Anatomy Long Quiz 6 explores the development of the urinary and genital systems, focusing on key stages and genetic influences. It assesses understanding of structures like the urogenital ridge, paramesonephric ducts, and primitive sex cords, crucial for students in medical and biological sciences.
XY chromosomes express SRY which expresses SOX9 which will then trigger WNT4 gene in males
SOX9 inhibits the expression of WNT4
WNT4 leads to expression of DAX1 and other genes. DAX1 inhibits SOX9
The development of testis allows for the inhibition of Mullerian Inhibiting Substance
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Uterine tube, uterus, upper portion of vagina
Efferent ductules, epididymis, vas deferens
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Inital
Developing
Indifferent
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In males, under the influence of testis determining factor, primitive sex cords continue to proliferate and penetrate deep into the medulla to form testis chords
In females, the absense of testis determining factor causes dissociation of primitive sex cords into irregular cell clusters around primitive germ cells in the future medulla forming medullary cords that will eventually be replaced by vascular stroma of ovarian medulla
Tunica albuginea is a layer of elastic tissue that separates testis cords from surface epithelium
Interstitial cells of leydig form from sporadic mesenchyme cell groups in between testis cords. They produce testosterone allowing for differentiation of genital ducts and external genilia.
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True
False
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False
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Mesonephric (Woliffian) ducts develop separately from the urinary system and develop only under the influence of testosterone
Paramesonephric (Mullerian) ducts are longitudinal invagination of epithelium on anterolateral surgace of urogenital ridge.
The paramesonephric ducts degenerate in females under the influence of MIS released by Sertoli cells
The Mullerian ducts develop to the duct system in females
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True
False
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They fuse caudally to form the endometrial lining of the uterus
Cranially, the ducts remain separate to form uterine tubes
They migrate and fuse medially after grabbing a transverse fold of mesoderm (future peritoneum) forming the broad ligament of the uterus
They fuse anteriorly to form the myometrium and perimetrium of the uterus
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True
False
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Failure of paramesonephric ducts to fuse resulting in formation of 2 horns of uterus in a common vagina
Failure of fusion of parameonephric ducts and sinovaginal bulbs
Failure of sinovaginal bulb to develop or a vaginal plate to canalize
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Failure of parameonephric ducts to fuse resulting in formation of 2 horns of uterus in a common vagina
Failure of fusion of paramesonephric ducts and sinovaginal bulbs
Failure of sinovaginal bulb to develop or vaginal plate to canalize
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Failure of paramesonephric ducts to fuse resulting in formation of 2 horns of uterus in a common vagina.
Failure of fusion of paramesonephric ducts and sinovaginal bulbs
Failure of sinovaginal bulb to develop or vaginal plate to canalize
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Cranial part develops from the most cranial part of fused paramesonephric tubules that canalize forming vaginal fornices & upper 1/3 of vagina
Caudal part develops from sino-vaginal bulbs
The sino vaginal bulbs fuse to form a solid vaginal plate that canalizes forming lower 2/3 of vagina
The most distal part of the vaginal tube is enclosed by a single layer membrane (hymen) that has small holes for passage of vaginal secretions and menstruation
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False
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Persistence of connection between processus vaginalis cavity & scrotal sac
Partial persistence of a cystic cavity during obliteration of processus vaginalis
↓ ↓ testosterone causes failure of one or both testicles to descend in the scrotum with failure to produce mature sperms
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Causes the slow growth of urethral folds
Slows down the growth of genital tubercle
Causes rapid elongation of genital tubercle (phallus)
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Estrogen release slows down the growth of genital tubercle resulting in the formation of clitoris (solid structure)
Urethral folds also undergo very slow growth & stay separated from each other resulting in formation of labia minora surrounding vestibule (urogenital groove)
Urethra is derived from only one part (membranous urethra only ). It is short & wide.
Genital swellings undergo rapid growth and stay separated and in place from the labia majora
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Growing phallus pulls urethral folds forward with it leading to formation of lateral walls of the urethral groove
The urethra is derived from only one part
Epithelial cells over glans penis proliferate & invade inward to form solid external urethral meatus that canalizes & becomes continuous with penile urethra
Prostatic & membranous parts of the urethra arise from the pelvic part of urogenital sinus
Penile part of urethra arises from epithelial proliferation
Glandular parts: arises from urethral folds
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Incomplete fusion of urethral folds leading to abnormal opening(s) along the inferior aspect of shaft of the penis
Too far caudal genital tubercle causes opening on the dorsum of the penis with exposure of the urethra
Failure of paramesonephric ducts to fuse resulting in formation of 2 horns of uterus in a common vagina.
Failure of sinovaginal bulb to develop or vaginal plate to canalize
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Incomplete fusion of urethral folds leading to abnormal opening(s) along the inferior aspect of shaft of the penis
Too far caudal genital tubercle causes opening on the dorsum of the penis with exposure of the urethra
Failure of sinovaginal bulb to develop or vaginal plate to canalize
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It is a type of true hermaphroditism
Progesterone can no longer be converted to deoxycorticosterone and as such gets converted to DHEA and thus testosterone.
There is ovarian development but male external genitalia
These patients have low cortisol but ACTH
As a result of decreased aldosterone these patients present with hypotension, hyponatremia, and hyperkalemia, as well as increased plasma renin
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Androgen insensitivity syndrome
Klinefelter's syndrome
Turner's syndrome
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Intravenous Pyelogram
Contrast media is administered to the patient intravenously, allowing visulaization of renal pelvis, ureters, and bladder
Is replacing CT with contrast because it's more sensitive
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True
False
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40-50% are visible on plain film
Caused by infection, urinary stasis, several systemic diseases
Uteric calculi are very painful, but pass within 3-4 days
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Are calcified venous thrombi
Have a lucent center
Are usually found in the abdomen
Are of little clinical significance
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Are also called leiomyoma, myoma, or fibromyoma
Are a common benign tumor of the female reproductive tract, occuring in 40% of women over 40
They are usually asymptomatic but may present with heavy menstration, pelvic pressure, frequent urinaton or constipation
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Renal Corpuscle
Bowman's capsule
Urinferous tubule
Ureter
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Collecing tubules
Renal corpuscle
Proximal convoluted tubule
Uriniferous tubule
Henle's loop
Distal convoluted tubule
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Loops of henle
Lower part of collecting tubules
Bellini ducts
Renal corpuscles
Proximal and distal convoluted tubules
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Are part of the cortex
Are found in the medulla
Are also called collecting tubules
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