Bio1334 Genetics - Molecular Genetics - DNA Replication (Lecture Four)

20 Questions | Total Attempts: 262

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Bio1334 Genetics - Molecular Genetics - DNA Replication (Lecture Four)

• Demonstrate a general understanding of the eukaryotic cell cycle • Demonstrate a sound understanding of the principles of DNA replication


Questions and Answers
  • 1. 
    ____________ are highly repetitive DNA that allow the ends of chromosomes to be replicated; also protect the ends of chromosomes as being mistaken as broken 
  • 2. 
    _________ are repetitive DNA that forms the spindle attachment in mitosis.
  • 3. 
    ________________ are special sequences where duplication of the DNA begins; each chromosome will have many. 
  • 4. 
    ______________ replication means that each new DNA molecule produced in replication contains one of the original strands of DNA and one new strand.
  • 5. 
    Name the enzyme responsible for DNA synthesis.
  • 6. 
    True or False:DNA synthesis occurs in a 5' to 3' direction.
    • A. 

      True

    • B. 

      False

  • 7. 
    • A. 

      True

    • B. 

      False

  • 8. 
    Name the enzyme involved in 'proofreading' DNA by removing nucleotides from the 3' end of a polynucleotide chain.
  • 9. 
    DNA replication is bidirectional, resulting in the formation of ___________________.
  • 10. 
    True or False:Bacterial DNA contains histone proteins.
    • A. 

      True

    • B. 

      False

  • 11. 
    Name the short, newly synthesised DNA fragments found on the lagging template during DNA synthesis
  • 12. 
    Name the enzyme that prevents base pairing until DNA polymerase arrives.
  • 13. 
    What is the name given to proteins that load histones onto newly synthesised DNA?
  • 14. 
    Helicase unwinding of DNA causes supercoiling (“twists”) ahead of the replication fork which need to be unwound by enzymes called _____________. 
  • 15. 
    _______________ proteins detect and correct incorrect base pairing in newly-synthesised DNA.