The Test Question Cellular Biology Test 1

44 Questions | Total Attempts: 477

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The Test Question Cellular Biology Test 1

A Cell is the basic membrane-bound unit that contains the fundamental molecules of life and of which all living things are composed. Do you have a good understanding on the cells within our bodies? The test question cellular biology test 1 will aid you in understanding it better. All the best!


Questions and Answers
  • 1. 
    Mitotic chromosomes were first visualized in the 1880s with the use of very simple tools: a basic light microscope and some dyes. Which of the following characteristics of mitotic chromosomes reflects how they were named? 
    • A. 

      Motion

    • B. 

      Color

    • C. 

      Shape

    • D. 

      Location

    • E. 

      Length

  • 2. 
    Which of the following chemical groups is not used to construct a DNA molecule? (two answers) 
    • A. 

      Five-carbon sugar

    • B. 

      Phosphate

    • C. 

      Nitrogen-containing base

    • D. 

      Six-carbon sugar

    • E. 

      Cyclic AMP

  • 3. 
    All functional DNA sequences inside a cell code for protein products. 
    • A. 

      True

    • B. 

      False

  • 4. 
    Gene sequences correspond exactly to the respective protein sequences produced from them.
    • A. 

      True

    • B. 

      False

  • 5. 
    The human genome has enough DNA to stretch more than 2m. However, this DNA is not contained in a single molecule; it is divided into linear segments and packaged into structures called chromosomes. What is the total number of chromosomes found in each of the somatic cells in your body? 
    • A. 

      22

    • B. 

      23

    • C. 

      44

    • D. 

      46

    • E. 

      48

  • 6. 
    The process of sorting human chromosomes pair by size and morphology is called karyotyping. A modern method employed for kayotyping is called chromosome painting. How were individuals chromosomes shown in a figure in the textbook "painted" as different colors? 
    • A. 

      With a laser

    • B. 

      Using flurorescent antibodies

    • C. 

      Using fluorescent DNA molecules

    • D. 

      Using green fluorescent protein

    • E. 

      By using Photoshop software

  • 7. 
    Chromosomes exist at different levels of condensation, depending on the stage of the cell cycle. 
    • A. 

      True

    • B. 

      False

  • 8. 
    Eucaryotic chromosomes contain many different sites where DNA replication can be initiated.
    • A. 

      True

    • B. 

      False

  • 9. 
    Interphase chromosomes are about _________ times less compact than mitotic chromsomes, but still are about _____ times more compact than a DNA molecule in its extended form. 
    • A. 

      10; 1000

    • B. 

      20:500

    • C. 

      5; 2000

    • D. 

      50: 200

    • E. 

      200: 50

  • 10. 
    A nucleosome contains two molecules each of histones__________ as well as of histones H3 and H4. 
    • A. 

      H1 and H2A

    • B. 

      H2A and H2B

    • C. 

      H1 and H2B

    • D. 

      H1

    • E. 

      H2A

  • 11. 
    Nucleosomes are formed when DNA wraps_____ times aroudn the histone ocatamer in a  _________ coil 
    • A. 

      2.0: right-handed

    • B. 

      2.5 left-handed

    • C. 

      1.7 left-handed

    • D. 

      1.3; right-handed

    • E. 

      5.2; left-handed

  • 12. 
    • A. 

      It is subject to a covalent modifications

    • B. 

      It extends out of the nucleosome core

    • C. 

      It binds to DNA in a sequence-specific manner

    • D. 

      It helps DNA pack tightly

    • E. 

      It contains lysine residues

  • 13. 
    • A. 

      Increase in gene expression

    • B. 

      Gene silencing

    • C. 

      Recruitment of remodeling complexes

    • D. 

      Displacement of histone H1

    • E. 

      Strengthens the nuclear envelope

  • 14. 
    There are five differnt nucleotides that become incorporated into a DNA strand. 
    • A. 

      True

    • B. 

      False

  • 15. 
    DNA replication is considered semiconservative because_______________
    • A. 

      After many rounds of DNA replication, the original DNA double helix is still intact

    • B. 

      Each daughter DNA molecule consists of two new strands copied from the parent DNA molecule

    • C. 

      Each daughter DNA molecule consists of one strand from the parent DNA molecule and one new strand

    • D. 

      New DNA strands must be copied from a DNA template

    • E. 

      None of the above (are) correct

  • 16. 
    How does the total number of replication origins, in bacterial cells compare with thenumber of origins in human cells? 
    • A. 

      1 versus 100

    • B. 

      5 versus 500

    • C. 

      10 versus 1000

    • D. 

      1 versus 10,000

  • 17. 
    Which of the following statements about the newly synthesized strand of human chromosome is true? 
    • A. 

      It was synthesized from a single origion solely by continous DNA synthesis.

    • B. 

      It was synthesized from a single origin by a mixture of continuous and discontinuous DNA synthesis.

    • C. 

      It was synthesized from multiple origins solely by discontinuous DNA synthesis

    • D. 

      It was synthesized from multiple origins by a mixture of continuous and discontinuous DNA synthesis.

    • E. 

      It was synthesized by the use of ATP hydrolysis only.

  • 18. 
    A molecule of bacterial DNA introduced into a yest cell is imported into thenucleus but fails to replicate the yeast DNA. Where do you think the block to replication arises? Choose the protein or protein complex below that is most probably responsible for the failure to replicate bacterial DNA. 
    • A. 

      Primase

    • B. 

      Helicase

    • C. 

      DNA polymerase

    • D. 

      Initiator proteins

    • E. 

      A, B, and C

  • 19. 
    Primase is needed to initiate DNA replication on both the leading strand and the lagging strand. 
    • A. 

      True

    • B. 

      False

  • 20. 
    Primase requires a proofreading function that ensures there are no errors in the RNA primers used for DNA replication. 
    • A. 

      True

    • B. 

      False

  • 21. 
    Because all DNA polymerases synthesize DNA in the 5'-to-3' direction, and the parental strands are antiparallel, DNA replication is accomplished with the use of two mechanisms: continuous and discontinuous replication. Indicate whether the following items relate to continuous replication. 
    • A. 

      Primase

    • B. 

      Single-strand binding protein

    • C. 

      Sliding clamp

    • D. 

      RNA primers

    • E. 

      Leading strand

  • 22. 
    Because all DNA polymerases synthesize DNA in the 5'-to-3' direction, and the parental strands are antiparallel, DNA replication is accomplisehd with the use of two mechanisms: continuous and discontinuous replication. Indicate whether the following items relate to continuous replication.  
    • A. 

      Primase

    • B. 

      Single-strand binding protein

    • C. 

      Sliding clamp

    • D. 

      RNA primers

    • E. 

      Leading strand

  • 23. 
    Because all DNA polymerases synthesize DNA in the 5'-to-3' direction, and the parental strands are antiparallel, DNA replication is accomplished with the use of two mechanisms: continuous and discontinuous replication. Indicate whether the following items relate to discontinuous replication. 
    • A. 

      Primase

    • B. 

      Single-strand binding protein

    • C. 

      Sliding clamp

    • D. 

      RNA primers

    • E. 

      Leading strand

  • 24. 
    Because all DNA polyermases synthesize DNA in the 5'-to-3' direction, and the parental strands are antiparallel, DNA replication is accomplished with the use of two mechanisms: continuous and discontinuous replication. Indicate whether the following items relate to both continuous replication and discontinuous replication. (pick more than 1) 
    • A. 

      Primase

    • B. 

      Single-stranded protein

    • C. 

      Sliding clamp

    • D. 

      RNA primers

    • E. 

      Leading strand

  • 25. 
    The repair of mismatched base pairs or damaged nucleotides in a DNA strand requires a multistep process. Which choice below describes the known sequences of events in this process? 
    • A. 

      DNA damage is recognized, the newly synthesized strand is identified by an existing nick in the backbone, a segment of the new strand is removed by repair proteins, the gap is filled by DNA polymerase, and the strand is sealed by DNA ligase.

    • B. 

      DNA repair polymerase simultaneously removes bases ahead of it and polymerizes the correct sequence behind it as it moves along the template. DNA ligase seals the nicks in the repaired strand.

    • C. 

      DNA damage is recognized, the newly synthesized strand is identified by an existing nick in the backbone, a segment of the new strand is removed by an exonuclease, and the gap is repaired by DNA ligase.

    • D. 

      A nick in the DNA is recognized, DNA repair proteins switch out the wrong base and insert the correct base, and DNA ligase seals the nick.

    • E. 

      RNA polymerase simultaneously removes bases ahead of it and polymerizes the correct sequence behind it as it moves along the template. DNA ligase seals the nicks in the repaired strand.