Biology And Epidemiology Test Quiz!

26 Questions | Total Attempts: 146

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Biology And Epidemiology Test Quiz!

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Questions and Answers
  • 1. 
    The SENSITIVITY of a test is the percentage of all patients with disease present who have a positive test. Which of the following formula represents SENSITIVITY?
    • A. 

      True Negatives / (True Negatives and False Positives)

    • B. 

      (True Positives + True Negatives) / Total number of patients

    • C. 

      True Negatives / (True Negatives and False Negatives)

    • D. 

      True Positives / (True Positives + False Negatives)

    • E. 

      True Positives / (True Positives and False Positives)

  • 2. 
    The SPECIFICITY of a test is the percentage of all patients without disease who have a negative test. Which of the following formula represents SPECIFICITY?
    • A. 

      True Negatives / (True Negatives and False Positives)

    • B. 

      (True Positives + True Negatives) / Total number of patients

    • C. 

      True Negatives / (True Negatives and False Negatives)

    • D. 

      True Positives / (True Positives + False Negatives)

    • E. 

      True Positives / (True Positives and False Positives)

  • 3. 
    The EFFICIENCY of a test is the percentage of the times that the test give the correct answer compared to the total number of tests. Which of the following formula represents TEST EFFICIENCY?
    • A. 

      True Negatives / (True Negatives and False Positives)

    • B. 

      (True Positives + True Negatives) / Total number of patients

    • C. 

      True Negatives / (True Negatives and False Negatives)

    • D. 

      True Positives / (True Positives + False Negatives)

    • E. 

      True Positives / (True Positives and False Positives)

  • 4. 
    The PREDICTIVE VALUE of a test is a measure of the times that the value (positive or negative) is the true value. Which of the following formula represents POSITIVE PREDICTIVE VALUE ?
    • A. 

      True Negatives / (True Negatives and False Positives)

    • B. 

      (True Positives + True Negatives) / Total number of patients

    • C. 

      True Negatives / (True Negatives and False Negatives)

    • D. 

      True Positives / (True Positives + False Negatives)

    • E. 

      True Positives / (True Positives and False Positives)

  • 5. 
    The PREDICTIVE VALUE of a test is a measure of the times that the value (positive or negative) is the true value. Which of the following formula represents NEGATIVE PREDICTIVE VALUE ?
    • A. 

      True Negatives / (True Negatives and False Positives)

    • B. 

      (True Positives + True Negatives) / Total number of patients

    • C. 

      True Negatives / (True Negatives and False Negatives)

    • D. 

      True Positives / (True Positives + False Negatives)

    • E. 

      True Positives / (True Positives and False Positives)

  • 6. 
    What are abnormal accumulations of triglycerides within parenchymal cells called?
    • A. 

      Brown Atrophy

    • B. 

      Steatosis

    • C. 

      Fatty Change

    • D. 

      Niemann-Pick disease

  • 7. 
    What is an accumulation of cholesterol within the intimal layer of the aorta and large arteries called?
    • A. 

      Xanthomas

    • B. 

      Brown Atrpohy

    • C. 

      Steatosis

    • D. 

      Atherosclerosis

  • 8. 
    What is an accumulation of cholesterol within the subepithelial connective tissue called?
    • A. 

      Xanthoma

    • B. 

      Brown Atrpohy

    • C. 

      Steatosis

    • D. 

      Atherosclerosis

  • 9. 
    Local deposition of calcium in dying tissues in the absence of calcium metabolism derangements is called _ _ _ _ _ _ _ _ _ calcification.
  • 10. 
    Metastatic calcification is the deposition of calcium due to hypercalcemia secondary to some disturbance in calcium metabolism.
    • A. 

      True

    • B. 

      False

  • 11. 
    Which of the following is true about Phospholipases?
    • A. 

      Inhibited by steroids

    • B. 

      Drives the cell cycle by phosphorylating protein critical for cell cycle transitions.

    • C. 

      Activated by increased intracellular calcium

    • D. 

      Breaks down phospholidpids

    • E. 

      Antioxidant

    • F. 

      Most abundant glycoprotein in the basement membrane

  • 12. 
    The most abundant glycoprotein in the basement membrane is _ _ _ _ _ _ _.
  • 13. 
    Which of the following can induce apoptosis and promote cell survival?
    • A. 

      IFN-γ

    • B. 

      IL-1

    • C. 

      Leukotrienes

    • D. 

      Lipoxins

    • E. 

      Prostacyclin

    • F. 

      TNF

  • 14. 
    Which of the following is the major macrophage activating cytokine?
    • A. 

      IFN-γ

    • B. 

      IL-1

    • C. 

      Leukotrienes

    • D. 

      Lipoxins

    • E. 

      Prostacyclin

    • F. 

      TNF

  • 15. 
    Which of the following is created by the lipoxygenase pathway, is an intense vasoconstrictor, and causes bronchospasm and increased vascular permeability?
    • A. 

      IFN-γ

    • B. 

      IL-1

    • C. 

      Leukotrienes

    • D. 

      Lipoxins

    • E. 

      Prostacyclin

    • F. 

      TNF

  • 16. 
    Which of the following inhibits leukocyte recruitment?
    • A. 

      IFN-γ

    • B. 

      IL-1

    • C. 

      Leukotrienes

    • D. 

      Lipoxins

    • E. 

      Prostacyclin

    • F. 

      TNF

  • 17. 
    Which of the following inhibits platelet aggregation?
    • A. 

      IFN-γ

    • B. 

      IL-1

    • C. 

      Leukotrienes

    • D. 

      Lipoxins

    • E. 

      Prostacyclin

    • F. 

      TNF

  • 18. 
    Non-inflammatory edema is usually exudate due to hydrodynamic arrangements.
    • A. 

      True

    • B. 

      False

  • 19. 
     1. ________ is an active process resulting from arteriolar dilation → _________.  2. ________ is a passive process resulting from decreased venous outflow → .  
    • A. 

      1. Hyperaemia → cyanosis, 2. Congestion → erythema

    • B. 

      1. Hyperaemia, → erythema, 2. Congestion → cyanosis

    • C. 

      1. Congestion, → cyanosis, 2. Hyperaemia → erythema

    • D. 

      1. Congestion, → erythema, 2. Hyperaemia → cyanosis

  • 20. 
    _ _ _ _ _ _ _ _ _ _ _ _ inhibits thrombin and other serine proteases.
  • 21. 
    Proteins C and S are Vitamin K dependent proteins:
    • A. 

      Activate factors IX and X

    • B. 

      Inactivate factors IX and X

    • C. 

      Activate factors II and III

    • D. 

      Inactivate factors II and III

    • E. 

      Activate factors V and VIII

    • F. 

      Inactivate factors V and VIII

  • 22. 
    Which of the following are risk factors for bladder cancer?
    • A. 

      Cyclophosphamide

    • B. 

      Tobacco smoke

    • C. 

      E coli

    • D. 

      Schistosomiasis

    • E. 

      Aromatic amines, particularly benzidine and a-and ß-naphthylamine

    • F. 

      Family History

  • 23. 
    The maintenance of long-term immunity of some vaccines (including toxoids, recombinant subunit and polysaccharide conjugate vaccines), requires multidose immunization courses consisting of 2 – 3 inoculations, followed by periodic administration of booster doses. Doses administered at intervals less than the minimum interval can lead to a suboptimal immune response. In clinical practice, however, it is recommended that vaccine doses administered ≤  __  days before the minimum interval may be counted as valid (except rabies vaccine).
    • A. 

      1

    • B. 

      2

    • C. 

      4

    • D. 

      7

  • 24. 
    An autosomal recessive disorder resulting from mutations in the gene encoding glucocerebrosidase.
    • A. 

      Amyloidosis

    • B. 

      Chediak-Higashi Syndrome

    • C. 

      Gaucher Disese

    • D. 

      Nieman-Pick Disease

    • E. 

      Sarcoidosis

    • F. 

      Wagener's Granulomatosis

  • 25. 
    Cyclin-dependent kinases drive the cell cycle by __________ critical target proteins that are required for the progression of cells to the next stage of the cell cycle.
    • A. 

      Carboxylating

    • B. 

      Hydroxylating

    • C. 

      Oxidating

    • D. 

      Phophorylating