Pharmacotherapy- Dyslipidemia

1. Gemfibrozil increases the incidence of myopathy with statins the most.

True

False

2. The primary action of fibrates is to lower TG

True

False

secondary to increase HDL

Explanation

secondary to increase HDL

3. Niacin should be watched in Pts. with Gout and DM

True

False

4. The SR formulations of Niacin can cause hepatotoxicity

True

False

5. Bile Acid Resins: bind bile acid in the gut resulting in increased bile acid formation from cholesterol

True

False

6. Therapeutic Lifestyle Changes include

Reducing total cholesterol/day to

Saturated fat

Increase fiber and plant sterols as options to decrease LDL

Weigh Management

Increase physical exercise

Submit

7. In high risk patients LDL goal is <100mg/dl and very high risk patients goal is <70 mg.dl

True

False

8. The average LDL in the country is 130mg/dl

True

False

9. The optimal level of LDL-C is and the Very High level of LDL-C is_

140

159

190

220

10. Which levels of TG are correct?

Desirable

Borderline High 150-199

High >200-499

Very High > 500

Submit

11. Pts. with TG >500 are at an increased risk of ______

Heart attack

Failing this test

Pancreatitis

Irritable bowel syndrome

Breast cancer

12. What can be a criteria for metabolic syndrome?

Waist: Male >40inFemale >35

TG >150

HDL: Male

BP: > 130/85

Fasting Blood Glucose >100

Submit

13. Which of these statements are correct?

Optimal LDL is

Near/above optimal LDL is 100-129

Borderline high LDL is 130-159

High LDL is 160-189

Very High LDL is >190

Submit

14. What is the Framingham Point Scores missing that is important in guessing your 10 year risk of CHD

Age

HDL

Family History

Smoking Status

Systolic BP

15. What is not an adverse effect of Bile acid resins:

Constipation

LFT's increased

Flatulence

Nausea

Poor taste

16. Omega-3 can increase LDL concentrations

True

False

17. For mod-high risk patients, LDL goal is <100mg/dl and <70 is optional

True

False

Explanation

18. When TG get > 400, they become the primary goal before LDL lowering

True

False

TG >500

Explanation

TG >500

19. Patients with metabolic syndrome are ____ times as likely to develop type 2 diabetes

2

3

4

5

6

20. Natural Products for Lipids: Wine

Deacrease HDL

Increases HDL

Increases C-reactive Protein

Decreases C-reactive protein

Submit

21. What are the emerging risk factors for CHD

Lipoprotein A

Homocysteine

Prothrombotic/proinflammatory factors

C-reactive protein

Submit

22. The TG lowering effect of omega-3 fatty acids is ________mg EPA/DHA/Day

1000-2000

100-200

10-20

2000-5000

200-500

23. Patients with metabolic syndrome are ____ times as likely to develop CHD.

2

3

4

5

6

24. Which drugs cause an increase of myopathy/rhabdomyolysis with HMG-CoA RI

Cyclosporine

Ketoconazole, fluconazole, itraconazole

Amiodarone

Gemfibrozil

Verapamil, diltiazem

Submit

25. Which HMG-CoA Reductase Inhibitors are most susceptible to drug interactions?

Atorvastatin

Simvastatin

Pitavastatin

Lovastatin

Cerivastatin

Submit

26. Which drugs increase the levels of HDL?

Ezetimibe

Fibrates

Niacin

Resins

Satins

Submit

27. What are the most effective agents in pts with high TG >500

Bile acid Resins

Niacin

Fibrates

Omega-3 fatty acids

Statins

Submit

28. Ways to avoid flushing with Niacin

ASA 325mg

ASA 81mg

Motrin 200mg

These should be used 30 minutes before niacin

These should be used 30 minutes after niacin

Submit

Pharmacotherapy- Dyslipidemia

1. Gemfibrozil increases the incidence of myopathy with statins the most.

2.

What first name or nickname would you like us to use?

2. The primary action of fibrates is to lower TG

3. Niacin should be watched in Pts. with Gout and DM

4. The SR formulations of Niacin can cause hepatotoxicity

5. Bile Acid Resins: bind bile acid in the gut resulting in increased bile acid formation from cholesterol

6. Therapeutic Lifestyle Changes include

7. In high risk patients LDL goal is <100mg/dl and very high risk patients goal is <70 mg.dl

8. The average LDL in the country is 130mg/dl

9. The optimal level of LDL-C is ______ and the Very High level of LDL-C is_______

10. Which levels of TG are correct?

11. Pts. with TG >500 are at an increased risk of ______

12. What can be a criteria for metabolic syndrome?

13. Which of these statements are correct?

14. What is the Framingham Point Scores missing that is important in guessing your 10 year risk of CHD

15. What is not an adverse effect of Bile acid resins:

16. Omega-3 can increase LDL concentrations

17. For mod-high risk patients, LDL goal is <100mg/dl and <70 is optional

18. When TG get > 400, they become the primary goal before LDL lowering

19. Patients with metabolic syndrome are ____ times as likely to develop type 2 diabetes

20. Natural Products for Lipids: Wine

21. What are the emerging risk factors for CHD

22. The TG lowering effect of omega-3 fatty acids is ________mg EPA/DHA/Day

23. Patients with metabolic syndrome are ____ times as likely to develop CHD.

24. Which drugs cause an increase of myopathy/rhabdomyolysis with HMG-CoA RI

25. Which HMG-CoA Reductase Inhibitors are most susceptible to drug interactions?

26. Which drugs increase the levels of HDL?

27. What are the most effective agents in pts with high TG >500

28. Ways to avoid flushing with Niacin

9. The optimal level of LDL-C is and the Very High level of LDL-C is_