Pharm Tech Chapter 10 (Basic Biopharmaceutics)

57 Questions | By Ashleycream | Updated: Mar 21, 2022 | Attempts: 5431

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Pharm Tech Chapter 10 (Basic Biopharmaceutics) - Quiz

How drugs work, concentration & effect, ADME Processes & diffusion, absorption, distribution, metabolism, excretion, bioequivalence

Questions and Answers

1.

The subtstantial degradtion of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches the systemic circulation.
- A.
  
  First-pass metabolism
- B.
  
  Dispostion
- C.
  
  Antagonist
- D.
  
  Hydrophilic
2.

The increase in hepatic enzyme activity that results in greater metabolism of drugs
- A.
  
  Bioavailability
- B.
  
  Elimination
- C.
  
  Enzyme
- D.
  
  Enzyme induction
3.

The study of the factors associated with drug products and physiological processes, and the resulting systemic concentration of drugs.
- A.
  
  Disposition
- B.
  
  Complexation
- C.
  
  Biopharmaceutics
- D.
  
  Bioavailability
4.

The comparison of bioavailability between two dosage forms.
- A.
  
  Bioequivalency
- B.
  
  Bioavailablity
- C.
  
  Biopharmaceutics
- D.
  
  Biological
5.

The relative amount of an administered dose that reaches the general circulation and the rate at which this occurs
- A.
  
  Biological
- B.
  
  Bioavailability
- C.
  
  Biopharmaceutics
- D.
  
  Bioequivalency
6.

Water repelling; cannot associate with water
- A.
  
  Hydrophilic
- B.
  
  Hydrophobic
- C.
  
  Hydraulic
- D.
  
  Hydrogen
7.

Capable of associating with or absorbing water
- A.
  
  Hydrophilic
- B.
  
  Hydrophobic
- C.
  
  Hydrologic
- D.
  
  Hydraulic
8.

The blood filitering process of the nephron
- A.
  
  Glomerular filtration
- B.
  
  Disposition
- C.
  
  Complexation
- D.
  
  Enzyme
9.

The time a drug will stay in the stomach before it is emptied into the small intestine
- A.
  
  Glomerular filtration
- B.
  
  Gastric emptying time
- C.
  
  Disposition
- D.
  
  Agonist
10.

The decrease in hepatic enzyme activity that resutls in reduced metabolism of drugs
- A.
  
  First-pass metabolism
- B.
  
  Hydrophilic
- C.
  
  Gastric emptying time
- D.
  
  Enzyme inhibition
11.

A complex protien that catalyzes chemical reactions
- A.
  
  Enzyme
- B.
  
  Enzyme induction
- C.
  
  Enzyme inhibition
- D.
  
  Enzymes from fruit
12.

The transfer of drugs and their metabolites from the liver to the bile in the gall bladder, then into the intestine, and then back into circulation
- A.
  
  Enzyme
- B.
  
  Enterohepatic cycling
- C.
  
  First-past metabolism
- D.
  
  Glomerular filtration
13.

The porcess of metabolism and excretion
- A.
  
  Elimination
- B.
  
  Disposition
- C.
  
  Antagonists
- D.
  
  Absorption
14.

The time the drug concentration is above the MEC.
- A.
  
  Elimination
- B.
  
  Dosposition
- C.
  
  Duration of action
- D.
  
  Absorption
15.

A term sometimes used to refer to all the ADME processes together.
- A.
  
  Complexation
- B.
  
  Disposition
- C.
  
  Enzyme inhibition
- D.
  
  Enzyme
16.

When different molecules associate or attach to each other
- A.
  
  Biopharmaceutics
- B.
  
  Elimination
- C.
  
  Complexation
- D.
  
  Bio hazzard
17.

The movement of drugs from an area of the lower cconcentration to an area of higher concentration; requires cellular energy
- A.
  
  Active transport
- B.
  
  Absorption
- C.
  
  Antagonist
- D.
  
  Agonist
18.

The movement of drug from the dosage formulation to the blood
- A.
  
  Absorption
- B.
  
  Active transport
- C.
  
  Hydrate
- D.
  
  First-pass metabolism
19.

Drugs that activiate receptors to accelerate or slow normal cellular fuction
- A.
  
  Antagonist
- B.
  
  Agonists
- C.
  
  Disposition
- D.
  
  Lipoidal
20.

Drugs that bind with receptors but do not activate them
- A.
  
  Agonists
- B.
  
  Antagonist
- C.
  
  Antiviral
- D.
  
  Antibacteria
21.

Fat like sustance
- A.
  
  Grease
- B.
  
  Chicken
- C.
  
  Emulsion
- D.
  
  Lipoidal
22.

The attachment of a drug molecule to a protien, effectively making the drug inactive
- A.
  
  Metabolite
- B.
  
  Metabolife
- C.
  
  Protien binding
- D.
  
  None of the above
23.

The cellular materila which interacts with the drug
- A.
  
  Selective (action)
- B.
  
  Receptor
- C.
  
  Selective (action)
- D.
  
  Onset of action
24.

The movment of drugs from and area of higher concentration to lower concentration
- A.
  
  Pharmaceutical alternative
- B.
  
  Passive diffusion
- C.
  
  Receptor
- D.
  
  Site of action
25.

The characteristic of a drug that makes it action specific to certain receptors
- A.
  
  Selective (action)
- B.
  
  Passive diffusion
- C.
  
  Nephron
- D.
  
  Nephrons