B63: Amino Acid Metabolism I, Nitrogen Metabolism

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Amino Acid Quizzes & Trivia

SGU Biochemistry, Fall 2009 - Lecture 63: Amino Acid Metabolism I and Nitrogen MetabolismQuestions from lecture notes of Dr. Upadhya


Questions and Answers
  • 1. 
    ____ proteins are the major source of amino acids for the amino acid pool (Lecture 63, p. 1).
  • 2. 
    There is increased tissue protein synthesis in _____ nitrogen balance (Lecture 63, p. 3).
  • 3. 
    The rate of tissue protein ____ is equal to the rate of protein catabolism. (Lecture 63, p. 1)
  • 4. 
    ____ ____ are used for the synthesis of nitrogenous compounds like heme, creatine, purines, pyrimidines, neurotransmitters/hormones (Lecture 63, p. 1).
  • 5. 
    Amino acids undergo catabolism to form _____ that is detoxified to urea in the liver (Lecture 63, p. 1).
  • 6. 
    In a healthy adult, tissue protein levels remain ____, approximately 12 kg (Lecture 63, p. 2).
  • 7. 
    ____ proteins are constantly being catabolized - approximately 400 g/day (Lecture 63, p. 1).
  • 8. 
    Damaged or unneeded endogenous, intracellular proteins are degraded by the ____ (Lecture 63, p. 2).
    • A. 

      Ubiquitin-proteasome pathway

    • B. 

      Lysosomal pathwa

  • 9. 
    In a healthy, well-fed adult, the input of amino acids is equal to the output of amino acids.  The amino acid pool is in a ___ ____ (Lecture 63, p. 2).
  • 10. 
    The ____ pathway is ATP dependant (Lecture 63, p. 2).
    • A. 

      Ubiquitin-proteasome

    • B. 

      Lysosomal

  • 11. 
    When the input of dietary nitrogen equals the output of nitrogen in urine, then an adult is said to be in a state of nitrogen ____ (Lecture 63, p. 3).
  • 12. 
    ____ is observed when the diet is deficient in protein or any of the essential amino acids (Lecture 63, p. 3).
    • A. 

      Positive nitrogen balance

    • B. 

      Negative nitrogen balance

  • 13. 
    The ____ degrades extracellular proteins, like plasma proteins and proteins taken up by endocytosis (Lecture 63, p. 2).
    • A. 

      Ubiquitin-proteasome pathway

    • B. 

      Lysosomal pathway

  • 14. 
    When intake of dietary nitrogen is greater than the output of nitrogen, the state is known as ____ ____ ____ (Lecture 63, p. 3).
  • 15. 
    When the intake of nitrogen is less than the output of nitrogen, the state is known as ____ ____ ____ (Lecture 63, p. 3).
  • 16. 
    • A. 

      Positive nitrogen balance

    • B. 

      Negative nitrogen balance

  • 17. 
    The ____ is non-energy dependent (Lecture 63, p. 2).
    • A. 

      Ubiquitin-proteasome pathway

    • B. 

      Lysosomal

  • 18. 
    Growth periods during childhood and adolescence as well as pregnancy exhibit ____ (Lecture 63, p. 3).
    • A. 

      Positive nitrogen balanace

    • B. 

      Negative nitrogen balance

  • 19. 
    Which of the following statements is true? (Lecture 63, p. 3).
    • A. 

      All amino acids are glucogenic

    • B. 

      Amino acid catabolism is increased during starvation

    • C. 

      All amino acids are essential amino acids

    • D. 

      The major excretory end product of amino acid catabolism is ammonia

    • E. 

      Tissue protein synthesis is decreased during periods of growth

  • 20. 
    There is a higher amount of tissue protein catabolism in states of ____ (Lecture 63, p. 3).
    • A. 

      Positive nitrogen balance

    • B. 

      Negative nitrogen balance

  • 21. 
    ____ is seen in starvation, chronic illness (infections), cancer, and uncontrolled diabetes mellitus (Lecture 63, p. 3).
    • A. 

      Positive nitrogen balance

    • B. 

      Negative nitrogen balance

  • 22. 
    Ammonia is detoxified to urea via the __ cycle in the liver (Lecture 63, p. 4).
  • 23. 
    Along with the inflammatory mediators, ____ is the major hormonal mediator (Lecture 63, p. 4).
  • 24. 
    There is increased muscle proteolysis and loss of tissue protein in states of _____ (Lecture 63, p. 3).
    • A. 

      Positive nitrogen balance

    • B. 

      Negative nitrogen balance

  • 25. 
    Liver is the site where most of the amino acids release their amino groups as ____ (Lecture 63, p. 4).
  • 26. 
    The carbon skeletons of the amino acids are used for _____ (Lecture 63, p. 4).
  • 27. 
    In infection, the liver synthesizes a group of proteins known as the ___ phase proteins (Lecture 63, p. 4).
  • 28. 
    ___ is the major end-product of nitrogen metabolism (Lecture 63, p. 4).
  • 29. 
    Hartnup's disease is characterized by an inherited defect in the transport of the neutral amino acids like tryptophan, decreasing dietary absorption of tryptophan and increasing ____ of tryptophan (Lecture 63, p. 6).
  • 30. 
    _____ is characterized by decreased tubular reabsorption of cystine, along with diabasic amino acids lysine, ornithine, arginine) due to an inherited deficiency of the cystine transporter (Lecture 63, p. 5).