Histopathology Quiz Questions And Answers

10 Questions | By Undercover_giraf | Updated: May 11, 2022 | Attempts: 21803

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Test your knowledge of histopathology with this quiz that includes informative questions and answers today! Do you feel that you can pass this quiz? Histopathology is the microscopic examination of tissue to study all of the elements of the disease. Specifically, in clinical medicine, histopathology refers to the study of a biopsy or surgical specimen by a pathologist after the specimen. Try this quiz and see how much you actually know about this subject. All the best!

Questions and Answers

1.

Which is not the aim of fixation?
- A.
  
  To prevent putrefaction
- B.
  
  Remove excess water from the tissue
- C.
  
  Prevent osmotic swelling
- D.
  
  Render the tissue suitable for subsequent staining
- E.
  
  To prevent lysosomal activity
2.

Which statement about Formaldehyde is false?
- A.
  
  Most commonly used Aldehyde fixative
- B.
  
  It is a water soluble gas (sat. approx. 40%)
- C.
  
  Concentrated formaldehyde is 40%
- D.
  
  Penetrates tissue rapidly
- E.
  
  Fixes tissue rapidly
- F.
  
  The best fixative for nucleic acids
3.

Which statement about Glutaraldehyde is false?
- A.
  
  Widely used in EM
- B.
  
  Gives a better morphological picture at the EM level
- C.
  
  Cross-links less extensively than formaldehyde
- D.
  
  Diffuses into tissue very slowly
- E.
  
  Fixes tissue components rapidly
- F.
  
  Renders tissue too hard for paraffin sectioning
4.

Mercuric Chloride is restricted in use because:
- A.
  
  It's toxic
- B.
  
  Its corrosive
- C.
  
  Its a pollutant
- D.
  
  All of the above
5.

Formalin Solution (10%, unbuffered) is composed of:
- A.
  
  10ml Formaldehyde (40%) and 90ml distilled water
- B.
  
  50ml Formaldehyde (40%) and 50ml distilled water
- C.
  
  90ml Formaldehyde (10%) and 10ml distilled water
- D.
  
  90ml Formaldehyde (10%) and 10ml distilled water
6.

Which is not an Aldehyde fixative?
- A.
  
  Picric Acid
- B.
  
  Potassium Dichromate
- C.
  
  Glutaldehyde
- D.
  
  Mercuric chloride
7.

Why isn't microwave fixation suitable for large specimens (of tissues/organs)?
- A.
  
  Microwave fixation is best suited on tissue blocks 10-12mm thick
- B.
  
  The microwave radiation can damage fine tissue structures
- C.
  
  It is unable to heat the centre of the tissue/organ sufficiently w/o overheating the outside
- D.
  
  Using microwaves accelerates the rate of putrefaction
8.

Acetic acid...
- A.
  
  Is a denaturing agent
- B.
  
  Swells collagen
- C.
  
  Is a percipitating fixative
- D.
  
  Is an alcohol
- E.
  
  Is all of the above
9.

Microwave fixation fixes blocks in normal saline solution at ___°C for ___ seconds.
- A.
  
  74;60
- B.
  
  26;20
- C.
  
  62;30
- D.
  
  50;25
10.

Which is NOT an essential of good fixation?
- A.
  
  Fix it ASAP
- B.
  
  Refrigerate it if fixation isn't immediately possible
- C.
  
  Reagents are carefully made up
- D.
  
  Fixative is recycled and reused
- E.
  
  A suitable treatment follows fixation