated cells in the field are most likely derived from which of the inflammatory cells?

Basophils
Capillary endothelial cells
Macrophages
Myofibroblasts

Correct Answer

A. Macrophages

Explanation

The multinucleated cells seen in the CT guided lung biopsy are most likely derived from macrophages. Macrophages are immune cells that play a key role in the body's defense against infections. In the context of AIDS, where the immune system is compromised, macrophages may become activated and accumulate in the lungs in response to infection. The presence of bilateral nodularities in the lungs suggests a systemic infection, which is commonly seen in AIDS patients. Therefore, it is likely that the multinucleated cells seen in the biopsy are macrophages responding to the infection.

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INFLammation And Repair Quiz: MCQ Trivia!

Tuberculoma (TB Abscess) is a type of purulent inflammation.

Quiz Preview

What is a special form of chronic inflammation that typically is not preceded by an acute, PMN-mediated inflammation?

Tuberculosis is a granulomatous disease, as are certain fungal diseases.

Granulomatous reactions are mediated by macrophages and T-lymphocytes that accumulate at the site of injury, forming nodules.

Epithelioid cells are motile and phagocytic.

In what type of inflammation of epithelioid cells fuse to form multi-nucleated giant cells found on the rim of the granulomas?

Granulomas destroy tissue and tend to persist for a long time.

Give examples of granulomatous inflammation.

In angiogenesis ,which comes fourth:

More wound contraction is required in

The following could complicate wound healing except:

In healing of excised wound, there is: