Hdfn Quiz

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Test your Hemolytic Disease of the Fetus/Newborn knowledge


Questions and Answers
  • 1. 
    Hemolytic Disease of the Fetus/Newborn (HDFN) is also known as?
    • A. 

      Erythroblastosis fetalis

    • B. 

      Maternal fetalis

    • C. 

      Erythroblastosis fecal

    • D. 

      None of these

  • 2. 
    HDN is the destruction of the _____________ of the fetus/newborn by ___________ antibodies produced by the mother
    • A. 

      RBC's, IgG

    • B. 

      WBC's, IgG

    • C. 

      RBC's, IgM

    • D. 

      WBC's, IgG

  • 3. 
    The HDFN process can occur in approximately _________ % of all pregnancies
    • A. 

      10

    • B. 

      20

    • C. 

      30

    • D. 

      50

  • 4. 
    Such maternal antibodies can be produced by _________________?
    • A. 

      Leaking of fetal cells into the mothers circulation

    • B. 

      Previous pregnancies

    • C. 

      Alloimmunization by transfusion of foreign antigens

    • D. 

      Sometimes naturally in the second and third trimester of pregnancy

    • E. 

      All of the above

    • F. 

      None of the above

  • 5. 
    What can the mother be given as a preventative method?
    • A. 

      AHG immunization

    • B. 

      Rh immune globulin (RhIG)

    • C. 

      Nothing until after baby has been delivered

    • D. 

      None of the above

  • 6. 
    Prior to the late 1960's when post-partum injections was introduced, 95% of HDN was contributed to _____________
    • A. 

      Anti-K

    • B. 

      Anti-k

    • C. 

      Anti-D

    • D. 

      Anti-d

    • E. 

      None of the above

  • 7. 
    What is the most prevalent cause of HDN today?
    • A. 

      ABO incompatibility

    • B. 

      Rh incompatibility

    • C. 

      ABO/Rh incompatibility

    • D. 

      All of the above

    • E. 

      None of the above

  • 8. 
    Most of the time _____________ class antibodies are helpful in providing the fetus with immunity once they are born
    • A. 

      IgM

    • B. 

      IgG

    • C. 

      Both are correct

    • D. 

      Neither class has anything to do with the immunity

  • 9. 
    The third type of HDN is caused by other blood group system antigens?
    • A. 

      True

    • B. 

      False

  • 10. 
    The other blood group systems are particularly _______
    • A. 

      Anti-K

    • B. 

      Anti-k

    • C. 

      Anti-D

    • D. 

      Anti-H

    • E. 

      None of the above

  • 11. 
    The other blood group systems are alloantibodies
    • A. 

      True

    • B. 

      False

  • 12. 
    The most serious and dangerous of the clinical symptoms is _____________
    • A. 

      Erythro fetalis

    • B. 

      Hydrops fetalis

    • C. 

      Both a & b are acceptable

    • D. 

      None of the above

  • 13. 
    In HDN the ________________ are directed against the __________________ on the fetal RBC's that were inherited by the ________________________.
    • A. 

      Antigens, antibodies, mother

    • B. 

      Antigens, antibodies, father

    • C. 

      Antibodies, antigens, mother

    • D. 

      Antibodies, antigens, father

  • 14. 
    _________________ and _________________ enlarge to clear all the ruptured RBC's
    • A. 

      Spleen, liver

    • B. 

      Umbilical vein, spleen

    • C. 

      Placenta, liver

    • D. 

      None of the above

  • 15. 
    The most serious and dangerous of the clinical symptoms is _____________________ in which the ______________ accumulates fluid, and is capable of causing death of the fetus in utero
    • A. 

      Hydrops fetalis, mother

    • B. 

      Umbilical fetalis, fetus

    • C. 

      Hydrops fetalis, fetus

    • D. 

      Umbilical fetalis, mother

  • 16. 
    Some clinical manifestations of the disease other than the obvious RBC lysis include anemia, jaundice, skin and subcutaneous edema
    • A. 

      True

    • B. 

      False

  • 17. 
    Fetal ascites is fluid accumulation
    • A. 

      True

    • B. 

      False

  • 18. 
    _______________________ is A grave condition that results from passing of unconjugated bilirubin into the lipid tissues like the brain and spinal cord, causing brain damage
    • A. 

      Amniocyte

    • B. 

      Kernicterus

    • C. 

      Hyperbilirubinemia

    • D. 

      None of the above

  • 19. 
    Unconjugated bilirubin is when the fetal/newborn liver is not mature enough to conjugate the bilirubin
    • A. 

      True

    • B. 

      False

  • 20. 
    ___________ causes the most severe type of HDFN and the second most antigenic is ____________
    • A. 

      Anti-c, anti-d

    • B. 

      Anti-K, anti-d

    • C. 

      Anti-D, anti-c

    • D. 

      Anti-C, anti-k

  • 21. 
    What are the three basic types of HDN?
  • 22. 
    The risk for HDN due to Rh or other system antibodies can be diagnosed during pregnancy
    • A. 

      True

    • B. 

      False

  • 23. 
    ABO-HDN is usually diagnosed pre-delivery
    • A. 

      True

    • B. 

      False

  • 24. 
    In order for _____________________ to occur there has to be exposure of the _________ born(s) RBC to the mother
    • A. 

      Sensitization, first

    • B. 

      Sensitization, second

    • C. 

      Susceptibility, first

    • D. 

      Susceptibility, second

  • 25. 
    The influence of the Rh groups of the mother and fetus/newborn also play a role in the incidence of D-immunization
    • A. 

      True

    • B. 

      False

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