Pharmacotherapy Of Hypertension (Htn)

42 Questions | Total Attempts: 363

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Pharmacotherapy Of Hypertension (Htn)

Hypertension is a very serious case if not managed as it caused a lot of death daily. This condition is a result of blood having high force against the artery and can cause even heart attacks. As a pharmacist, you need to know how to perform pharmacotherapy on a patient with high blood pressure. The quiz below will test out just how much you understood.


Questions and Answers
  • 1. 
    From 1999 to 2000 HTN was slightly more prevalent in men (30.1%) than women (27.1%). However, the prevalence is increasing in women and remaining unchanged in men. Men have a higher prevalence of HTN than women until age ___.  
    • A. 

      35

    • B. 

      45

    • C. 

      55

    • D. 

      65

  • 2. 
    HTN prevalence is highest in ____________ (43% males, 44% females) when compared to non-Hispanic whites (29%).
    • A. 

      Hispanics

    • B. 

      African-Americans

    • C. 

      Asians

    • D. 

      Native Americans

    • E. 

      McDonaldicans

  • 3. 
    What is the major cause of essential HTN?
    • A. 

      Chronic kidney disease

    • B. 

      Genetics

    • C. 

      Sympathetic overactivity

    • D. 

      Increased renin

    • E. 

      Unknown

  • 4. 
    What are some causes of secondary hypertension? Select all that apply.
    • A. 

      Cushing's syndrome

    • B. 

      Chronic kidney disease

    • C. 

      Pheochromocytoma

    • D. 

      Drug-induced

    • E. 

      COPD

  • 5. 
    What are some drugs that cause secondary hypertension? Select all that apply.
    • A. 

      NSAIDS

    • B. 

      Erythropoietin

    • C. 

      Gemfibrozil

    • D. 

      Oral contraceptives

    • E. 

      Ambien

  • 6. 
    What is the difference from hypertensive urgency to an emergency? Select all that apply.
    • A. 

      Urgency does not cause organ damage

    • B. 

      An example of urgency is unstable angina, while an emergency is an acute MI.

    • C. 

      You can treat an emergency is nifedipine IR.

    • D. 

      Perioperative HTN and optic disk edema are examples of urgency.

    • E. 

      You can treat urgency with nifedipine IR.

  • 7. 
    Hemodynamically, blood pressure is a product of ____________. Select the two that best apply.
    • A. 

      Blood flow

    • B. 

      Stroke volume

    • C. 

      Peripheral resistance

    • D. 

      Atrial natriuretic peptide

    • E. 

      Cardiac output

  • 8. 
    A patient presents with a BP of 140/85. This patient is classified as having:
    • A. 

      Pre-hypertension

    • B. 

      Normal

    • C. 

      Stage I HTN

    • D. 

      Stage II HTN

  • 9. 
    Can you diagnose HTN based on a single elevated blood pressure reading?
    • A. 

      Yes

    • B. 

      No

  • 10. 
    The proposed mechanisms behind high sodium intake and blood pressure include an increase in intracellular calcium, insulin resistance, a paradoxical rise in atrial natriuretic peptide, and other pressor effects.
    • A. 

      True

    • B. 

      False

  • 11. 
    Hypertension is a significant cause of heart failure, but not of endstage renal disease.
    • A. 

      True

    • B. 

      False

  • 12. 
    Patient failing to achieve goal blood pressure despite maximum doses of two antihypertensive agents should be carefully screened for resistant hypertension.
    • A. 

      True

    • B. 

      False

  • 13. 
    Hypertensive patients are usually symptomatic.
    • A. 

      True

    • B. 

      False

  • 14. 
    A stethoscope placed over the brachial artery in the antecubital fossa identifies the first and last audible ________, which should be taken as systolic and diastolic pressure, respectively.
    • A. 

      S3

    • B. 

      Korotkoff sounds

    • C. 

      Split S2

    • D. 

      Wernicke sounds

  • 15. 
    The DASH trial demonstrated that a diet high in fruits, vegetables, and low-fat dairy products, along with a reduced intake of total and saturated fat, significantly reduced blood pressure in as little 8 weeks.
    • A. 

      True

    • B. 

      False

  • 16. 
    Which drug is twice as potent as hydrochlorothiazide?
    • A. 

      Indapamide

    • B. 

      Chlorthalidone

    • C. 

      Furosemide

    • D. 

      Bumetanide

    • E. 

      Doxazosin

  • 17. 
    Which aldosterone antagonist is contraindicated in patients with estimated creatinine clearance less than 50mL/minute or serum creatinine greater than 1.8mg/dL in women or greater than 2mg/dL in men?
    • A. 

      Spironolactone

    • B. 

      Eplerenone

    • C. 

      Doxazosin

    • D. 

      Verapamil

    • E. 

      Quinapril

  • 18. 
    A patient presents with a blood pressure of 55 bpm. Which drug(s) should you use cautiously with this patient?
    • A. 

      Hydrochlorothiazide

    • B. 

      Metoprolol

    • C. 

      Amlodipine

    • D. 

      Metoprolol and Amlodipine

    • E. 

      Metoprolol and Verapamil/Diltiazem

  • 19. 
    Which drugs can increase potassium? Select all that apply.
    • A. 

      Hydrochlorothiazide

    • B. 

      Spironolactone

    • C. 

      Benazepril

    • D. 

      Valsartan

    • E. 

      Propranolol

  • 20. 
    Which drug can cause hyperkalemia and gynecomastia?
    • A. 

      Chlorthalidone

    • B. 

      Carteolol

    • C. 

      Terazosin

    • D. 

      Spironolactone

  • 21. 
    Which drugs have a compelling indication for diabetes (in addition to CCBS and chlorthalidone)?
    • A. 

      ACEs and ARBs

    • B. 

      Loop Diuretics

    • C. 

      Aldosterone Antagonists

    • D. 

      Alpha blockers

  • 22. 
    Abrupt discontinuation of these drugs causes rebound HTN.
    • A. 

      Indapamide and Atenolol

    • B. 

      Fosinopril and Atenolol

    • C. 

      Irbesartan and Clonidine

    • D. 

      Atenolol and Indapamide

    • E. 

      Atenolol and Clonidine

  • 23. 
    Which drugs do not work well alone in the treatment of HTN and should be used cautiously in patients with renal insufficiency.
    • A. 

      ACE inhibitors

    • B. 

      Potassium Sparing Diuretics

    • C. 

      Loop Diuretics

  • 24. 
    51% of patients with CV disease die of:
    • A. 

      Stroke

    • B. 

      HBP

    • C. 

      Coronary Heart Disease

    • D. 

      HF

  • 25. 
    CVD risk factors include: (select all that apply.)
    • A. 

      Dyslipidemia

    • B. 

      Cigarette smoking

    • C. 

      Microalbuminuria or estimated GFR <60 mL/min

    • D. 

      DM

    • E. 

      Age (older than 35 for men, 45 for women)

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