Pre-reg Sample Open Book Exam

20 Questions | Total Attempts: 355

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Pre-reg sample open book paper 2010


Questions and Answers
  • 1. 
    What is the usual dose of bendroflumethiazide in hypertension
    • A. 

      1.25mg

    • B. 

      2.5mg

    • C. 

      5mg

    • D. 

      10mg

    • E. 

      25mg

  • 2. 
    Which of these situations would not necessarily require immediate withdrawal of the drug?
    • A. 

      A 59 year old man taking amiodarone who develops hypothyroidism

    • B. 

      A 72 year old woman who gets a headache after recently being initiated on dipyridamole

    • C. 

      A 23 year old woman taking phenytoin who develops a widespread rash

    • D. 

      A 55 year old man with a recent pulmonary embolism who has a nose bleed while taking warfarin

    • E. 

      A 77 year old woman who develops hypokalaemia whilst taking bumetanide

  • 3. 
    Which of these would be the most suitable antibiotic to give to a patient who has a history of anaphylaxis with penicillins
    • A. 

      Meropenem

    • B. 

      Tazocin

    • C. 

      Cefuroxime

    • D. 

      Gentamycin

    • E. 

      Co-amoxiclav

  • 4. 
    Which of the following drugs is not an enzyme inducer?
    • A. 

      Phenytoin

    • B. 

      Carbemazepine

    • C. 

      Rifampicin

    • D. 

      Griseofulvin

    • E. 

      Fluconazole

  • 5. 
    Which of the following vitamins increases absorption of iron from plant sources?
    • A. 

      A

    • B. 

      B12

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 6. 
    A 48-year-old woman asks you to recommend a treatment for itching. The itchiness is widespread over her body and started about 2 days ago. She has a yellow-brown tanned appearance, and has returned from a holiday in Turkey 2 weeks ago. On questioning she reveals that she feels generally unwell and has difficulty sleeping. She does NOT take any medication and since returning from holiday she has not changed her diet, or used any new cosmetics or detergents. Which one of the following courses of action is the most appropriate for you to take?
    • A. 

      Advise her to take chlorphenamine tablets

    • B. 

      Advise her to use calamine lotion

    • C. 

      Advise her to apply hydrocortisone cream 1% twice a day to the affected areas (except her face)

    • D. 

      Advise her to use a soap substitute such as emulsifying ointment

    • E. 

      Advise her to see her GP

  • 7. 
    For which of these indications can OTC hdrocortisone cream be sold?
    • A. 

      Nappy rash for 18 month old todder

    • B. 

      Shaving rash on a 33 year old man

    • C. 

      53 year old women with a nickel allergy rash on her wrist

    • D. 

      Vulval allergy and rask on a 42 year old woman

    • E. 

      Insect bite on a 9 year old boy

  • 8. 
    Which of these drugs have a narrow therapeutic range?
    • A. 

      Gentamycin

    • B. 

      Methotrexate

    • C. 

      Lithium

    • D. 

      Phenobarbital

    • E. 

      Itraconazole

  • 9. 
    Which of the following drugs is least likely to cause blood disorders?
    • A. 

      Carbimazole

    • B. 

      Amiodarone

    • C. 

      Phenytoin

    • D. 

      Mesalazine

    • E. 

      Methotrexate

  • 10. 
    Which one of the following side effects of hydrocortisone is caused by its mineralocorticoid activity?
    • A. 

      Osteoporosis

    • B. 

      Diabetes

    • C. 

      Muscle wasting

    • D. 

      Hypertension

    • E. 

      Skin thinning

  • 11. 
    Directions:  For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:   A if 1,2 and 3 are correct B if 1 and 2 only are correct C if 2 and 3 only are correct D if 1 only is correct E if 3 only is correct   Directions Summarised A 1,2,3 B 1,2 C 2,3 D 1 only E 3 only   The Responsible Pharmacist Regulations 2008, which come into force on 1 October this year, will replace the following provisions in the Medicines Act 1968.   1.      Personal control 2.      Supervision 3.      Superintendent pharmacist
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 12. 
    The supply of which one of the following would be unlawful? Select the best answer.
    • A. 

      A prescription for six weeks supply of a Schedule 2 Controlled Drug issued three weeks previously (and not forward dated).

    • B. 

      A prescription for 28 days supply of a Schedule 3 Controlled Drug issued six weeks previously (and not forward dated).

    • C. 

      A prescription for 28 days supply of a Schedule 2 Controlled Drug issued three weeks previously (and not forward dated), with the total quantity written only in figures.

    • D. 

      A repeat supply, made six weeks after the original dispensing, of a Schedule 4 Controlled Drug for which repeats are allowed, on a private prescription requesting one repeat but with no specification, either of the date or length of time after the initial supply, as to when the repeat is to be made.

    • E. 

      A repeat supply, made one year after the original dispensing, of a Schedule 5 Controlled Drug on a private prescription requesting one repeat, but with no specification, either of the date or length of time after the initial supply, as to when the repeat is to be made.

  • 13. 
    In order to make 200ml of Gentian Mixture Alkaline BP, which contains 50 per cent double strength chloroform water, you would need to use:   1. 0.25ml of chloroform 2. 2.5ml of concentrated chloroform water, which contains 10 per cent chloroform 3. 10ml of chloroform spirit, which contains chloroform 1 part in 20   One or more of the responses below is (are) correct. Decide which of the responses is (are) correct. Then choose:   A if 1, 2 and 3 are correct B if 1 and 2 only are correct C if 2 and 3 only are correct D if 1 only is correct E if 3 only is correct   Directions Summarised A 1,2,3 B 1,2 C 2,3 D 1 only E 3 only  
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 14. 
    Directions:  For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:   For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:   A if 1,2 and 3 are correct B if 1 and 2 only are correct C if 2 and 3 only are correct D if 1 only is correct E if 3 only is correct   Directions Summarised A 1,2,3 B 1,2 C 2,3 D 1 only E 3 only   Which of the following symptoms might indicate that a patient who is taking levothyroxine is on too high a dose? 1. Diarrhoea 2. Sweating 3. Weight gain
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 15. 
    A pregnant woman taking medication for which one of the following conditions is at increased risk of giving birth to a baby with spina bifida?
    • A. 

      Asthma

    • B. 

      Chrohn's disease

    • C. 

      Epilepsy

    • D. 

      Diabetes

    • E. 

      Hypertension

  • 16. 
    Directions:  For the question below, ONE or MORE of the responses is (are) correct. Decide which of the responses is (are) correct. Then choose:   A if 1,2 and 3 are correct B if 1 and 2 only are correct C if 2 and 3 only are correct D if 1 only is correct E if 3 only is correct   Directions Summarised A 1,2,3 B 1,2 C 2,3 D 1 only E 3 only   For which of the following could you lawfully make an emergency supply of a prescription only medicine at the request of a patient?   1.      A person who has previously been prescribed the medicine by a doctor in France   2.      A person who has previously been prescribed the medicine by a dentist in Germany   3.      A person who has previously been prescribed the medicine by a dentist in the United Kingdom
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 17. 
    Your pharmacy participates in a ‘Heart Health’ scheme run by your local PCT, in which you measure patients’ height, weight, blood pressure and, depending on results, offer lifestyle advice or refer them to their GP. A 40 year old male patient weighs 70 kg and is 1.8 metres in height. His blood pressure is 160/110mmHg. Assertion/Reason Directions. The following question consists of a statement in the left hand column followed by a second statement in the right hand column. Decide whether the first statement is true or false. Decide whether the second statement is true or false. Then choose: A.         If both statements are true and the second statement is a correct      explanation of the first statement. B.        If both statements are true but the second statement is not a correct            explanation of the first statement. C.        If the first statement is true but the second statement is false. D.        If the first statement is false but the second statement is true. E.         If both statements are false.  First statement Second statement He should be referred to his GP.   He is overweight.   Directions Summarised   First statement Second statement   A True True 2nd statement is a correct explanation of the first B True True 2nd statement is not a correct explanation of the first C True False   D False True   E False False    
    • A. 

      A

    • B. 

      B

    • C. 

      C

    • D. 

      D

    • E. 

      E

  • 18. 
    Which one of the of the following side-effects of antipsychotic drugs relates exclusively to males?
    • A. 

      Akathisia

    • B. 

      Dystonia

    • C. 

      Galactorrhoea

    • D. 

      Gynaecomastia

    • E. 

      Tardive Dyskinesia

  • 19. 
    A patient with non-insulin dependent diabetes has been admitted to the ward for which you are the clinical pharmacist, to investigate the cause of his poor blood glucose control. He takes gliclazide tablets to control his blood glucose levels. Which one of the other medicines he takes, listed below, is the most likely to have adversely affected his blood glucose levels?
    • A. 

      Aspirin 75mg OM

    • B. 

      Bendroflumethiazide 2.5mg OM

    • C. 

      Prazosin 1mg TDS

    • D. 

      Simvastatin 40mg ON

    • E. 

      Tramadol 100mg QDS

  • 20. 
    The following is an extract from a prescription:   Norethisterone 5 mg tablets, one tds from day 5 to 24 of menstrual cycle, supply 4 cycles.    How many tablets should you supply?
    • A. 

      168

    • B. 

      252

    • C. 

      320

    • D. 

      228

    • E. 

      240

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