Urinary Incontinence Questions

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  • 1/64 Questions

    Which of the following may improve urinary incontinence?

    • Correcting comorbid disease states
    • Correcting functional impairments
    • Optimizing medication therapy
    • All of the above
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About This Quiz

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Urinary Incontinence Questions - Quiz

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  • 2. 

    Stress UI is leakage that occurs with ­­­________ in intra-abdominal pressure and is associated with ­­­________ urethral sphincter support.

    • An increase; impaired

    • A decrease; impaired

    • An increase; improved

    • A decrease; improved

    Correct Answer
    A. An increase; impaired
  • 3. 

    Which agent is currently available as a generic medication?

    • Oxybutynin

    • Solifenacin

    • Darifenacin

    • Fesoterodine

    Correct Answer
    A. Oxybutynin
  • 4. 

    The possible causes in urethral closure (resting) pressure decreases with age in women are:

    • Alterations in the mucosal and sub-mucosal layers

    • Decreased vascular density and blood flow

    • Both A and B

    • None of the above

    Correct Answer
    A. Both A and B
  • 5. 

    Which pharmalogical intervention below do you think would be the BEST treatment of urinary incontinence?

    • Estrogen

    • Duloxetine

    • Amitriptyline

    • Oxybutynin

    Correct Answer
    A. Oxybutynin
  • 6. 

    Urethral closure pressure decreases with ____________.

    • Gender

    • Age

    • Physical activity

    • Caffeine

    Correct Answer
    A. Age
  • 7. 

    What type of leakage is characterized by an increase in intra-abdominal pressure and is associated with impaired urethral sphincter support?

    • Urge UI

    • Stress UI

    • Explosive UI

    • Bladder UI

    Correct Answer
    A. Stress UI
  • 8. 

    Urethral closure (resting) pressure decreases with age possible cause(s) in women include:

    • Alterations in the mucosal and sub-mucosal layers

    • Increased vascular density

    • Decreased blood flow

    • A and C only

    Correct Answer
    A. A and C only
  • 9. 

    Which formulation of oxybutynin has the lowest published rate of dry mouth and constipation?

    • Oral syrup

    • Gelnique 400mg/gm

    • Oral tablet

    • Transdermal jelly 100mg/gm

    Correct Answer
    A. Transdermal jelly 100mg/gm
  • 10. 

    ________ is better with ________ formulations especially in patients who are already taking multiple daily medications.

    • Compliance; once daily

    • Tolerance; twice daily

    • Efficacy; once daily

    • Efficacy; three times daily

    Correct Answer
    A. Compliance; once daily
  • 11. 

    The major age-related change(s) in the bladder for men and women include:

    • Detrusor overactivity (DO)

    • Diminished detrusor contractile strength

    • Obstruction due to the prostate

    • A and B

    Correct Answer
    A. A and B
  • 12. 

    Which medication is available in a topical patch formulation?

    • Vesicare

    • Enablex

    • Oxybutynin

    • Sanctura

    Correct Answer
    A. Oxybutynin
  • 13. 

    Which of the following adverse effects of anti-muscarinics is incorrect:

    • Dry mouth

    • Constipation

    • Alopecia

    • Altered cognition

    Correct Answer
    A. Alopecia
  • 14. 

    Older persons tend to have smaller bladder capacity, lower urine flow rate, and which of the following?

    • Decreased post-voiding residual volume

    • Increased post-voiding residual volume

    • Decreased nocturia

    • Increased detrusor contractile strength

    Correct Answer
    A. Increased post-voiding residual volume
  • 15. 

    The possible causes in urethral closure (resting) pressure decreases with age in women are:

    • Alterations in the mucosal and sub-mucosal layers

    • Decreased vascular density and blood flow

    • Both A and B

    • None of the above

    Correct Answer
    A. Both A and B
  • 16. 

    The major age-related changes in the bladder included increased involuntary contractions of what?

    • Detrusor overactivity (DO)

    • Detrusor underactivity (DU)

    • Pyloric sphincter overactivity (PO)

    • None of the above

    Correct Answer
    A. Detrusor overactivity (DO)
  • 17. 

    One study has shown that _______ decreases the frequency of UI when administered in addition to behavioral treatment in nursing-home residents, as measured by “wet checks”?

    • Tolerodine

    • Oxybutynin

    • Darlfenacin

    • Solifenacin

    Correct Answer
    A. Oxybutynin
  • 18. 

    In women, mechanical urethral obstruction is usually due to:

    • Pelvic organ prolapse

    • Prior surgery

    • Prostate disease

    • A and B only

    Correct Answer
    A. A and B only
  • 19. 

    Which of the following UI therapies had the lowest tolerance for dry mouth?

    • Tolterodine

    • Oxybutynin

    • Darifenacin

    • Solifenacin

    Correct Answer
    A. Oxybutynin
  • 20. 

    The major age-related changes in the bladder included increased involuntary contractions of what?

    • Detrusor overactivity (DO)

    • Detrusor underactivity (DU)

    • Pyloric sphincter overactivity (PO)

    • None of the above

    Correct Answer
    A. Detrusor overactivity (DO)
  • 21. 

    In persons age >50, tolterodine IR 2mg BID has been shown to produce similar effects to ___________ with respect to reduction in urge UI and frequency, but was tolerated significantly better with respect to ADE's (dry mouth and need for dose reduction).

    • Solifenacin

    • Darifenacin

    • Oxybutinin

    • None of the above

    Correct Answer
    A. Oxybutinin
  • 22. 

    Based on efficacy, which of the following is an appropriate antimuscarinic drug for the treatment of UI in an elderly patient?

    • Ditropan

    • Detrol

    • Diprivan

    • A and B

    Correct Answer
    A. A and B
  • 23. 

    Which of the following antimuscarinic drugs has shown higher efficacy rates in reducing urge UI and resulting in cure

    • Oxybutynin

    • Tolterodine

    • Darifenacin

    • All of the above have similar efficacies in reducing urge UI and resulting in cure

    Correct Answer
    A. All of the above have similar efficacies in reducing urge UI and resulting in cure
  • 24. 

    Which of the following is the most concerning antimuscarinic drug-related ADE for older adults in the treatment of urinary incontinence?

    • Constipation

    • Cognitive impairment

    • Diarrhea

    • UTI

    Correct Answer
    A. Cognitive impairment
  • 25. 

    Which of the following statements is false?

    • Major age-related changes in the bladder include increased involuntary contractions

    • Urinary incontinence can be attributed to detrusor overactivity alone

    • Diminished detrusor contractile strength is a major age-related change

    • Urethral closure pressure decreases with age

    Correct Answer
    A. Urinary incontinence can be attributed to detrusor overactivity alone
  • 26. 

    Older populations tend to have all of the following characteristics that lead to urinary incontinence EXCEPT:

    • Smaller voided volumes

    • Higher urine flow rate

    • Smaller bladder capacity

    • Increased post-voiding residual volume

    Correct Answer
    A. Higher urine flow rate
  • 27. 

    Which of the following antimuscarinic agents is NOT metabolized by CYP450?

    • Trospium

    • Darifenacin

    • Oxybutinin

    • Solifenacin

    Correct Answer
    A. Trospium
  • 28. 

    Stress UI is a leakage that is associated with all of the following features EXCEPT:

    • Increased intra-abdominal pressure

    • Sphincter damage impairing closure

    • Detrusor overactivity

    • Impaired uretheral support

    Correct Answer
    A. Detrusor overactivity
  • 29. 

    Which one of the following statements are FALSE about antimuscarinic:

    • All antimuscarinics are metabolized by CYP-450 enzymes

    • During antimuscarinic therapy with older adults a major drug related ADE of concern is cognitive impairment

    • Currently there is insufficient evidence that one agent with in this class is "safer" for all older patients

    • Agents within this class prescribed for UI may be associated with drug-disease interactions ie advance diabetes, and parkison's disease

    Correct Answer
    A. All antimuscarinics are metabolized by CYP-450 enzymes
  • 30. 

    Desmopressin acetate should not be used for nocturia in older persons because of the risk of:

    • Hypokalemia

    • Hypocalcemia

    • Hyponatremia

    • Hypoalbuminemia

    Correct Answer
    A. Hyponatremia
  • 31. 

    Which is not a predominate factor in drug selection?

    • Differences in the incidence of ADEs

    • Formulation and manufacturer of the drug

    • Avoidance of ADEs to which the patient may be susceptible

    • Additional patient-based issues that may complicate the use of the drug

    Correct Answer
    A. Formulation and manufacturer of the drug
  • 32. 

    The major age related changes in the bladder include the following EXCEPT?

    • Detrusor overactivity

    • Diminished detrusor contractile strength

    • Increased number and density of striated and smooth muscle

    • Small bladder capacity

    Correct Answer
    A. Increased number and density of striated and smooth muscle
  • 33. 

    Urge UI is thought to be caused by:

    • Detrusor overactivity

    • Impaired compensatory mechanisms

    • Bladder outlet obstruction

    • A and B only

    Correct Answer
    A. A and B only
  • 34. 

    Current pharmacological agents for urinary incontinence target:

    • Alpha adrenergic receptors

    • Beta adrenergic agonists

    • Serotonergic receptors

    • Muscarinic receptors

    Correct Answer
    A. Muscarinic receptors
  • 35. 

    ________ oxybutin is associated with __________ published rates of dry mouth and constipation but the incidence of skin reaction to patch is ~15%.

    • Topical; lowest

    • IV; lowest

    • Topical; highest

    • IV; highest

    Correct Answer
    A. Topical; lowest
  • 36. 

    Which of the following showed decrease urgency with UI when administered in addition to behavioral treatment?

    • Solefenacin

    • Darifenacin

    • Detrol LA

    • Oxybutynin IR

    Correct Answer
    A. Oxybutynin IR
  • 37. 

    The major age-related changes in urethral pathophysiology

    • Increased urethral closing pressure

    • The number but NOT density of striated fibers decreases

    • Prostate-induced mechanical urethral obstruction is common in females

    • None of the above

    Correct Answer
    A. None of the above
  • 38. 

    What cellular mechanisms are likely responsible for age-related changes in the bladder?

    • “dense bands” in smooth muscle

    • Decreased axon sensitivity

    • Narrowing of spaces between muscle cells

    • Acetylcholine accumulation

    Correct Answer
    A. “dense bands” in smooth muscle
  • 39. 

    The correct brand name match for the following generics (tolterodine, solifenacin, darifenacin and fesoterodine) in order are:

    • Detrol, Vesicare, Enablex, Toviaz

    • Sanctura, Vesicare, Toviaz, Enablex

    • Detrol, Enablex, Toviaz, Vesicare

    • Sanctura, Oxytrol, Enablex, Evista

    Correct Answer
    A. Detrol, Vesicare, Enablex, Toviaz
  • 40. 

    Tricyclic antidepressants for urinary incontinence are limited by which adverse effect?

    • Diarrhea

    • Anticholinergic effects

    • Nausea and vomiting

    • Constipation

    Correct Answer
    A. Anticholinergic effects
  • 41. 

    Which dose of salifenacin was assoicated with urinary retention and discontinuation ?

    • 5 mg

    • 10 mg

    • 4 mg

    • 15 mg

    Correct Answer
    A. 10 mg
  • 42. 

    Which of the following is not associated with UI in elderly patients?

    • Elderly patients are at risk for developing adverse effects of UI medications

    • Etiology is usually a specific condition of the lower urinary tract

    • Concurrent medications should be considered for the cause of UI

    • UI is associated with an increase in fall risk

    Correct Answer
    A. Etiology is usually a specific condition of the lower urinary tract
  • 43. 

    Which of these is NOT a major age related related change in the bladder?

    • Increased involuntary contractions

    • Detrusor overactivity

    • Decreased involuntary contractions

    • Diminished detrusor contractile strength

    Correct Answer
    A. Decreased involuntary contractions
  • 44. 

    Urethral age-related changes in men/women can be attributed to?

    • Decrease in density of striated and smooth muscle

    • Prior surgery

    • Increased involuntary contractions due to detrusor overactivity

    • Pelvic organ prolapse

    Correct Answer
    A. Increased involuntary contractions due to detrusor overactivity
  • 45. 

    Which agent is associated with the lowest rates of dry mouth and constipation?

    • Tolterodine

    • Darifenacin

    • Oxybutynin

    • Fesoterodine

    Correct Answer
    A. Oxybutynin
  • 46. 

    Which of the following agents with an indication for stress UI does NOT have robust evidence?

    • Duloxetine

    • Oxybutynin

    • Tolterodine

    • Darifenacin

    Correct Answer
    A. Duloxetine
  • 47. 

    What is a possible cause of decreased urethral closure pressure? 

    • Increased vascular density and blood flow

    • Diminished detrusor contractile strength

    • Alterations in the mucosal and submucosal layers

    • "ultra-close abutments" in smooth muscle cells to facilitate

    Correct Answer
    A. Alterations in the mucosal and submucosal layers
  • 48. 

    Which of the following medication class is not associated with causing or worsening incontinence?

    • NSAIDS

    • Estrogens

    • Statins

    • TCAs

    Correct Answer
    A. Statins
  • 49. 

    Which if the following was associated with more urinary retention and an increase incidence of discontinuation due to ADE’s?

    • Detrol LA 2mg

    • Solifenacin 10 mg

    • Oxybutynin 5mg

    • Solifenacin 5 mg

    Correct Answer
    A. Solifenacin 10 mg

Quiz Review Timeline (Updated): Aug 26, 2020 +

Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.

  • Current Version
  • Aug 26, 2020
    Quiz Edited by
    ProProfs Editorial Team
  • May 09, 2012
    Quiz Created by
    SCopp
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