Genetics - 20 Difficult Questions

20 Questions | By Karthi_dr | Updated: Mar 22, 2022 | Attempts: 1757

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Genetics - 20 Difficult Questions - Quiz

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Questions and Answers

1.

Klenow fragment lacks
- A.
  
  5'→3' polymerase
- B.
  
  3'→5' exonuclease
- C.
  
  5'→3' exonuclease activity
- D.
  
  None
2.

Similarity between DNA polymerase and Glycogen synthase
- A.
  
  Both need a primer
- B.
  
  Both enzymes are processive in adding substrates
- C.
  
  Either of the above
- D.
  
  None
3.

Basic protein that binds to DNA in spermatid
- A.
  
  Histone
- B.
  
  Protamine
- C.
  
  Polyamine
- D.
  
  None
4.

Signal recognition particle contains
- A.
  
  28S RNA
- B.
  
  60S RNA
- C.
  
  40S RNA
- D.
  
  7S RNA
5.

Possibly more than 90% of genome is transcribed.
- A.
  
  True
- B.
  
  False
6.

Carboxy terminal domain (CTD) of RNA polymerase is phosphorylated by
- A.
  
  TFIID
- B.
  
  TFIIA
- C.
  
  TFIIB
- D.
  
  TFIIH
7.

Special transcription factors bind to
- A.
  
  TATA box
- B.
  
  Inr element
- C.
  
  DPE
- D.
  
  CAAT box
8.

Which is NOT a DNA binding domain ?(Don't worry, No marks for this question)
- A.
  
  Zinc finger
- B.
  
  Helix-turn-Helix
- C.
  
  Helix-loop-helix
- D.
  
  Basic domains
9.

Which is a template independent DNA polymerase ?
- A.
  
  Poly A polymerase
- B.
  
  CCA adding enzyme
- C.
  
  Terminal deoxynucleotidyl transferase
- D.
  
  None
10.

Sequence of an intron always starts and ends with(Don't worry, No marks for this question)
- A.
  
  GU,AG
- B.
  
  AG,GU
- C.
  
  GA,GU
- D.
  
  UG,AG
11.

RNA splicing requires ATP hydrolysis.
- A.
  
  True
- B.
  
  False
12.

Instead of poly A tail histone pre-mRNA has stem-loop structure.
- A.
  
  True
- B.
  
  False
13.

5S RNA is transcribed by
- A.
  
  RNA polymerase I
- B.
  
  RNA polymerase II
- C.
  
  RNA polymerase III
- D.
  
  All of the above
14.

Self-splicing is mediated by (No marks for this question!!!)
- A.
  
  Adenosine
- B.
  
  Guanosine
- C.
  
  Cytosine
- D.
  
  None
15.

Promoters of eukaryotic tRNA lie within the gene itself.
- A.
  
  True
- B.
  
  False
16.

Which amino acid(s) is/are coded by a single codon
- A.
  
  Tryptophan
- B.
  
  Methionine
- C.
  
  Both
- D.
  
  None
17.

ApoB48 & apoB100 production is due to
- A.
  
  Alternative splicing
- B.
  
  MRNA editing
- C.
  
  Alternative polyadenylation
- D.
  
  MRNA silencing
18.

Mirtrons are miRNAs located in introns
- A.
  
  True
- B.
  
  False
19.

All ribonucleases are ribozymes
- A.
  
  True
- B.
  
  False
20.

During translation, initiator tRNA binds to
- A.
  
  A site
- B.
  
  P site
- C.
  
  E site
- D.
  
  None