Pharmacotherapy Of Hypertension (Htn)
Hypertension is a very serious case if not managed as it caused a lot of death daily. This condition is a result of blood having high force against the artery and can cause even heart attacks. As a pharmacist, you need to know how to perform pharmacotherapy on a patient with high blood pressure. The quiz below will test out just how much you understood.
- 1.From 1999 to 2000 HTN was slightly more prevalent in men (30.1%) than women (27.1%). However, the prevalence is increasing in women and remaining unchanged in men. Men have a higher prevalence of HTN than women until age ___.
- A.
35
- B.
45
- C.
55
- D.
65
- 2.HTN prevalence is highest in ____________ (43% males, 44% females) when compared to non-Hispanic whites (29%).
- A.
Hispanics
- B.
African-Americans
- C.
Asians
- D.
Native Americans
- E.
McDonaldicans
- 3.What is the major cause of essential HTN?
- A.
Chronic kidney disease
- B.
Genetics
- C.
Sympathetic overactivity
- D.
Increased renin
- E.
Unknown
- 4.What are some causes of secondary hypertension? Select all that apply.
- A.
Cushing's syndrome
- B.
Chronic kidney disease
- C.
Pheochromocytoma
- D.
Drug-induced
- E.
COPD
- 5.What are some drugs that cause secondary hypertension? Select all that apply.
- A.
NSAIDS
- B.
Erythropoietin
- C.
Gemfibrozil
- D.
Oral contraceptives
- E.
Ambien
- 6.What is the difference from hypertensive urgency to an emergency? Select all that apply.
- A.
Urgency does not cause organ damage
- B.
An example of urgency is unstable angina, while an emergency is an acute MI.
- C.
You can treat an emergency is nifedipine IR.
- D.
Perioperative HTN and optic disk edema are examples of urgency.
- E.
You can treat urgency with nifedipine IR.
- 7.Hemodynamically, blood pressure is a product of ____________. Select the two that best apply.
- A.
Blood flow
- B.
Stroke volume
- C.
Peripheral resistance
- D.
Atrial natriuretic peptide
- E.
Cardiac output
- 8.A patient presents with a BP of 140/85. This patient is classified as having:
- A.
Pre-hypertension
- B.
Normal
- C.
Stage I HTN
- D.
Stage II HTN
- 9.Can you diagnose HTN based on a single elevated blood pressure reading?
- A.
Yes
- B.
No
- 10.The proposed mechanisms behind high sodium intake and blood pressure include an increase in intracellular calcium, insulin resistance, a paradoxical rise in atrial natriuretic peptide, and other pressor effects.
- A.
True
- B.
False
- 11.Hypertension is a significant cause of heart failure, but not of endstage renal disease.
- A.
True
- B.
False
- 12.Patient failing to achieve goal blood pressure despite maximum doses of two antihypertensive agents should be carefully screened for resistant hypertension.
- A.
True
- B.
False
- 13.Hypertensive patients are usually symptomatic.
- A.
True
- B.
False
- 14.A stethoscope placed over the brachial artery in the antecubital fossa identifies the first and last audible ________, which should be taken as systolic and diastolic pressure, respectively.
- A.
S3
- B.
Korotkoff sounds
- C.
Split S2
- D.
Wernicke sounds
- 15.The DASH trial demonstrated that a diet high in fruits, vegetables, and low-fat dairy products, along with a reduced intake of total and saturated fat, significantly reduced blood pressure in as little 8 weeks.
- A.
True
- B.
False
- 16.Which drug is twice as potent as hydrochlorothiazide?
- A.
Indapamide
- B.
Chlorthalidone
- C.
Furosemide
- D.
Bumetanide
- E.
Doxazosin
- 17.Which aldosterone antagonist is contraindicated in patients with estimated creatinine clearance less than 50mL/minute or serum creatinine greater than 1.8mg/dL in women or greater than 2mg/dL in men?
- A.
Spironolactone
- B.
Eplerenone
- C.
Doxazosin
- D.
Verapamil
- E.
Quinapril
- 18.A patient presents with a blood pressure of 55 bpm. Which drug(s) should you use cautiously with this patient?
- A.
Hydrochlorothiazide
- B.
Metoprolol
- C.
Amlodipine
- D.
Metoprolol and Amlodipine
- E.
Metoprolol and Verapamil/Diltiazem
- 19.Which drugs can increase potassium? Select all that apply.
- A.
Hydrochlorothiazide
- B.
Spironolactone
- C.
Benazepril
- D.
Valsartan
- E.
Propranolol
- 20.Which drug can cause hyperkalemia and gynecomastia?
- A.
Chlorthalidone
- B.
Carteolol
- C.
Terazosin
- D.
Spironolactone
- 21.Which drugs have a compelling indication for diabetes (in addition to CCBS and chlorthalidone)?
- A.
ACEs and ARBs
- B.
Loop Diuretics
- C.
Aldosterone Antagonists
- D.
Alpha blockers
- 22.Abrupt discontinuation of these drugs causes rebound HTN.
- A.
Indapamide and Atenolol
- B.
Fosinopril and Atenolol
- C.
Irbesartan and Clonidine
- D.
Atenolol and Indapamide
- E.
Atenolol and Clonidine
- 23.Which drugs do not work well alone in the treatment of HTN and should be used cautiously in patients with renal insufficiency.
- A.
ACE inhibitors
- B.
Potassium Sparing Diuretics
- C.
Loop Diuretics
- 24.51% of patients with CV disease die of:
- A.
Stroke
- B.
HBP
- C.
Coronary Heart Disease
- D.
HF
- 25.CVD risk factors include: (select all that apply.)
- A.
Dyslipidemia
- B.
Cigarette smoking
- C.
Microalbuminuria or estimated GFR <60 mL/min
- D.
DM
- E.
Age (older than 35 for men, 45 for women)
Questions: 7 | Attempts: 24779 | Last updated: May 26, 2021
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Sample QuestionKids,Between the ages of 1 and 10 are the only ones proneto hypertension
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Sample QuestionMr. Patterson is on Hydrocholorthiazide for his hypertension. You know Mr. Patterson understands the medication when he says:
Questions: 12 | Attempts: 1361 | Last updated: Sep 18, 2014
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Sample QuestionTA is a 58 year old male. He reports to the emergency room after being seen at the his primary care physician's clinic. His blood pressure upon entering the emergency room is 200/130 mm Hg and he has shortness of breath (SOB) with a headache. He has a past medical history of hypertension x 5 years. He denies smoking and illicit drug use. He rarely drinks alcohol. His medications are the following: Lisinopril 20 mg QD, HCTZ 25 mg QD. His labs are all within normal limits. How would you characterize his hypertension and what is the goal blood pressure?
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